67 research outputs found
Author Correction: A new ape from Türkiye and the radiation of late Miocene hominines
No full textCorrection to: Communications Biology, published online 23 August 2023. In the original version of the Article, two authors and their affiliations were omitted. In the original version of the Article, author first names were not provided for all authors. The corrected author list and affiliations are provided below. This has now been corrected in the HTML and PDF versions of the article. Ayla Sevim-Erol1, David R. Begun2, Alper Yavuz3, Erhan Tarhan4, Çilem Sönmez Sözer1, Serdar Mayda5, Lars W. van den Hoek Ostende6, Robert M. G. Martin2 ; M. Cihat Alçiçek7 1 Ankara University, Faculty of Languages History and Geography, Department of Anthropology, Ankara, Türkiye 2 Department of Anthropology, University of Toronto, Toronto, ON, Canada 3 Mehmet Akif Ersoy University of Science and Letters, Department of Anthropology, Burdur, Türkiye 4 Hitit University Faculty of Science and Letters, Department of Anthropology, Çorum, Türkiye 5 Ege University Fakulty of Science, Department of Biology, İzmir, Türkiye 6 Naturalis Biodiversity Center, Leiden, The Netherlands 7 Pamukkale University, Department of Geology, 20070 Denizli, Türkiye The Author Contributions section should read “A.S.E. is the PR of the project, secured funding for excavations and lab analysis and directed excavations. A.S.E. and D.R.B. are responsible for data curation, acquired funding and supervised research. D.R.B. conceptualized the analysis, conducted the investigation, developed the methodology, prepared the original draft and all subsequent versions. C.S.S., S.M., L.W.vdH. and C.A. contributed their analysis of geological and paleontological results. R.M.G.M. was responsible for the segmentation and analysis of the scans of the mandible. A.Y and E.T. participated in the excavations.” This has now been corrected in the HTML and PDF versions of the article. © 2023, Springer Nature Limited
Navigation problems of ICSI or naive blastocyst can be solved with artificial blastocyst
No full textAbstract Embryos have evolved a remarkable capacity to find implantation site. The impressive navigation ability of natural blastocysts may rely on highly sensitive signals arising from embryos and specialized signal processing strategies in the endometrium. Navigation capabilities may be compromised in ICSI embryos because of altered biochemical signaling. The design and delivery of artificial blastocyst (AB) carrying strong chemical signals may allow ICSI embryos to more easily locate to and be retained in the implantation zone. ICSI embryos will attach easily to the implantation zone after it is found by the AB. Co-transfer of the AB together with the ICSI embryo may overcome potential difficulties in implantation due to impaired embryo-maternal communication in cases with implantation failure
Laparoscopic endometrioma resection increases peri-implantation endometrial HOXA-10 and HOXA-11 mRNA expression
No full textObjective: To determine whether laparoscopic endometrioma resection alters peri-implantation endometrial HOXA-10, HOXA-11, LIF, ITGB3 and ITGAV mRNA expression. Design: Case-control study. Setting: Medical school. Patient(s): Twenty infertile patients with uni-or bilateral endometrioma, five infertile patients having nonendometriotic benign ovarian cyst, and five fertile control subjects. Intervention(s): Mid-luteal-phase endometrial sampling was performed at the time of surgery. Second endometrial biopsies were obtained 3 months after laparoscopic endometrioma resection during the mid-luteal phase of the cycle. Main Outcome Measure(s): Endometrial HOXA-10, HOXA-11, LIF, ITGAV, and ITGB3 mRNA expressions were evaluated with the use of reverse-transcription polymerase chain reaction. Result(s): Significantly decreased endometrial ITGAV mRNA expression was noted in biopsies obtained from endometrioma and nonendometriotic cyst groups before surgery. Trends toward decreased endometrial HOXA-10, HOXA-11, LIF, and ITGB3 mRNA expressions were noted in the endometrioma and nonendometriotic cyst groups before surgery compared with the fertile subjects. However, the differences failed to show statistical significance. Compared with preoperative values, significantly increased HOXA-10 (12.1-fold change) and HOXA-11 (17.2-fold change) mRNA expressions were noted in endometrial biopsies obtained from subjects who were undergoing endometrioma surgery. Fold change in endometrial ITGAV mRNA after endometrioma surgery was found to be 30.1 and indicated a positive regulation. However, this fold increase was statistically insignificant. Expressions of these endometrial receptivity markers did not change significantly after surgical removal of nonendometriotic benign ovarian cysts. Conclusion(s): Laparoscopic endometrioma resection increases peri-implantation endometrial HOXA-10 and HOXA-11 mRNA expression, suggesting an improvement in endometrial receptivity. (C) 2015 by American Society for Reproductive Medicine.2AUG356-36510
