4,208 research outputs found

    Submacular Choroidal Thickness Evaluation After Laser Photocoagulation For Diabetic Retinopathy

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    Abstract Purpose:To evaluate subfoveal choroidal thickness before and after laser photocoagulation in diabetic retinopathy (DR) visualized by Spectral Domain OCT (SDOCT). Methods:A total of 15 patients affected by DR were involved in this prospective interventional study. Inclusion criteria comprehend DR complicated by significant macular edema or retinal ischemia. Exclusion criteria include media opacities, other vascular or inflammatory retinal pathologies. Seven patients received scatter laser photocoagulation for proliferative DR and eight patients focal or laser grid photocoagulation for diabetic macular edema. By means of a SDOCT (OTI-OPKO, Toronto, Canada) experienced operators measured choroidal thickness in subfoveal area and 3mm away from the fovea in nasal and temporal region, after imaging enhancement procedures. Clinical measurements were performed at baseline, at day 7 and day 14 after laser treatment. Statistical analysis was performed to compare the results. Results:Choroidal and retinal thickness OCT measurements were performed to all subjects on scheduled visits. Mean choroidal thickness at baseline was respectively 250,7 ± 60,6μm in subfoveal region, 166,4 ± 63μm nasal to fovea and 241,4 ± 66μm temporal to fovea; at day 7 was 280,8 ± 76μm (p=0.01), 180,8 ± 63μm (p>0.05) and 239,2 ± 67μm (p>0.05); at day 15, mean choroidal thickness was 246,3 ± 62μm (p=0.03), 171,8 ± 65μm (p>0.05) and 240 ± 68,8μm (p>0.05). Retinal macular thickness measured underwent to an overall variation during follow up from a baseline value of 286,4±60,01μm to 323±75,9μm at day 7 (p=0.03) and to 310,9±62,01μm at day 15 (p>0.05). Conclusions:Our study showed at day 7 a statistically significant increase of choroidal thickness only in subfoveal region, subsequently decreased at day 14. This observation was associated to a significant increase of retinal thickness at day 7. These observations underline and confirm the involvement of choroidal tissue on different traumatic and inflammatory vitreoretinal events, as well as the role of new SDOCT to better evaluate and measure choroidal structure

    Vitreous Substitutes: The Present and the Future.

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    Vitreoretinal surgery has advanced in numerous directions during recent years. The removal of the vitreous body is one of the main characteristics of this surgical procedure. Several molecules have been tested in the past to fill the vitreous cavity and to mimic its functions. We here review the currently available vitreous substitutes, focusing on their molecular properties and functions, together with their adverse effects. Afterwards we describe the characteristics of the ideal vitreous substitute. The challenges facing every ophthalmology researcher are to reach a long-term intraocular permanence of vitreous substitute with total inertness of the molecule injected and the control of inflammatory reactions. We report new polymers with gelification characteristics and smart hydrogels representing the future of vitreoretinal surgery. Finally, we describe the current studies on vitreous regeneration and cell cultures to create new intraocular gels with optimal biocompatibility and rheological properties

    Yeast metabolism in fresh and frozen dough : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Food Technology at Massey University, Palmerston North, New Zealand

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    Author also known as SM LovedayFresh bakery products have a very short shelf life, which limits the extent to which manufacturing can be centralised. Frozen doughs are relatively stable and can be manufactured in large volumes, distributed and baked on-demand at the point of sale or consumption. With appropriate formulation and processing a shelf life of several months can be achieved.Shelf life is limited by a decline in proofing rate after thawing, which is attributed to a) the dough losing its ability to retain gas and b) insufficient gas production, i.e. yeast activity. The loss of shelf life is accelerated by delays between mixing and freezing, which allow yeast cells the chance to ferment carbohydrates.This work examined the reasons for insufficient gas production after thawing frozen dough and the effect of pre-freezing fermentation on shelf life. Literature data on yeast metabolite dynamics in fermenting dough were incomplete. In particular there were few data on the accumulation of ethanol, a major fermentation end product which can be injurious to yeast.Doughs were prepared in a domestic breadmaker using compressed yeast from a local manufacturer and analysed for glucose, fructose, sucrose, maltose and ethanol. Gas production after thawing declined within 48 hours of frozen storage. This was accelerated by 30 or 90 minutes of fermentation at 30;C prior to freezing.Sucrose was rapidly hydrolysed and yeast consumed glucose in preference to fructose. Maltose was not consumed while other sugars remained. Ethanol, accumulated from consumption of glucose and fructose, was produced in approximately equal amounts to CO2, indicating that yeast cells metabolised reductively.Glucose uptake in fermenting dough followed simple hyperbolic kinetics and fructose uptake was competitively inhibited by glucose. Mathematical modelling indicated that diffusion of sugars and ethanol in dough occurred quickly enough to eliminate solute gradients brought about by yeast metabolism

