1,723,941 research outputs found
Ricorda e splendi. Scritti e discorsi di Angelo Ermanno Cammarata sulla questione di Trieste
No full textIl saggio ricostruisce l'attività politico-giuridica di Angelo Ermanno Cammarata, rettore dell'Università di Trieste nei primi anni del Governo militare alleato (1945-1954), concentrandosi in particolare sulla contestualizzazione e sulla valutazione critica della tesi di diritto internazionale a cui è legato il suo nome, volta a sostenere la mai cessata sovranità italiana sulle zone ricomprese dal Trattato di pace del 1947 nel Territorio libero di Trieste
Humoral and cellular immunity in spontaneous feline infectious peritonitis
No full textHUMORAL AND CELLULAR IMMUNITY IN SPONTANEOUS FELINE INFECTIOUS PERITONITIS
Paltrinieri S.*, Cammarata Parodi M.**, Cammarata G.**, Comazzi S.*
* Istituto di Patologia Generale Veterinaria - Milano - Italy; ** Istituto di Anatomia Patologica Veterinaria e Patologia Aviare - Milano - Italy
Vascular lesions in Feline Infectious Peritonitis (FIP) are thought to be caused by a type III hypersenstivty reaction, while histology of the granulomas suggest a type IV hypersensitivity. To further investigate the pathogenesis of the disease we analized some aspects of humoral and cellular immunity in FIP. Haematology, antibody titers and protein electrophoresis in serum and in effusions from 48 FIP affected cats were studied. The results were compared with those of 20 healthy cats. The distribution of the immune cell and of the virus in FIP lesions were also studied by immunohistochemistry using antibodes against myelomonocytic (MAC387), and lymphoid (CD3, CD4 and CD8 for T-cells and IgM and IgG for B-cells) antigens.
Seropositive animals (antibody titer>1:100) were present either among the FIP infected cats (73%) either among the healthy cats (72%). FIP infected cats had neutrophilic leukocytosis (P>0.05), lymphopenia (P<0.05) and hyperglobulinemia (P<0.01) with increased 2 (P<0.05) and globulins (P<0.001). Hypergammaglobulinemia was not related to the antibody titers, suggesting the presence of other proteins with motility (e.g. complement fractions such as C1q). These changes were found either in effusive or in non effusive FIP. The electrophoretic pattern of the effusions was always similar to those of the corresponding serum. Antibody titers higher than those of the corresponding serum were often detected in the effusions. Immunohistochemical findings were not related to the antibody titers, but they were related to the histology of the lesions. In cellular foci of FIP lesions many virus-infected macrophages and few lymphocytes, mainly CD4+ve, were found. Extracellular viral and myelomonocytic antigen were also detectable in the foci with intercellular necrosis. Only few FIPV-infected cells were present at the periphery of the larger necrotic foci: in these lesions MAC387+ve cells were mainly neutrophils, with many MAC387-ve macrophages, may be due to their activated state: a mild number of lymphocytes, with an increasing percentage of CD8+ve cells were present. Lymphocytes were more abundant when cellular foci and FIP infected macrophages were centered around neoformed vessels. IgM and IgG exposing B-cells were always few and scattered.