Pain evaluation in a sample of Turkish children with cerebral palsy and its association with dependency level, verbal abilities, and the quality of life of patients and sociodemographic status, depression, and quality of life of their caregivers
No full textObjectives: This study aims to evaluate pain in children with cerebral palsy (CP), to investigate its association with dependency level, verbal abilities, and the quality of life (QoL) of children and sociodemographic status, depression levels, and QoL of their caregivers. Patients and methods: Between February 2016 and April 2016, a total of 85 children (56 males, 29 females; mean age 7.1 +/- 2.5 years; range, 4 to 12 years) with CP were included. Their sociodemographic data, gross motor functional levels, verbal abilities (verbal and non-verbal) were evaluated. The children were categorized as independent (Gross Motor Function Classification System [GMFCS] 1), partially dependent (GMFCS 2,3), and totally dependent (GMFCS 4,5). The Non-Communicating Children's Pain Checklist - Revised (NCCPC-R), the Caregiver Priorities & Child Health Index of Life with Disabilities (CPCHILD), the Nottingham Health Profile (NHP), and the Beck Depression Inventory (BDI) were used for the evaluation. Results: A total of 50 (58.8%) of the children were verbal, while 35 (41.2%) were non-verbal. Of the patients, 47.1% were totally dependent, 37.6% were partially dependent, and 15.3% were independent. Pain was less frequent in the independent group, compared to the partially and totally dependent groups (p=0.04; p=0.013). There were no statistically significant difference in perceived pain according to the CPCHILD and NCCPC-R scores, when low and high socioeconomic status were compared (p>0.05). The QoL scores of children who were totally dependent and non-verbal were statistically significantly lower than those of the other children (p=0.0001, p=0.0001). A statistically significantly negative correlation between increased totally dependent children's QoL scores and decreased QoL scores of the caregivers was observed (r=-0.429 p=0.006). The children with pain had a decreased QoL (p=0.03). The QoL of caregivers decreased and the depression scores of caregivers increased, as the pain scores of the children increased (r=0.291, p=0.007; r=-0.455, p=0.0001). Conclusion: Our study results show that pain is more frequent in children with CP who are dependent and non-verbal, and it negatively affects the QoL of both caregivers and children. Evaluation of pain and the identification of CP patients who are at high risk of experiencing pain is worthwhile, as these individuals have difficulty in verbalizing pain due to their cognitive problems, although they are at risk of experiencing pain due to chronic physical problems, such as spasticity and contracture, as well as interventions for complicated medical problems
An analysis of controlled foreign company rules, the OECD’s pillar two and developing countries
No full textThe author, in this article, discusses how developing countries could be affected by the developments initiated by the OECD by asking the following two research questions. How would developing countries be affected by adapting controlled foreign company regulations and Pillar Two? Are the interests of developing countries protected at all
An analysis of controlled foreign company rules, the OECD’s pillar two and developing countries
No full textThe author, in this article, discusses how developing countries could be affected by the developments initiated by the OECD by asking the following two research questions. How would developing countries be affected by adapting controlled foreign company regulations and Pillar Two? Are the interests of developing countries protected at all
Effects of posttreatment with alkaline copper quat and copper azole on the mechanical properties of wood-based composites
No full textWOS: 000323824200014The static bending strengths, modulus of rupture, and modulus of elasticity of 5 commercial wood-based composites [softwood plywood (SWP), hardwood plywood (HWP), medium density fiber-board (MDF), oriented strand board (OSB), and particleboard (PB)] were measured after a postmanufacture treatment of vacuum-impregnation with alkaline copper quat (ACQ) and copper azole (CA) (target retentions: 0.65, 1.30, and 2.60 kg m(-3) for ACQ; 0.25, 0.50, and 1.0 kg m(-3) for CA). Of the composites tested, SWP exceptionally sustained no damage to its bending strengths, regardless of preservative types and retentions. Others (HWP, MDF, OSB, and PB) were necessarily affected to some degree by posttreatments. In accordance with the dimensional stability and resistance to biological attacks, of the posttreated composites, SWP seems most suitable and implemental for posttreatment when the appropriate selection of treatment concentrations and schedules is made.Japan Society for the Promotion of Science through RISH Laboratories in Kyoto University [P07171]The author extends his appreciation to the Japan Society for the Promotion of Science for supporting this study through a postdoctoral fellowship grant (P07171) at RISH Laboratories in Kyoto University and to the late Kunio Tsunoda, who gave moral support in the beginning of the study
