487 research outputs found
Axon-restrictive chondroitin sulfates at the Schwann cell-astroycte interface
No full textpublished_or_final_versionBiochemistryMasterMaster of Philosoph
Sudden onset of breathlessness secondary to diaphragmatic hernia: a case report
No full textWe report a case of sudden onset of breathlessness secondary to diaphragmatic hernia in a 98-year-old woman admitted for recurrent falls.Full Tex
Targeting unopposed neutrophil elastase in chronic respiratory inflammation with heparin oligosaccharides
No full textpublished_or_final_versionBiochemistryMasterMaster of Philosoph
Aged care services in Australia and commentary on lessons learnt
No full textThe Australian aged care service is a mature and evolving service. It is comprehensive with good continuity of care between hospital and community. Innovative models of care that are built on the principles of improved efficiency, better quality, and safety are constantly being introduced as our population is aging, resulting in higher demand in our healthcare services and increasing healthcare cost. Collaborative effort of a multidisciplinary team underpins our successful aged care model as most of our older patients have multiple comorbidities with various functional and psychosocial needs. General practitioners play an important role in the care of older patients in the community.Full Tex
The role of heparanase in synaptic plasticity at the hippocampus
No full textpublished_or_final_versionBiochemistryMasterMaster of Philosoph
Expression of chondroitin sulfotransferases in relation to cranial motor neuron movements in the embryonic hindbrain
No full textpublished_or_final_versionBiochemistryDoctoralDoctor of Philosoph
Commentary on the opportunities of research in Geriatrics and Gerontology
No full textThis first edition of “Aging Medicine” marks the birth of a new journal in the field of Geriatrics and Gerontology. It serves as a timely reminder to focus on research opportunities in this field, shedding light on where research effort is best directed.
Clinicians often need to make adjustments when applying investigative or study results to older patients because many investigative results of older patients vary from the general population and many therapeutic studies exclude older patients for a variety of reasons. For instance, it is well known that antinuclear antibody (ANA) is a sensitive test for rheumatological conditions such as systemic lupus erythematosus. Therefore, many clinicians and laboratories would proceed with testing extractable nuclear antigen (ENA) when ANA is positive. However, in many older persons, ANA is modestly increased and may not necessarily reflect a disease process and so automatic request for ENA is unjustified. Furthermore, many older patients have multiple medical comorbidities and such patients are usually excluded from therapeutic trials. Therefore, when considering treatments, clinicians would often have to weigh up the benefits—especially if the benefit is only found in the longer term—against the side effects that treatments may bring in the shorter term. This is because many older patients’ life expectancy is limited by their medical comorbidities and may not survive to enjoy the long‐term benefits if treated. Such complex considerations may not be required in the younger population without medical comorbidities. Hence, the guidelines of treatments found in the literature are not always generalizable to our older population.Full Tex
Role of chondroitin sulfates in the projection of vestibular commissures during embryonic hindbrain development
No full textpublished_or_final_versionPhysiologyMasterMaster of Philosoph
In vitro and in vivo studies of skin-derived Schwann cells in nerve regeneration
No full textpublished_or_final_versionPhysiologyDoctoralDoctor of Philosoph
In vitro derivation of myelinatiog Schwann cells for use in chitosan-based nerve guidance channels
No full textpublished_or_final_versionBiochemistryMasterMaster of Philosoph
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