24 research outputs found
Ariel - Volume 3 Number 2
No full textEditors
Richard J. Bonanno
Robin A. Edwards
Associate Editors
Steven Ager
Stephen Flynn
Tom Williams
Lay-out Editor
Eugenia Miller
Contributing Editors
Paul Bialas
Milton Packer
Robert Breckenridge
Lynne Porter
Mark Pearlman
Terry Burt
Mike Leo
Editors Emeritus
Delvyn C. Case, Jr.
Paul M. Fernhof
Ariel - Volume 2 Number 7
No full textEditors
Richard J. Bonanno
Robin A. Edwards
Associate Editors
Steven Ager
Stephen Flynn
Shep Dickman
Tom Williams
Lay-out Editor
Eugenia Miller
Contributing Editors
Michael J. Blecker
W. Cherry Light
James J. Nocon
Lynne Porter
Editors Emeritus
Delvyn C. Case, Jr.
Paul M. Fernhof
Ariel - Volume 2 Number 8
No full textEditors
Richard J. Bonanno
Robin A. Edwards
Associate Editors
Steven Ager
Stephen Flynn
Shep Dickman
Tom Williams
Lay-out Editor
Eugenia Miller
Contributing Editors
Michael J. Blecker
Milton Packe
James J. Nocon
Lynne Porter
Editors Emeritus
Delvyn C. Case, Jr.
Paul M. Fernhof
Ariel - Volume 2 Number 5
No full textEditors
Delvyn C. Case, Jr.
Paul M. Fernhoff
News Editors
Richard Bonanno
Robin A. Edwards
Features Editors
Stephen P. Flynn
Steven A. Ager
Lay-Out Editor
Carol Dolinskas
Contributing Editors
Michael J. Blecker
W. Cherry Light
Eugenia Miller
Lin Sey Edwards
Jack Guralnik
Tom Williams
James Noco
Ariel - Volume 3 Number 1
No full textEditors
Richard J. Bonanno
Robin A. Edwards
Associate Editors
Steven Ager
Stephen Flynn
Tom Williams
Lay-out Editor
Eugenia Miller
Contributing Editors
Michael J. Blecker
Milton Parker
James J. Nocon
Lynne Porter
Editors Emeritus
Delvyn C. Case, Jr.
Paul M. Fernhof
Ariel - Volume 2 Number 3
No full textEditors
Delvyn C. Case, Jr.
Paul M. Fernhoff
News Editors
Richard Bonanno
Daniel B. Gould
Robin A. Edwards
Lay-Out Editor
Carol Dolinskas
Sports Editor
James J. Nocon
Contributing Editors
Michael J. Blecker
Lin Sey Edwards
Jack Guralnik
W. Cherry Light
Features Editor
Steven A. Ager
Donald A. Bergman
Stephen P. Flynn
Business Manager
Nick Greg
Ariel - Volume 2 Number 6
No full textEditors
Richard J. Bonanno
Robin A. Edwards
Associate Editors
Steven Ager
Stephen Flynn
Shep Dickman
Tom Williams
Lay-out Editor
Eugenia Miller
Contributing Editors
Michael J. Blecker
W. Cherry Light
James J. Nocon
Lynne Porter
Editors Emeritus
Delvyn C. Case, Jr.
Paul M. Fernhof
Phase II Study of Intravenous Idarubicin in Unfavorable Non-Hodgkin\u27s Lymphoma
No full textIdarubicin, a new analogue of daunorubicin, was administered i.v. at a dose of 15 mg/m2 to 31 previously treated patients with unfavorable non-Hodgkin\u27s lymphoma. Clinical characteristics included median age, 69 years; performance status, 1; and prior chemotherapeutic regimens, 1. Twenty of the patients were relapsing after prior therapy and 11 were refractory, 29 had received prior anthracycline or anthra-cenedione. Responses were observed in 43% of patient (3 complete remission and 10 partial remission) with a median duration of 10+ months (2-29+ months). Idarubicin was well tolerated with nonhematological toxicities (nausea/vomiting, mucositis, and anorexia) seen in \u3c50% of patients. Median hematological values during the first cycle for this dosage included WBC, 1,300/mm3; platelets, 129,000/mm3; and hemoglobin, 10.9 mg/dl. With dose escalation, hematological toxicity was dose limiting. Symptomatic cardiac toxicity was observed in one patient who had received maximum dose doxorubicin and radiotherapy. Median values for the cardiac ejection fraction during the full course of therapy for the entire group of patients were 0.62 (initial) and 0.60 (final). Idarubicin in i.v. form is an active drug in previously treated patients with unfavorable non-Hodgkin\u27s lymphoma
Ariel - Volume 3 Number 4
No full textEditors
Richard J. Bonanno
Robin A. Edwards
Associate Editors
Steven Ager
Tom Williams
Lay-out Editor
Eugenia Miller
Contributing Editors
Paul Bialas
Robert Breckenridge
Lynne Porter
David Jacoby
Terry Burt
Mark Pearlman
Michael Leo
Mike LeWitt
Editors Emeritus
Delvyn C. Case, Jr.
Paul M. Fernhof
Ariel - Volume 3 Number 5
No full textEditors
Richard J. Bonanno
Robin A. Edwards
Associate Editors
Steven Ager
Tom Williams
Lay-out Editor
Eugenia Miller
Contributing Editors
Paul Bialas
Robert Breckenridge
Lynne Porter
David Jacoby
Terry Burt
Mark Pearlman
Michael Leo
Mike LeWitt
Editors Emeritus
Delvyn C. Case., Jr.
Paul M. Fernhof
