991 research outputs found
Exploiting Domain Knowledge in Making Delegation Decisions
No full text@inproceedings{conf/admi/EmeleNSP11, added-at = {2011-12-19T00:00:00.000+0100}, author = {Emele, Chukwuemeka David and Norman, Timothy J. and Sensoy, Murat and Parsons, Simon}, biburl = {http://www.bibsonomy.org/bibtex/20a08b683088443f1fd36d6ef28bf6615/dblp}, booktitle = {ADMI}, crossref = {conf/admi/2011}, editor = {Cao, Longbing and Bazzan, Ana L. C. and Symeonidis, Andreas L. and Gorodetsky, Vladimir and Weiss, Gerhard and Yu, Philip S.}, ee = {http://dx.doi.org/10.1007/978-3-642-27609-5_9}, interhash = {1d7e7f8554e8bdb3d43c32e02aeabcec}, intrahash = {0a08b683088443f1fd36d6ef28bf6615}, isbn = {978-3-642-27608-8}, keywords = {dblp}, pages = {117-131}, publisher = {Springer}, series = {Lecture Notes in Computer Science}, timestamp = {2011-12-19T00:00:00.000+0100}, title = {Exploiting Domain Knowledge in Making Delegation Decisions.}, url = {http://dblp.uni-trier.de/db/conf/admi/admi2011.html#EmeleNSP11}, volume = 7103, year = 2011
Evaluating Research Impact through Open Access to Scholarly Communication
No full textScientific research is a competitive business – in order to secure funding, promotion and tenure researchers must demonstrate their work has impact in their field. To maximise impact researchers undertake high priority research, aim to get results first, and publish in the highest impact journals. The Internet now presents a new opportunity to the scholarly author seeking higher impact: s/he can now make their work instantly accessible on the Web through author self-archiving. This growing body of open access literature (coupled with new publishing models that make journals available for-free to the reader) maximises research impact by maximising the number of people who can read it, and making it available sooner. Open access also provides a new opportunity for bibliometric research. This thesis describes the relatively recent phenomenon of open access to research literature, tools that were built to collect and analyse that literature, and the results of analyses of the effect of open access and its effect on author behaviour. It shows that articles self-archived by authors receive between 50-250% more citations, that rapid pre-printing on the Web has dramatically reduced the peak citation rate from over a year to virtually instant and how citation-impact – now widely used for evaluation – can be expanded to include a new web metric of download impact
Domain constants of injectivity.
No full textLet f be a locally injective mapping of a simply connected hyperbolic domain D into \bar\doubc. Under what circumstances is f injective? We assign norms to f in such a way that if f is sufficiently small, then f is injective. Using these norms we associate domain constants of injectivity to D. We consider the cases where f is meromorphic and locally K-quasiconformal. For f meromorphic let S\sb{\rm f} denote the Schwarzian derivative and let \rho\sb{\rm D} denote the density of the Poincare metric in D. The inner radius of univalence (D) is defined as the supremum of the numbers a 0 such that \vert\rm S\sb{f}(z)\vert a\rho\rm\sb{D}(z)\sp2 for all z D is a sufficient condition for f to be injective. We define normal circular triangles and show that (D) = 2k\sp2 if D is a normal circular triangle whose smallest angle is k. Using this result we show that if D is a regular n-sided polygon, then (D) = 2 . For locally K-quasiconformal mappings we define (D,K) as the supremum of the numbers b with the property that if log J\sb{\rm f}\Vert\sb\* \leq b, then f is injective; when no such constants b exist, we set (D,K) = 0. Here \Vert\cdot\Vert\sb\* denotes the BMO norm in D. Then we define K(D) as the supremum of the numbers K for which (D,K) 0. It is known that K(D) 1 if and only if D is a quasidisk, and that K(D) 2 for all D, with equality if D is a disk. We prove that K(D) = 2 also when D = z: z 1, Re (z) cos(k) for k 1/7. For this we show that D has a length-area property which we call the crosscut property. We prove also that domains with this property are convex and are K-quasidisks where K is bounded by an absolute constant.PhDMathematicsPure SciencesUniversity of Michigan, Horace H. Rackham School of Graduate Studieshttp://deepblue.lib.umich.edu/bitstream/2027.42/128207/2/8821554.pd
Using whole exome sequencing to investigate the genetic bases of lysosomal storage diseases of unknown etiology
