1,720,981 research outputs found
Cerebral ventricular size in diagnostic subtypes of schizophrenia and in schizophreniform disorder
No full textCT scan abnormalities in schizophreniform and in schizophrenic spectrum personality disorder
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Cerebral ventricular size in schizophrenic spectrum disorders: relationship to clinical, neuropsychological and immunogenetic variables
No full textFurther studies on the major histocompatibility complex as a genetic marker for schizophrenia.
No full textOur results seem to indicate the existence of a locus in the major histocompatibity complex (MHC) region, correlated to schizophrenic illness and strictly linked to the loci HL-A and MLR. The associations found between these last loci and the disease can probably be explained by a linkage disequilibrium or a selective pressure between the allelles of the three loci. Our results also indicate that the genetic systems investigated may be useful diagnostically as a genetic marker for schizophrenia. But the real meaning of their relationships to the illness has to be further investigated
Virological and immunological study of schizophrenic patients in relation to CT scan abnormality.
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Etiopathogenetic Hypotheses of Schizophrenia: The impact of epidemiological, biochemical and neuromorphological studies.
No full textThe HLA system and the clinical response to treatment with chlorpromazine.
No full textA group of 33 schizophrenic patients were typed for HLA-SD antigens and their qualitative clinical responses to chlorpromazine therapy determined. A highly significant positive correlation was found between response to chlorpromazine and HLA-AI positive, while HLA-A2 positive subjects showed a significant negative correlation to chlorpromazine treatment. In a second group of 17 patients the clinical response to chlorpromazine were evaluated quantitatively, by WPRS, in HLA-AI positive and HLA-AI negative patients. There were no pre-treatment differences in the scores. After treatment the scores of positive patients were significantly lower, indicating that they responded to a greater degree. Since the frequency of HLA-AI in hebephrenic patients is higher than that in other schizophrenics this may explain our earlier finding that hebephrenics, as a group, respond better to chlorpromazine than do other schizophrenics
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