655 research outputs found

    F.R. TOMLINSON: MENS EN WETENSKAPLIKE

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    The 1996 F.R. Tomlinson Memorial Lecture was delivered on 23rd May 1996 in Bloemfontein. The author, Prof D.J.G. Smith, chose the subject : F.R. Tomlinson: Man and ScientistTeaching/Communication/Extension/Profession,

    F.R. Falconer's House

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    Photograph - A man in the backyard of F.R. Falconer's house, Athabasca, Alberta. Across the lane is the nurse's residence, later owned by Mrs. Dan Bilid

    Clarithromycin in the Management of Chronic Rhinosinusitis: Preliminary Results of a Possible Its New Use

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    The aim of this study is to evaluate the efficacy and safety of prolonged therapy with low-dose clarithromycin in patients with chronic rhinosinusitis with polyps (CRSwP) after endoscopic sinus surgery (ESS). A total of 10 patients with CRSwP were identified and subjected to bilateral ESS. In post-operative patients they were treated with nasal wash with saline solution and steroid sprays (beclomethasone). During follow-up, after 30–40 days after the operation (M = 35.4 SD = +4.33), patients reported a worsening of symptoms with onset of nasal obstruction; reduction/loss of smell; headache; onset of viscous secretions and therefore all patients continued therapy with saline nasal irrigation, topical steroid therapy and started macrolide (clarithromycin 500 mg/pill: 1 pill/day for 3 days a week for 1 month). 22-item SinoNasal Outcome Test (SNOT-22) and a score to the endoscopic evaluation (endoscopic appearance score, EAS) before and after treatment were performed to evaluate efficacy of treatment. The results of the SNOT-22 and EAS showed statistically significant improvements (p < 0.05) for some parameters such as: the need to blow nose, sneezing, hyposmia, viscous mucous secretions about the SNOT-22 and reduction of secretions and edema of the nasal mucosa about the EAS. The preliminary results of our study show that the low-dose clarithromycin for a period of 1 month can improve patient complaints with CRSwP not only through the antibacterial properties but also for the immunomodulatory characteristics

    The endoscopic diving technique in pituitary and cranial base surgery: technical note

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    OBJECTIVE: We used the diving technique to go beyond mere visualization of the surgical field and used it as an important step in removing the lesion itself, improving the optical field, and optimizing visualization with a dynamic fluid film lens. Likewise, having extended endoscopic endonasal surgery to the entire base of the skull and in particular to the sinus cavity, "diving surgery" has proven to be effective in visualizing and dissecting more extended tumors. METHODS: We performed diving surgery in more than 350 surgical procedures to remove lesions in the sellar, sinus cavity, and clival regions. Intrasellar hydroscopy was performed in all cases to check that the lesion was removed completely and to gently dissect any intracavitary residual tumoral tissue. Diving surgery can be performed in the sellar cavity, in the cavernous sinus, and at the level of the posterior cranial fossa in the cavity obtained after clivectomy. RESULTS: The hydrodissection and continuous flushing of the sellar cavity, together with better control of bleeding, allow the surgeon to perform piecemeal removal of the lesion with direct control of the cleavage plane and tumor residue and avoid blind curettage near the pituitary gland. This technique is particularly useful in identifying small infiltrations of the cavernous sinus and in checking the integrity of the pituitary stalk when instruments are introduced into the sella. CONCLUSION: Diving surgery is a useful step in dealing with minor complications that can occur during endonasal endoscopic surgical procedures

    The minimally invasive sinus surgery technique

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    The minimally invasive sinus technique, (MIST) is different from minimally invasive sinus surgery. MIST implies a treatment philosophy and surgical model that is quite different from functional endoscopic sinus surgery (FESS). The goals of this article are to discuss the origins of functional sinus surgery as it relates to the evolution of FESS and MIST, define MIST as a philosophy and surgical model, discuss treatment of surgical sinus disease, and challenge the rationale for our departure from Messerklinger's "functional" concepts into what will be referred to as "contemporary FESS. " Many authors address the reduced revision rate (compared with FESS) following initial intervention with MIST, the potential to markedly reduce the rate of intranasal synechiae, and the reduction in immediate postoperative morbidity

    Forms of judaism in writings of F.R. Kraus, František Kafka, Hana Bělohradská and J.R. Pick

