1,354,246 research outputs found
Classicismo e poesia di corte al tempo di Carlo di Borbone, in Celato G.-Chirico M.L., La poesia encomiastica latina per Carlo di Borbone
No full textThis paper has two main purposes: providing a general overview of the eulogistic production for Charles of Bourbon, highliting its literary genres and authors, the most frequently used topics, the models of reference and, furthermore, the public use of rethoric, the restoration of Classicism, and the influence of Vico and Gravina’s theories in eloquence. In the second part the study focuses on some carmina composed for Charles of Bourbon by Alessio Simmaco Mazzocchi, the most distinguished Neapolitan intellectual of the first half of the XVIII century. The study analizes their content, the occasion on which they were composed, and their quotations of ancient authors. Mazzocchi constantly promoted Charles of Bourbon’s reforms. Nevertheless, this aspect of his production and his role as a poet laureate has never been adequately considered yet
Agli albori della moderna storiografia sulla Campania antica: l'Apparato alle Antichità di Capua di Camillo Pellegrino
No full textThe paper’s aim is to present some aspects concerning life and works of the Capuan antiquarian Camillo Pellegrino Junior (1598-1663). Some influent nineteenth century scholars, in particular Wilamowitz and Mommsen, criticized south Italian antiquarian research and often considered its method as unreliable and philologically inaccurate. As a result of these critiques, Neapolitan antiquarianism has been forgotten for centuries, until the modern studies reconsidered its importance. The article argues that the previous scholar’s criticism can not be applied to Camillo Pellegrino, which could be considered as a pioneer in modern historiographical production about Ancient Campania and as a predecessor of Muratori’s studies
L'ingresso di Annibale in Campania: riconsiderando un'emendazione a Polibio (III 92, 1) di Camillo Pellegrino
No full textNasonis vincere decus. Da Ovidio a Claudiano: gli studi di Nicolaus Heinsius sugli auctores latini
No full textDefinito da Bentley "poetarum Latinorum unicus sospitator" e considerato da Housman uno dei più geniali latinisti di tutti i tempi, Nicolaus Heinsius (1620-1681) continua a suscitare ammirazione soprattutto per la straordinaria abilità congetturale dispiegata nelle sue numerose edizioni di autori antichi. L’attività ecdotica di Heinsius è stata variamente descritta dalla critica come ‘tardo-umanistica’, ‘pre-lachmanniana’ o ‘post-lachmanniana’, formule che solo in parte definiscono l’essenza della sua poliedrica filologia. Gli studi raccolti in questo volume presentano alcuni aspetti della figura di Heinsius da una prospettiva storico-critica, inquadrandone l’opera nel processo di sviluppo della disciplina antichistica. La trattazione è corredata da un’ampia appendice documentaria, contenente una centuria di "epistulae mutuae" tra Heinsius, il noto antiquario Cassiano dal Pozzo (1588-1657) ed altri corrispondenti italiani
Claudio FERONE, Opuscula, a cura di Angelo Russi, 'Gervasiana', Gerni Editore, San Severo 2013, voll.I (2 t.)-III, pp. 436; 170; 286; 333
No full textDaniel Heinsius editore del Nuovo Testamento
No full textAccording to Henk Jan de Jonge, the second edition of the Elzevir’s New Testament, known as the Textus Receptus and published in Leiden in 1633 with the preface of Daniel Heinsius, was edited by Jeremias Hoelzlin. de Jonge also considered that none other than Daniel Heinsius had responsibilities in preparing the first edition of the Elzevir’s New Testament of 1624, but there was no clear evidence to prove this. A letter sent by Nicolaus Heinsius to his father Daniel in 1641 from England seems to confirm that Daniel Heinsius did indeed prepare the edition of 1624
Diagnostic work-up and therapeutic options in management of pediatric status epilepticus
No full textBACKGROUND:
Status epilepticus (SE) is a life-threatening neurologic disorder comprising prolonged and unremitting crisis, and two or more series of seizures without complete intercritical recovery.
