101,674 research outputs found

    Interview with Chad Long

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    Chad Long talks about Honey Bucketshttps://digital.kenyon.edu/ps_interviews/1044/thumbnail.jp

    Mission Incomplete: Why civilians remain at risk in eastern Chad

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    The international community took an important step in deploying the UN and EUFOR mission to volatile and insecure eastern Chad. However, one year on, this mission is not capable of adequately protecting civilians and requires urgent reform. EUFOR has made many civilians feel safer, but as a military force is ill suited to an environment of lawlessness and banditry. A year on, the policing elements of the mission are yet to be deployed. Finally, without a comprehensive political solution to the internal crisis in Chad, there will be no hope of long-term security for the civilians who are currently at risk

    An enzymatic mechanism for calcium current inactivation in dialysed Helix neurones

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    'Wash-out' and inactivation of the Ca current were examined in dialysed, voltage-clamped neurones of Helix aspersa under conditions that isolate the Ca current virtually free of other currents. EGTA or other internal Ca2+ chelators were routinely omitted from the dialysate. The time-dependent loss, or wash-out, of Ca current was slowed by addition to the dialysing solution of agents, such as dibutyryl adenosine 3'-5'-cyclic monophosphate (dibutyryl cyclic AMP), Mg adenosine 5'-triphosphate (ATP) and the catalytic subunit of cyclic-AMP-dependent protein kinase, that promote protein phosphorylation and by EGTA. However, neither the phosphorylation-promoting agents nor internal EGTA prevented wash-out entirely, nor did they significantly restore previously 'washed-out' current. With phosphorylating agents in the dialysing solution, the irreversible development of wash-out was greatly reduced by introduction of leupeptin, an inhibitor of protease activity. Thus, the irreversible component of wash-out appears to result from a Ca-dependent proteolytic process. In the presence of leupeptin alone, Ca current amplitude continued to decline: however, the current could be largely or fully restored with addition of catalytic subunit, dibutyryl cyclic AMP, and Mg ATP to the dialysing solution. Thus, inhibition of proteolysis revealed a reversible component of wash-out that appears to result from dephosphorylation. During perfusion with leupeptin, Mg ATP, dibutyryl cyclic AMP and catalytic subunit the Ca current remained stable for up to several hours without addition of internal Ca2+ buffer. The rate of inactivation of the current that occurs during a depolarizing step showed only a very gradual decline during this time. Under these conditions, perfusion with calcineurin, a Ca-calmodulin-dependent phosphatase, caused a significant increase in the rate of Ca current inactivation. This inactivation was virtually eliminated by introduction of EGTA or by replacement of external Ca2+ with Ba2+, which is consistent with the ion dependency for calmodulin-dependent activation of calcineurin. When ATP in the dialysate was replaced with ATP-gamma-S (adenosine 5'-O-(thiotriphosphate], an analogue that donates a thiophosphate group resistant to hydrolysis, the rate of inactivation slowed. Since Ca-dependent inactivation during step depolarizations is enhanced by conditions that promote dephosphorylation, and Ca current wash-out is slowed by conditions that promote phosphorylation, inactivation and reversible wash-out appear to be related

    Long-Term Contracts in Major League Baseball

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    Long-term deals are one tool that both players and franchises use to manage risk. That tool has been much discussed and empirically tested with respect to player shirking, and has more briefly, and only theoretically, discussed with respect to reducing variance in future payrolls. Our work looks at how patterns of use of long-term contracts are affected by changes in contracting rules established through collective bargaining and by expected changes in franchise revenue streams. To accomplish this, we have assembled the most complete dataset of MLB player contracts to date. We analyze changes in contract length and dollar value across players of different ability levels, at different points in their careers (contract status), by position, across CBA agreements, and further examine if new stadiums and new television deals impact contract terms. We confirm the earlier finding that player performance is systematically higher during contract years than during the early portion of a long-term contract. We also find that inclusion of contract length information significantly reduces the unexplained variation in player salaries.Major League Baseball (MLB); long-term contracts; player salaries and performance; collective bargaining agreements (CBA)

    Chad : Hepatitis E

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    Contaminated drinking water in Chad is the main source for a Hepatitis E outbreak, leading Chad citizens to develop severe illness including jaundice, liver-failure, miscarriage, and death. There are 0.4 physicians for every 10,000 people living in Chad needing healthcare. Of the citizens in Chad, only 42% have access to uncontaminated drinking water. With such a long incubation period for Hepatitis E, the citizens don’t know they are spreading the illness to the rest of their community. Even with the symptoms, the citizens don’t have the access or the capacity for treatment, making Hepatitis E an epidemic in Chad