In conclusion the simoultaneous analysis of body fluids and of the cellular composition of the lesions showed a complex immune status, on which type III and type IV hypersenstivty could cohexist
Detection of Feline coronaviruses (FCoV) in circulating monocytes by direct immunofluorescence
No full textDETECTION OF FELINE CORONAVIRUSES (FCoV) IN CIRCULATING MONOCYTES BY DIRECT IMMUNOFLUORESCENCE
Paltrinieri S.*, Cammarata Parodi M.**, Cammarata G.**, Masotti A.***
*Istituto di Patologia Generale Veterinaria - Milano; **Istituto di Anatomia Patologica Veterinaria e Patologia Aviare - Milano; *** Private DVM - Milano
In the pathogenesis of feline infectious peritonitis (FIP) spread of the coronaviruses (FIPV) through the body is ensured by circulating monocytes. Feline enteric coronaviruses (FeCV) seem to be unable to pass through epithelial cells. If Feline Coronaviruses (FCoV) are found in circulating monocytes this would differentiate the FIPV from the other coronaviruses of the cats. Therefore, we examined 62 cats without FIP-related symptoms, most of which were positive for circulating anti-FCoV antibodies, measured by an indirect fluorescent antibody test (IFA), from 3 different catteries (10, 31 and 21 cats), in which their first cases of FIP were recently diagnosed following exposure to the infection by contact with infected cats. In a small sample of blood from each cat, after the haematological analysis, red blood cells were lysed hypotonically. On the blood leukocytes obtained by cytocentrifugation direct immunofluorescence anti-FCoV (DIF) was performed, and the results were analyzed statistically to calculate the prevalences of the positivity for the catteries and to exclude the influence of pathophysiological and methodological variables. No haematological abnormalities were observed in cats from any of the 3 catteries. The prevalence of the FCoV positivity in blood monocytes was 22%. The age and the sex of the cats, the charachteristics of the blood sample (amount of blood, total and differential number of leukocytes, number of erythrocytes) and of the isolated cell populations (purity and recovery), and the presence of aspecific symptoms (moderate rhinitis, enteritis) were unrelated to positivity, while a risk factor such as contact with other infected catteries was highly significant (P<0.01). All the DIF+ve cats were also IFA+ve for circulating anti-FCoV antibodies: anti-FCoV titers were found also in some of the DIF -ve cats maybe due to a cross-reactivity with FeCV. The detection of FCoV on blood monocytes should be considered an useful tool to complete the clinico-serological diagnosis of FIP. Our results also seem to confirm the possibility of using the DIF test to detect the spread of the FCoV into the monocytes
Advanced ultrasonic structural monitoring of waveguides
No full textThe support of the University of Pittsburgh to Mr. Cammarata is acknowledged. The third and
fourth authors acknowledge the support of the Korea Science and Engineering Foundation
(M20703000015-07N0300-01510) and Korea Research Foundation (D00462)
Sul pensiero filosofico-giuridico di A.E. Cammarata. Dalla legalità alla giustizia nel formalismo giuridico
No full textIl pensiero filosofico-giuridico di Angelo Ermanno Cammarata consente di cogliere due momenti, tra un ‘primo’ e un ‘secondo’ Cammarata: il ‘primo’ è concentrato in un percorso per lo più speculativo alla teoria generale del diritto, con attenzione alle forme della logica e alle teorie del diritto, ma già con una ‘tendenza’, che è intensione, ad un panorama filosofico dei temi del diritto. Il ‘secondo’ Cammarata, invece, inizia a delinearsi quando viene pubblicato, quale ultima voce del XVII volume dell’Enciclopedia del diritto, il fondamentale studio sul Formalismo giuridico, nel quale si apprende, partendo si’ dall’immanenza ma marcando una originale riflessione sul momento del ‘pensiero’, che non vi sono limiti esterni a questo e che «tra la soluzione del caso come problema di legalità e la soluzione del caso individuale non potrà mai eliminarsi uno scarto». Il pensiero filosofico-giuridico di Cammarata costituicse un momento essenziale alla speculazione della filosofia del diritto, con la centralità del ‘momento umano’ come ‘problema’, tra la ‘volontà’, come dimensione che consente di distinguere tra le ‘alternative’, e la scelta: senza queste due dimensioni «la libertà del soggetto non avrebbe senso», perdendosi ogni riferimento alla giuridicità, in una equivoca pluralità di direzioni. Dalla scelta e dalla volontà di iniziativa, temi centrali in Cammarata, si arriva alla ‘elezione di uno scopo del comportamento’, chiarendo così la dimensione giuridico-esistenziale
Cammarata, Angelina
No full textCentro Asturiano membership record of Angelina Cammarata; Socio Number: 1694.https://digitalcommons.usf.edu/asturiano_membership/1738/thumbnail.jp
Mitchell in Italia
No full textL'articolo, postfazione al libro Pictorial Turn. Saggi di cultura visuale, mette in evidenza e collega gli studi italiani che hanno subito l'influenza delle teorizzazioni di WJT Mitchell e che hanno contribuito a creare la corrente italiana della visual culture attraverso discipline differenti come le letterature comparate, l'estetica, la filosofia, gli studi sul cinema, persino l'architettura
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