An alternative ice cream production for diabetic patients
No full textIn this research, the ice cream samples for diabetic patients were produced using maltitol (maltisorb and lycasin), sorbitol, and high fructose corn syrup and analyzed as physical, chemical and sensory attributes. The ice cream samples to which sucrose was added were used as control. The acidity of samples ranged from 5.37 SH to 6.94 SH. The sucrose-added samples had the highest viscosity value of 6.02 Pa.s, the lycasin syrup-added ones were found to have the lowest viscosity of 2.35 Pa.s. The lowest overrun ratio (26.30 %) was found in sorbitol syrup-added samples, the highest one (37.52%) in the samples containing sucrose. Although the amount of glucose in sucrose-added ice cream samples was as high as 381 mg/100 g, that of sorbitol and maltitol in the same samples was as low as 104 and 108 mg/100 g, respectively. Because panelists preferred the maltitol-added ice cream samples to the others, maltitol could be used in ice cream production for diabetic patients
The diagnostic utility of the Wechsler Intelligence Scale for Children-Fourth Edition (WISC-IV) in identification of gifted children
No full textAccurate assessment and early identification of gifted children is of great importance in terms of providing them with educational programs tailored for their abilities in specific areas. Individually administered intelligence tests are widely used to identify gifted children, and an above-average level of intellectual capacity is generally accepted as the main criterion for giftedness. This study aimed to investigate the utility of the Turkish version of the Wechsler Intelligence Scale for Children-Fourth Edition (WISC-IV) to distinguish gifted children from non-gifted children. For this purpose, 201 gifted children and 201 non-gifted children were included in the study. To be able to determine the predictive power of the WISC-IV index and subtest scores, logistic regression analyses were performed. Results indicated that the Perceptual Reasoning Index, Working Memory Index, and Processing Speed Index scores (except Verbal Comprehension Index score), and all subtest scores significantly predicted giftedness. Furthermore, correct classification rates among gifted children were 93% for index scores and 97% for subtest scores. The findings of this study suggest that intelligence scores obtained from the WISC-IV have a diagnostic utility and provide valid and reliable results in identifying gifted children
PLATELET TO LYMPHOCYTE RATIO ON ADMISSION AND PROGNOSIS IN PATIENTS WITH ACUTE CARDIOGENIC PULMONARY EDEMA
No full textBackground: Acute heart failure is a heterogenous syndrome defined by a number of factors, such as its physiopathology, clinical picture, time of onset, and relation to acute coronary syndrome. Acute cardiogenic pulmonary edema (ACPE) constitutes approximately 10-20% of acute heart failure syndromes, and it is the most dramatic symptom of left heart failure. Platelet to lymphocyte ratio (PLR) is a relatively novel inflammatory marker that can be utilized for prognosis in various disease processes. Objective: In this study, we investigated the value of the PLR for the prediction of mortality in patients with ACPE. Methods: A total of 115 patients hospitalized with a diagnosis of ACPE were included in this study. The patients were divided into tertile groups according to their PLR values: high (PLR > 194.97), medium (98.3-194.97), and low tertile (PLR < 98.3). Results: We compared the PLR groups for in-hospital mortality and total mortality after discharge. Multivariate Cox regression analysis showed that PLR was independently associated with total mortality (hazard ratio 5.657; 95% confidence interval 2.467-12.969; p < 0.001). Survival analysis using the Kaplan-Meier curve showed that the high-PLR group had a significantly higher mortality rate than the other groups. Conclusions: We showed an association between high PLR and mortality in patients with ACPE. PLR, together with other inflammatory markers and clinical findings, may be used as an adjunctive parameter for the stratification of mortality risk, hospitalization, or discharge criteria scoring. (C) 2018 Elsevier Inc. All rights reserved
- …
