1,720,989 research outputs found
Helicobacter pylori L-asparaginase: A Novel Bacterial Antigen that May Contribute to Infection Detection
Helicobacter pylori is responsible for gastric inflammation and for an increased risk of cancer development in humans. Several bacterial antigens contribute to stimulate the immune system, but their relative role has not yet been defined. H. pylori (strain CCUG) type II L-asparaginase (L-ASNase) induces an immune response in mice. To verify if an immune response could also be detected in humans, sera positive (n=11) or negative (n=11), respectively, to H. pylori according to a commercial test were assayed for their reactivity towards purified H. pylori L-ASNase. Among positive samples, 8/11 (72%) were positive to L-ASNase. We conclude that H. pylori L-ASNase is immunogenic in humans and contributes to the generation of the antibody response induced by the bacterium
Comparative analysis of the neuronal activation and cardiovascular effects of nitroglycerin, sodium nitroprusside and l-arginime
Molecular Cloning and Characterisation of Helicobacter Pylori L-Asparaginase: A Cytotoxic Factor with Potential Biomedical Applications
Perturbation of intercellular signalling: modeling approaches and characterization of the experimental system
Investigation of signaling perturbation in cells exposed at low doses of ionizing radiation
Systems Radiation Biology: un possibile strumento per l’indagine dei meccanismi dell’effetto bystander?
The complex dynamics of proteic signaling after different stimuli: an example of response after ionizing radiation
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