1,720,972 research outputs found
The role of clinical observation: Red flag 4-cardiomyopathies and sensorineural hearing loss
No full textThe role of clinical observation: Red flag 1-cardiomyopathies and skeletal muscle involvement
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The role of clinical observation: Red flag 7-syndromic and multi-system cardiomyopathies
No full textThe role of clinical observation: Red flag 5-right ventricular involvement, arrhythmogenic right ventricular cardiomyopathy and associated phenotypes
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Correlation between histomorphometric findings and endomyocardial biopsy and clinical findings in idiopathic dilated cardiomyopathy
No full textMultivariate analysis was used to analyze the morphometric data of endomyocardial biopsies (area, perimeter and minor diameter) of myocardial cells obtained at light microscopy by a computerized approach with 16 clinical parameters and prognosis in 52 patients with idiopathic dilated cardiomyopathy. The best morphometric parameter was "area" (R2 = 0.47). A positive correlation was found with age (p less than 0.02), interval between first symptoms and diagnosis (p less than 0.02), left ventricular end-diastolic volume (p less than 0.02), cardiac index (p less than 0.05) and echocardiographic end-diastolic diameter (p less than 0.1). A negative correlation was found with prognosis (p less than 0.02), ejection fraction (p less than 0.02), shortening fraction (p less than 0.05), echocardiographic end-systolic diameter (p less than 0.06) and mitral regurgitation presence (p less than 0.1). The parameters that provided no correlation were New York Heart Association class, left ventricular end-diastolic pressure, right atrial pressure, cardiothoracic ratio, presence or absence of heart failure, fever or alcohol intake. These findings suggest that endomyocardial biopsy may provide prognostic information and confirm clinical diagnosis
The role of clinical observation: red flag 8 - Cardiomyopathies in the first year of life and pediatric cardiomyopathies.
No full textPediatric carduiomyopathies [CMPs] are complex and present challenges to both cardiologists and pediatricians. The incidence of pediatric CMPs is significantly higher in the first year of life than in older age. All types of CMP may be present in early childhood. The most frequent type is dilated cardiomyopathy [DCM], while familial hypetrophic cardiomyopathy [HCM] caused by contractile protein abnormalities usually develops, at least in some series, after the first decade of life
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