    Durable Solutions for Internally Displaced Persons: Challenges in eastern Chad

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    Between 2005 and 2007, a combination of regional conflict and national crisis led to the internal displacement of about 180,000 people in eastern Chad. However, the situation has since changed. By March 2012, when this report was produced, incursions by the Janjaweed militia and conflict between government forces and Chadian rebels had largely ended. The Chadian government is now seeking to put an end to the distinction between displaced persons and host communities. Internally displaced persons currently have the choice between three solutions: local integration, relocation or voluntary return to their home village. The goal of this joint report is to reflect on the decisive actions that could provide durable solutions for displacement, taking into account the rights and needs of affected communities. Even if the causes of the initial displacement have now been contained, creating the right set of circumstances for long-term sustainable development still remains a challenge. The Chadian government has publicly recognized that it is responsible for setting up an appropriate framework for durable solutions, ensuring security, rule of law, respect for human rights and access to basic services; however, very little has yet been done by the government to make this a reality

    Report to UNHCR Chad on proposals for livestock and animal owners in Eastern Chad.

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    Estimates of current livestock numbers owned by refugees in the 12 UNCHR camps in eastern Chad vary widely between 173,000 and 427,000 head, using data gathered by camp authorities. Finding adequate food for these animals is becoming an increasing challenge for their owners and is leading to increased tension between refugees and the host communities as they compete for already limited resources. The confinement of livestock within a relatively short distance from the camps is resulting in long-term environmental degradation resulting from over-exploitation of natural resources. Livestock mortality is very high due to high disease incidence exacerbated by poor nutrition. The application of traditional pastoralist management systems to an intensified livestock population is increasing the attrition of livestock, accelerating environmental degradation, increasing the risk of inter-ethnic conflict and, consequentially, failing to ensure that the most benefits possible in terms of added-value are being derived from the available livestock. Solutions to the problem of feeding the livestock belonging to refugees are made complex by the lack of incentive to invest in a region where camp dwellers have no land tenure rights and a strong desire to return home as soon as possible. In order to reduce conflict between refugees and the host community, solutions need to benefit both sectors.Due to the size of a camp and the concentration of dwellings in a small area, comparisons can be made with livestock keeping in a peri-urban environment. The over-grazing by the large numbers of livestock around the camps will result in degradation of the local environment and ultimately livestock may only be able to be kept by following a programme by refugee livestock owners of cutting and carrying available forage back to the immediate vicinity of the camps. An alternative, is that (as we shall later propose) fodder and crop residues are bought and brought in from outside the camp. However far more benefit would certainly derive from a planned programme of growing forage crops, either by the refugees, or endemic villagers who could then sell them to the refugees and gain a valuable additional income. However a balance has to be struck between what is currently an unsustainable situation, characterised by a excessive livestock population carrying out possibly long-term environmental degradation, versus support for an artificial system of livestock management, which will entail interventionary support and management, the planned and budgeted provision of supplementary feed and the perpetuation of a system which disconnects the refugees from their animal ownership and management traditions and knowledge. A series of recommendations will be made that are designed to reduce the overwhelming demand for forage in the short and medium term. If implemented, they should result in smaller, fitter herds of livestock that in the long term can be both more readily repatriated and readapted to the more favourable grazing conditions found in Western Sudan

    Islam and Other Religions in Chad

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    Chad is a country located on the border of the three great religions of the world - Islam, Christianity and traditional religions, also known as the animism. All of them have played some significant role in the history of that country, firstly involved in the beginnings of the empires of Sahel, notorious process of slave raids, subsequently associated with colonization and growing European interests in Africa, the 20th century's civil war and finally connected to the vanguard of the „war on terror". The article presents the history of the three religions in Chad and their influence on politics and society. For several hundred years Islamic domination over the followers of the other religions has caused frictions and contention. The religious differences have indirectly been responsible for the 25-year long conflict, followed by thousands of casualties. In the final part of the article the author depicts the contemporary state of inter-religious affairs and attitude of the government towards the religious issues. Due to some joint attempts of the government of Chad and international society, the religious differences and flashpoints are believed not to pose such a threat to peace and stability as it had been before. Despite of its unfortunate location in the „clash of civilization" region, Chad may set a good example that the peaceful co-existence of Islam and Christianity is possible

    Frankfurt book fair: cancelled prize ceremony for Palestinian author is part of a long history of political zigzagging

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    First paragraph: The Frankfurt Buchmesse, or book fair, is the world’s largest publishing industry gathering, attracting thousands of exhibitors every October. On one level, it’s a business event focused on creating buzz for forthcoming bestsellers, trading rights and discussing industry developments. On another, it’s a public celebration of books and the values associated with them.https://theconversation.com/frankfurt-book-fair-cancelled-prize-ceremony-for-palestinian-author-is-part-of-a-long-history-of-political-zigzagging-21574
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