86,568 research outputs found
Transcatheter aortic valve replacement and chronic kidney disease: Close friends or sworn enemies?
No full textsystem for contrast media volume reduction in percutaneous procedures: “Make kidney safe again”
No full textFake News Spreaders Profiling through Behavioural Analysis Notebook for PAN at CLEF 2020
No full textThe growth of social media and the people interconnection led to the digitalization of communication. Nowadays the most influential politicians or scientific communicators use the media to disseminate news or decisions. However, such communications media can be used maliciously to spread the so-called fake-news in order to polarise public opinion or to deny scientific theories. It is therefore important to develop intelligent and accurate techniques in order to identify the spreading of fake-news. In this paper, we describes the methodology regarding our participation in the PAN@CLEF Profiling Fake News Spreaders on Twitter competition. We propose a supervised Machine-Learning (ML) based framework to profile fake-news spreaders. Our method relies on the combination of Big Five personality and stylometric features. Finally, we evaluate our framework detection capabilities and performance with different ML models on a tweeter dataset in both English and Spanish languages
Transcatheter closure of complex iatrogenic ventricular septal defect: A case report
No full textBackground: Iatrogenic membranous ventricular septal defects (VSDs) are rare complications of cardiothoracic surgery, such as septal myectomy for hypertrophic obstructive cardiomyopathy (HOCM). Transcatheter closure is considered an appealing alternative to surgery, given the increased mortality associated with repeated surgical procedures, but reports are extremely limited. Case summary: We herein report the case of a 63-year-old woman with HOCM who underwent successful percutaneous closure of an iatrogenic VSD after septal myectomy. Two percutaneous techniques are discussed, namely the 'muscular anchoring' and the 'buddy wire delivery', aimed at increasing support and providing stability to the system during percutaneous intervention. Discussion: Transcatheter closure represents an attractive minimally invasive approach for the management of symptomatic iatrogenic VSDs. The new techniques described could help operators to cross tortuous and tunnelled defects and to deploy closure devices in case of complex VSD anatomy
CT angiography versus colour-Doppler US in acute dissection ofthe vertebral artery.
No full textPurpose. Conventional digital subtraction angiography (DSA) still
represents the criterion standard for the diagnosis of vertebral
artery dissection (VAD), but the main drawbacks of this technique
include invasiveness, patient discomfort and risk of complications.
We evaluated the potential of multidetector computed tomography
angiography (CTA) as a noninvasive tool providing highresolution
images of the arterial lumen and wall by comparing the
diagnostic accuracy of CTA and colour-Doppler ultrasonography
(CDUS) in detecting acute VAD.
Materials and methods. We retrospectively reviewed 15 cases of
VAD in 15 patients (five men and ten women, age range 28–58
years) who came to our attention between August 2001 and
September 2005. The diagnosis was made on the basis of
appropriate clinical presentation, absence of atherosclerotic
disease in the cerebrovascular circulation and evidence of
distinctive CT features, which were subsequently confirmed by
conventional angiography used as reference standard. All patients
with a clinical suspicion of VAD underwent CDUS of the neck
vessels prior to CTA. Accuracy, sensitivity and specificity of
CDUS and CTA were expressed as percentages of agreement with
the reference angiographic procedure. Interreader concordance for
detection of VAD by CTA was calculated with the Cohen K value.
Results. The CDUS examinations revealed ten out of 15 VAD,
with a sensitivity of 66%, a specificity of 60%, a positive
predictive value of 55.5% and a negative predictive value of
70.5%. In five cases, CDUS revealed nonspecific wall and flow
alterations; in eight patients, high resistance obstructive flow;
and in two patients, intimal flap with demonstration of the true and
false lumen. CTA enabled the correct identification of all 15
VAD. The reported sensitivity, specificity, positive predictive
value and negative predictive value were 100%, 95%, 93.7%
and 100%, respectively. With regard to localisation of VAD,
CTA showed 100% correlation with DSA. The differences in CTA
and CDUS sensitivity (100% vs 66%), specificity (95% vs 60%),
and overall diagnostic accuracy (97% vs 62.8%), assessed by
cross tabulations and compared by using the McNemar’s
two-sided test, were significant (p<0.05).
Conclusions. Multidetector CTA is a sensitive technique for the
diagnosis of VAD. Used as a complement to unenhanced brain
CT, it has the advantage of being readily available and easy to
perform
Population genetics and the role of dispersal barriers in the Antarctic springtail Kaylathalia klovstadi (Collembola, Isotomidae)
Get PDFIsolation and extreme environmental conditions have significantly impacted terrestrial invertebrate biodiversity in Antarctica, with glacial cycles further limiting animal diversity to a small number of species. Among these, springtails are relatively abundant, though their taxonomic diversity remains low. Antarctic glaciers may serve as major dispersal barriers, leading to high levels of genetic divergence among isolated populations. In Victoria Land (continental Antarctica), the Tucker Glacier has been proposed as an example of such a barrier; however, different species or taxa may respond differently to the same geographical features. In this study, we tested whether geographic distance, major glacier tongues, and seawater channels influence the distribution of Kaylathalia klovstadi (Collembola; Isotomidae) in Northern Victoria Land. We conducted mitochondrial DNA haplotype analysis on fragments of cytochrome c oxidase subunit 1 (cox1) and ATP synthase 6 (atp6) in 62 individuals from six K. klovstadi populations. Our analysis provides new insights into the genetic diversity and distribution patterns of K. klovstadi by incorporating additional sampling sites, specimens, and molecular markers. We challenge previous views regarding the role of the Tucker Glacier as a significant physical barrier to springtail dispersal in Northern Victoria Land. Our findings suggest that the impact of physical barriers on the genetic diversity of Antarctic Collembola, including the species studied here, requires a more careful evaluation
Variations on the Author
Get PDF“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
[Newspaper Clipping: Author Claims Evidence of Second JFK Assassin #1]
No full textNewspaper article titled "Author Claims Evidence of Second JFK Assassin." The article states that author Richard J. Whalen concluded "that there is circumstantial evidence to support the theory of a second assassin in the shooting of President John F. Kennedy.
Measurement of systemic resistances in aortic regurgitation.
No full textPeripheral resistance is usually measured by dividing mean aortic pressure by mean aortic flow. This statement holds true as long as resistance is constant throughout the heart cycle. This is not the case in aortic regurgitation, because during diastole, but not in systole, a conduit is opened to blood flow through the regurgitating valve. Peripheral resistance was measured in 11 patients with aortic regurgitation and in 23 normal subjects by solving for Ri in the "windkessel" equation. We compared this resistance (R1) with that measured by standard methods (RES). In normal subjects, R1 and RES are almost identical [R1 = 0.96 (RES) +/- 0.12, r = .95], while in aortic regurgitation there is no correlation [R1 = 0.64 (RES) +/- 1.4, r = 0.2]. RES in normal subjects is increased with respect to RES in aortic regurgitation (32 vs 22, p = 0.0019), while R1 in aortic regurgitation is decreased compared to both R1 and RES in normal subjects (13.5 vs 21 and 22, p = 0.0063). The difference between R1 and RES in aortic regurgitation is related to the regurgitating volume. Compliance, calculated by assuming a monoexponential diastolic aortic pressure decay, is markedly decreased in aortic insufficiency, while it is increased if it is calculated by dividing the time constant of aortic pressure decay by R1. Thus, in severe aortic regurgitation peripheral resistance is usually less than normal, and standard methods of measurement fail to detect this fact. Correct evaluation of resistance and compliance may be useful to evaluate ventriculoarterial coupling and to titrate vasodilator therapy in this disease
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