    Converting SrI <sub>2</sub> :Eu <sup>2+</sup> into a near infrared scintillator by Sm <sup>2+</sup> co-doping

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    The luminescence and scintillation properties of SrI 2 single crystals doped with 5% Eu 2+ and 0.05%, 0.2% and 0.5% Sm 2+ are evaluated. X-ray excited and photoluminescence measurements show energy transfer from excited Eu 2+ ions to Sm 2+ ions. At a concentration of 0.5% Sm 2+ , the luminescence consists almost entirely of 740 nm emission from Sm 2+ 5d-4f transitions. Co-doping SrI 2 :5% Eu 2+ with Sm 2+ provides a novel method to bypass the self-absorption problem encountered in large SrI 2 :Eu 2+ crystals and, at the same time, provides a unique near-infrared emitting scintillator with a light yield of approximately 40,000 photons/MeV. Accepted Author ManuscriptRST/Fundamental Aspects of Materials and EnergyRST/Luminescence Material

    'Laws 'Needefull in Later to be Abrogated': Intersex and the Sources of Christian Theology

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    This is the author accepted manuscript. The final version is available from Palgrave Macmillan via the DOI in this record

    Introduction: Troubling Bodies?

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    This is the author accepted manuscript. The final version is available from Palgrave Macmillan via the DOI in this record

    Intrafullerene electron transfers in Sm-containing metallofullerenes: Sm@C-2n (74 &lt;= 2n &lt;= 84)

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    The electronic properties of Sm-containing metallofullerenes, Sm@C-74, Sm@C-76 (I, II), Sm@C-78, Sm@C-80, Sm@C-82 (I, II, III) and Sm@C-84 (I, II, III), are characterized by UV-Vis-NIR absorption spectroscopy and electron energy-loss spectroscopy (EELS). the UV-Vis-NIR absorption spectra of Sm@C-74, Sm@C-80, Sm@C-82 (I, II, III) and Sm@C-84 (I, II) are quite similar to those of the corresponding Ca, Sr, Ba, Eu, Tm, Yb-based metallofullerenes. In contrast, the absorption spectra of Sm@C-76 (I, II), Sm@C-78 and Sm@C-84(III) show a novel feature: the onset for Sm@C-78 is observed similar to 2600 nm, which corresponds to a small band gap (similar to0.5 eV). Furthermore, the oxidation states of Sm atom in the various fullerene cages are investigated by EELS, which reveals that the Sm atom takes +2 oxidation state in the fullerene cages. A probable rationale for the tendency to have the Sm2+ state is presented based on a simple thermochemical cycle model. (C) 2001 by Elsevier Science Inc.http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000168906500014&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=8e1609b174ce4e31116a60747a720701Biochemical Research MethodsBiochemistry &amp; Molecular BiologyComputer Science, Interdisciplinary ApplicationsCrystallographyMathematical &amp; Computational BiologySCI(E)EI30ARTICLE2244-2511

    beta-decay spectroscopy of neutron-rich Sm-160,Sm-161,Sm-162 isotopes

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    Neutron-rich Sm-160,Sm-161,Sm-162 isotopes have been populated at the RIBF, RIKEN via beta decay for the first time. beta-coincident gamma rays were observed in all three isotopes including gamma rays from the isomeric decay of Sm-160 and Sm-162. The isomers in Sm-160 and Sm-162 have previously been observed but have been populated via beta decay for the first time. The isomeric state in Sm-162 is assigned a 4(-) nu 7/2(+)[633]circle times nu 1/2(-)[521] configuration based on the decay pattern. The level schemes of Sm-160 and Sm-162 are presented. The ground states in the parent nuclei Pm-160 and Pm-162 are both assigned a 6(-) nu 7/2(+)[633]circle times pi 5/2(-)[532] configuration based on the population of states in the daughter nuclei. Blocked BCS calculations were performed to further investigate the spin-parities of the ground states in Pm-160, Pm-161, and Pm-162, and the isomeric state in Sm-162.CPCI-S(ISTP)[email protected]

    Discovering the Similarities between SM Communities and Other Organizations

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    The current research study is comparing and contrasting the demographic diversity of Sadomasochist (SM) organizations and other community organizations by surveying an SM organization and a non-SM organization. A confidential online survey was used to collect data. Fourteen general questions were asked: age, gender, sexual orientation, relationship status, number of children, ethnicity, highest level of education completed, employment, hours worked, income, religious affiliation, personality, infidelity and self esteem. Data was analyzed using Levene\u27s test and t-tests. Relationship status and religion were two differences between the SM group and the non SM group. The author discusses limitations and future directions of this study
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