1,720,962 research outputs found
Suicidal inactivation of human cytochrome P450 by carbon tetrachloride in vitro and prediction of risk in vivo
Suicidal inactivation of human cytochrome P-450 by carbon tetrachloride and halothane in vitro.
Reductive activation of halothane by human haemoglobin results in the modification of the prosthetic haem.
The paper reports the mechanism of the original observation that human haemoglobin may reductively activate the anaesthetic halothane, resulting in the irreversible inactivation of the prosthetic haem moiety
Suicidal inactivation of haemoproteins by reductive metabolites of halomethanes: a structure-activity relationship study.
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