1,720,984 research outputs found
Post-surgical pre-implantar bone defects regeneration in pediatric patients with sodium hyaluronate and amino acids
No full textThis study was designed to evaluate whether a sterile gel formulation of sodium hyaluronate and amino acids Gly-Pro-Leu-Lys (AMINOGAM®) is effective in accelerating post-surgical and pre-implantar bone defects regeneration in pediatric patients. We evaluated different healing in 28 bone defects, divided in 2 groups: test group treated with intracavitary intraoperative filling of gel and control group without gel. Outcomes were evaluated by clinical and radiographic follow-up through grey scale densitometry. Defects treatment after bone healing in both groups was completed with histological pre-implantar examination through trephine drill and insertion of implants. Clinical and radiographic evaluations of the implants were performed at 12 months after functional loading.
Soft tissues outcomes in test group show immediate haemostatic effect, pain and swelling decrease and infective complication dejection (0%) compared to control group (6%). Gel reduces removing stitches time at 6 days in test group compared to 14 days in control group.
Hard tissues outcomes show faster healing time: 30% difference between ossification level in test and control group at 2 months. The difference decrease in following months until 3% at 12 months. Pre-implantar bone specimen get with 2,5mm trephine drill shows a more dense and mature lamellar bone with twisted fiber and different calcification level allowing early implant insertion at 30-45 days in test group compared to 60 days in control group
DENTINOGENESIS IMPERFECTA IN CHILDREN WITH OSTEOGENESIS IMPERFECTA: A CLINICAL AND ULTRASTRUCTURAL STUDY.
No full textAim. The aim of this study was to assess the correlation between osteogenesis imperfecta (OI) and dentinogenesis imperfecta (DI) from both a clinical and histological point of view, particularly clarifying the structural and ultrastructural dentine changes.
Design. Sixteen children (6-12 years aged) with diagnosis of OI were examined for dental alterations referable to DI. For each patient, the OI type (I,III, or IV) was recorded. Extracted or normally exfoliated primary teeth were subjected to a histological examination (to both optical microscopy and confocal laser-scanning microscopy).
Results A total of ten patients had abnormal discolourations referable to DI: four patients were affected by OI type I, three patients by OI type III, and three patients by OI type IV. The discolourations, yellow/brown or opalescent grey, colud not be related to the different types of OI. Histological exam of primary teeth showed severe pathological change in the dentin, structured into four different layers. A collagen defect due to odontoblast dysfunction was theorized to be on the base of the histological changes.
Conclusion. There is no correlation between the type of OI and the type of discolouration. The underlying dentinal defect seems to be related to an odontoblast dysfunction
Syndromic (NBCCS) and sporadic Keratocystic Odontogenic Tumour: comparison of histopathological features in Confocal Laser Scanning Microscopy
No full textSleep-disordered breathing in a sample of 495 children in Southern Italy.
No full textAbstract
AIM: Our objective was to investigate the occurrence of sleep-related breathing disturbances in a large cohort of school-aged children in Southern Italy, and to evaluate the association with anthropometric data and clinical findings of oropharynx and nasal airways. Study design: A two-phase cross-sectional study was conducted with children from schools in Turi, Italy.
MATERIALS AND METHODS: A screening phase aimed to identify symptomatic children and clinical data from a cohort of 495 children by a self-administered questionnaire, and an instrumental phase for the definition of sleep-related disorders and clinical analysis of oral status were performed. According to the answers, children were classified into 3 groups: habitual snorers, occasional snorers, and non-snorers. All habitual snoring children underwent a polysomnographic home evaluation, and those with oxygen desaturation index (ODI) > 2 were considered for nocturnal polygraphic monitoring (NPM). Children with apnoea/ hypopnea index (AHI) > 3 received a diagnosis of obstructive sleep apnoea syndrome (OSAS). Moreover, a complete oral examination was performed.
RESULTS: A total of 436 questionnaires (response rate: 88.08%) were returned and scored (202 M, 234 F; Mean age ± Standard deviation: 6.2 ± 1.8); 18 children (4%) were identified as habitual snorers, 140 children (32%) were identified as occasional snorers, and 278 children (64%) were identified as non-snorers. The percentage of female children who were habitual snorers was higher than the percentage of male children (4.7% vs 3.6%). Habitual snorers had significantly more nighttime symptoms. OSAS was diagnosed in 2 children by NPM. A statistically significant association between snoring, cross-bite, open-bite and increased over-jet was found.
CONCLUSION: Habitual snoring and OSAS are significant problems for children and may be associated with diurnal symptoms. The presence of malocclusion increases the likelihood of sleep-related breathing disturbances
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