DATA SOURCES:
We reviewed the literature through a Pubmed/Medline research using key words including status epilepticus, antiepileptic drugs and children, in order to revise and compare international/national protocols and to examine pediatric guidelines in SE management.
RESULTS:
Neurologic impairment and SE etiology seem to be the most independent risks for mortality. A deep semiologic evaluation is essential to addressing diagnostic work-up. Ematochemical parameters, plasma levels of antiepileptic drugs and clinically oriented toxic/metabolic screening should be mandatory for investigating both causes and effects of SE. Electroencephalography is clearly helpful to characterize focal from generalized SE and to distinguish epileptic events from pseudoseizures, and it is deal to find nonconvulsive SE. Neuroimaging techniques could detect epileptogenic lesions (such as cortical malformations, tumors, demyelinating disorders or strokes) but are common in practice to find negative or controversial results. Pharmacologic management can be essentially arranged in three stages: benzodiazepines for early SE (lasting less than 30 minutes), phenytoin/fosphenytoin, phenobarbital, valproate, levetiracetam or lacosamide for established SE (30-90 minutes), and anesthetics for refractory SE (more than 90 minutes).
CONCLUSIONS:
Status epilepticus is the most common neurologic emergency in childhood. A systematic diagnostic work-up and a three steps based therapeutic approach is required at this age
A diagnostic algorithm for the evaluation of early onset genetic-metabolic epileptic encephalopathies
No full textEarly onset epileptic encephalopathies represent a struggling challenge in neurological clinical practice, mostly in infants and very young children, partly due to an unclear and still debated cathegorization. In this scenario genetic and metabolic epileptic encephalopathies play a central role, with new entries still needing an arrangement. In this Paper we present a brief overview on genes, metabolic disorders and syndromes picturing the pathogenesis of genetic and metabolic epileptic encephalopathies with onset under one year of age. These forms will be classified, according to a combined clinical and genetic-metabolic criterion, into two main groups including seizures as prominent/unique symptom and seizures associated with a syndromic phenotype. Starting from this classification we suggest a possible simplified diagnostic algorithm, discussing main decision making nodes in practical patients management. The aim of the proposed algorithm is to guide through metabolic and molecular-genetic work up and to clarify "where" and "what" to search in biochemical, electroencephalographic and neuroimaging investigations. (C) 2011 European Paediatric Neurology Society. Published by Elsevier Ltd. All rights reserved
Espressione immunoistochimica del recettore per il gnrh nelle cellule normali e negli adenomi dell'ipofisi
No full textSEVERE SELF-INJURIOUS BEHAVIORS AS MAIN CLINICAL MANIFESTATION OF A NEW FORM OF CEREBRAL FOLATE DEFICIENCY
No full textIntroduction: Cerebral Folate Deficiency (CFD) is a severe neurometabolic encephalopathy associated with low levels of 5-methyltetrahydrofolate (5MTHF) in cerebrospinal fluid (CSF) and normal systemic folate metabolism. We report on a new clinical variant of CFD. Case report: A 6 years old male with intellectual disability, hypotonia, acquired microcephaly and without epilepsy and autistic features came to our attention because of severe recurrent self-injuring behaviors (SIBs) (hitting his head by hands or feet with a rapid, stereotyped, compulsive limb movements), which were triggered by selective environmental changes or frustrating novelties. MRI was normal. He had a low cerebrospinal fluid (CSF) concentration of 5-methyltetrahydrofolate (5MTHF), increased CSF biopterin and normal values of peripheral blood folate. Mutations in Folate receptor 1 gene and the production of folate receptor blocking/binding autoantibodies were excluded. MTHFR gene sequencing and DHPR enzyme activity were normal. Lesch Nyhann, Rett and Angelman syndromes were excluded. Folate supplementation restored almost completely CSF folate without influencing either biopterin and biogenic amine concentrations or SIBs. Conclusions: Developmental delay, mental disability, acquired microcephaly, severe SIBs and undetectable 5MTHF in CSF with remarkable increase of biopterin are all hallmarks of this new condition associated to CFD. Epilepsy and autism spectrum disorder are notably absent
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