1,720,972 research outputs found
Process for Transforming Teicoplanin Factor A2 Component 1 into Teicoplanin Factor A2 Component 3
No full textThe present invention refers to a process for transforming teicoplanin factor A2 component 1 into teicoplanin factor A2 component 3 by means of a chemical reaction which includes the catalytical hydrogenation of the substrate
Chemical Process for Preparing Antibiotic L 17392 (Deglucoteicoplanin) and its Salts
No full textThe present invention is directed to a chemical process for preparing antibiotic L 17392 (deglucoteicoplanin) and its salts with bases and acids by submitting a teicoplanin compound or a teicoplanin-like compound to controlled strong acidic hydrolysis conditions
Chemical Process for Preparing L 17392 (Deglucoteicoplanin) and its Salts
No full textThe present invention is directed to a chemical process for preparing antibiotic L 17392 (deglucoteicoplanin) and its salts with bases and acids by submitting a teicoplanin compound or a teicoplanin-like compound to controlled strong acidic hydrolysis conditions
Process for Preparing Antibiotic L 17392 (Deglucoteicoplanin)
No full textProcess for preparing antibiotic L 17392 by catalytically hydrogenating a deglucoteicoplanin ester of formula (I), wherein A, B and Z represent hydrogen atoms, R represents benzyl or substituted benzyl, wherein the phenyl group is substituted with at least a substituent selected from chloro, bromo, fluoro, nitro, (C1-C3)alkyl, (C1-C3)alkoxy and the like, with the exclusion of the tri-nitro phenyl group, or acid addition salts thereof, to catalytic hydrogenolysis in the presence of a poisoned hydrogenation catalyst at a temperature from 10C to 40C and a pressure between ambient pressure and 5 atm, in an inert organic solvent preferably in the presence of a mineral acid
Chemical Process for Preparing Antibiotic L 17054
No full textThe present invention is directed to a chemical process for preparing the antibiotic substance denominated antibiotic L 17054 and its pharmaceutically acceptable salts by selectively hydrolizing teicoplanin or a factor or compound thereof with a concentrated strong organic acid
Synthesis and In Vitro Biological Evaluation of N- (5-Amino-1-b-D-ribofuranosyl-1H-imidazol-4-yl)carbonyl -3-(hydroxynitrosamino)-L-alanine (L-Alanosine AICO Ribonucleoside)
No full textGlycopeptide Antibiotic L 17054
No full textThe present invention is directed to the essentially pure preparation of an antibiotic substance arbitrarily designated antibiotic L 17054. This antibiotic substance is obtained from the known antibiotic substance named teicoplanin (formerly teichomycin) by chemical treatment. The new compound and the pharmaceutically acceptable salts possess antimicrobial activity
Ester Derivatives of Antibiotic L 17046
No full textThe present invention is directed to ester derivatives at the carboxylic function of the glycopeptidic antibiotic substance called antibiotic L 17046 with antimicrobial activity mainly against gram-positive bacteria
Antibiotic L 17046 and Process for Preparing it
No full textThe present invention is directed to a new antibiotic substance arbitrarily denominated antibiotic L 17046. The antibiotic substance is obtained from the known antibiotic substance called teicoplanin (formerly teichomycin) by chemical treatment. The new compound possesses antimicrobial activity especially against gram-positive bacteria
Carboxylic Acid Ester Derivatives of Deglucoteicoplanin
No full textThe present invention is directed to carboxylic acid esters of deglucoteicoplanin, i.e. of the aglycon moiety of the antibiotic teicoplanin. The compounds of the invention are conveniently prepared either by deglucoteicoplanin or by any of the glycopeptides of the teicoplanin group, such as teicoplanin itself, one of its components, antibiotic L 17054 and antibiotic L 17046
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