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    Téma této práce zní Podoby židovství v dílech F.R. Krause, Františka Kafky, Hany Bělohradské a J.R. Picka. Soustředila jsem se na méně známé české autory, kteří se ve své tvorbě věnovali tématu židovství. Jedná se o texty související s 2. světovou válkou. V úvodu je nastíněn stručný přehled o působení Židů na našem území, následuje představení zvolené čtveřice autorů. Hlavním cílem bylo přiblížit a rozebrat vybraná díla a v závěru shrnout jejich odlišné a podobné znaky. Současně byly tyto texty zařazeny do kontextu české prózy s tematikou okupace.Katedra českého jazyka a literaturyObhájenoThe theme of this bachelor work is called Forms of judaism in writings of F.R. Kraus, František Kafka, Hana Bělohradská and J.R. Pick. In this thesis the author tried to concentrate on a few less-known Czech writers, who devoted their writing to the fate of Jews during the Second World War. In the first part of this work the author outlined the influence of the Jewish etnic group on the population of our country, with the aim to gain orientation in the historical backgound of that time. Next the author analysed the texts of selected books with the Jewish theme from different points of view and in the end of her work compared the books she used. In the closing of this work there is a contextual classification of the mentioned books into the category of works with the topic of occupation, from the end of the Second World War until today

    Endonasal approaches to the sellar and parasellar regions: closure techniques using biomaterials

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    PURPOSE: We reviewed the clinical outcomes resulting from various closure techniques used following endoscopic endonasal surgery for lesions in the sellar and parasellar regions. We compared our current closure technique, which uses a biological matrix of native equine collagen (TissuDura) fixed with fibrin sealant (Tisseel), with the technique we employed previously, using autologous materials, in order to assess the comparative efficacy and tolerability of both methods over the medium- to long-term. METHODS: A review was conducted of all cases of endonasal endoscopic intervention carried out in our institution between 1997 and 2007. Operations performed between January 1st 1997 and December 31st 2003 involved a sellar closure technique using autologous materials, either alone or supported by fibrin sealant. From January 1st 2004, sellar reconstruction techniques involving resorbable heterologous materials were used in the closure phases. Post-operatively, clinico-endoscopic assessments took place at 15 days, 1, 3, and 6 months and yearly thereafter, supplemented by magnetic resonance imaging (MRI) scanning at 3 months and annually. RESULTS: Between January 1st 1997 and December 31st 2003, 79 operations were performed in which the sellar closure technique involved the use of autologous materials. Between January 1st 2004 and January 1st 2008, 125 operations were performed in which biomaterials were used for sellar closure. The incidence of complications (fluid fistula) was 2.5% in the autologous materials closure group and 1.6% in the biomaterials closure group. The most marked difference between the two approaches was seen at 1-month follow-up, when restoration of mucociliary transport in the sphenoidal sinus and physiological functionality of the nasal mucosa and paranasal sinuses were observed to be superior in the biomaterials patient cohort. CONCLUSIONS: The development of biomaterials for closure of the sellar floor offers a viable alternative to traditional techniques using autologous materials

    Guide to the management of complications in endoscopic sinus surgery (ESS)

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    Endoscopic sinus surgery (ESS) is one of the most commonly performed procedures in otolaryngology. ESS complications should be distinguished in minor and major based on the treatment they need and the permanent sequelae they can cause. Over the years it has gone from an incidence of complications in endoscopic surgery of 8% for the major and 21% for the minor to a percentage of 0-1.5% and 1.1-20.8%, respectively. This is due to the considerable diffusion of the technique with a progressive increase over the years of the surgical experience but their presence help to educate otolaryngologists and patients about complication rates in ESS in a modern context. A complication occurs when injuries to anatomical structures defined in the literature "risk areas" are created. The surgeon must know and identify these areas because these are important land mark that guide our interventions respecting the anatomical boundaries. The aim of this chapter is to describe principle complications and their managment

    Organization of shallow cumulus clouds

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    HPCI User Report for the project Organization of shallow cumulus clouds on the Fugaku supercomputer.Green Open Access added to TU Delft Institutional Repository 'You share, we take care!' - Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.Atmospheric Remote Sensin

    Tumours of Nasal Septum: A Retrospective Study of 32 Patients

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    Objective: Tumours of the nasal septum are a rare and heterogeneous group of lesions in the sinonasal tract. The management of the different lesions of this site is debated. The aim of this study is to share our experience on a rare clinical condition and stimulate other centres to publish theirs. Methods: We retrospectively analysed the databases of sinonasal tumours treated at the Sections of Otolaryngology (ENT) of two University Hospitals (Palermo and Genova) between 2012 and 2020. Results: From the two databases, a cohort of 32 patients with tumours of nasal septum were selected. All patients underwent an endoscopic examination. Large tumours underwent preoperative computed tomography (CT) scan without contrast medium. In 22 (68.7%) cases, the preoperative radiologic evaluation also included magnetic resonance imaging (MRI) with gado-linium to obtain a better differentiation of the lesions and study the vascular pattern. All the large lesions were biopsied under endoscopic guidance using local anaesthesia; the same approach was used to remove the tumours and their attachment with safe resection margins. Conclusions: While malignant lesions require an excision of the mass with resection of all layers of the nasal septum, benign lesions must be typed according to histological considerations in order to plan the most appropriate type of surgical resection
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