No full textLysosomes are membrane-bound, acidic eukaryotic cellular organelles that play important roles in the degradation of macromolecules. Mutations that cause the loss of lysosomal protein function can lead to a group of disorders categorized as the lysosomal storage diseases (LSDs). Suspicion of LSD is frequently based on clinical and pathologic findings, but in some cases, the underlying genetic and biochemical defects remain unknown. Here, we performed whole exome sequencing (WES) on 14 suspected LSD cases to evaluate the feasibility of using WES for identifying causal mutations. By examining 2,157 candidate genes potentially associated with lysosomal function, we identified eight variants in five genes as candidate disease-causing variants in four individuals. These included both known and novel mutations. Variants were corroborated by targeted sequencing and, when possible, functional assays. In addition, we identified nonsense mutations in two individuals in genes that are not known to have lysosomal function. However, mutations in these genes could have resulted in phenotypes that were diagnosed as LSDs. This study demonstrates that WES can be used to identify causal mutations in suspected LSD cases. We also demonstrate cases where a confounding clinical phenotype may potentially reflect more than one lysosomal protein defect.Peer reviewe
Music for classical guitar by South African composers : a historical survey, notes on selected works and a general catalogue
No full textIncludes abstract.Includes bibliographical references (leaves 296-309).This is the first comprehensive investigation of music for, or including, the classical guitar by South African composers. The focus of this research has been, firstly, to uncover as much of the repertoire as possible, and, secondly, to collate, study, catalogue and report on the information. A brief historical survey of the guitar in South Africa provides the context within which this study was conducted. The primary sources of quantitative data collection were through the archival catalogues of the South African Music Rights Organisation and through personal contact with guitarists, composers and guitar teachers. Other sources consulted were publishers, broadcasting corporations, recording companies, libraries and the internet. The body of the dissertation comprises biographical sketches, background notes, analyses and technical notes on 17 selected solo and chamber works dating from 1947 to 2007 by some of South Africa's most prominent composers and guitaristcomposers. The repertoire ranges in style from the traditional and ethnically inspired to the experimental and abstract. As this is an empirical survey, each selected entry includes details on instrumentation, duration, level of difficulty, number of pages, scordatura, commissions or requests, sources or publishers, premières and recordings. A biography of each composer is provided as well as background notes which offer an overview of the selected work. The notes discuss historical, cultural, musical and extra-musical influences, and frequently include references to interview material. The commentaries on the selected works, with musical examples, include an analytical component describing structure, form, stylistic and compositional elements, while the technical observations include performance suggestions and a grading for each work
Analysis of watersheds and river systems: short course
No full textShort course: Analysis of Watersheds and River Systems, Session I and II, held on May 28-June 1, 1979 and June 4-June 8, 1979 at Colorado State University, Fort Collins, Colorado.Speakers: Dr. E. V. Richardson, Dr. David Duttweiller, Mr. Lee Mulkey, Dr. Stanley A. Schumm, Dr. Daryl B. Simons, Dr. Ross Carder.Includes bibliographical references.This short course is designed for individuals dealing with the analysis of watersheds and rivers. Practical applications concerning physical processes will be emphasized.Chapter 1. General introduction / Daryl B. Simons and Ruh-Ming Li -- Chapter 2. Introduction to watershed and river analysis / Daryl B. Simons and Ruh-Ming Li -- Chapter 3. Physical processes governing response of watersheds and rivers / Daryl B. Simons, Timothy J. Ward and Ruh-Ming Li -- Chapter 4. Sediment transport / H. W. Shen -- Chapter 5. Alluvial bed roughness / H. W. Shen -- Chapter 6. Overview of flood routing methods / Ruh-Ming Li and V. Miguel Ponce -- Chapter 7. Water routing and yield from watersheds, Part I and II / Ruh-Ming Li, Daryl B. Simons, and Kenneth G. Eggert -- Chapter 8. Water routing in rivers / Yung-Hai Chen -- Chapter 9. Stage discharge relations / Robert K. Simons, Ruh-Ming Li, and Daryl B. Simons -- Chapter 10. Watershed sediment yield / Ruh-Ming Li, Daryl B. Simons, and Timothy J. Ward -- Chapter 11. Unsteady sediment routing models in rivers / Yung-Hai Chen and Daryl B. Simons -- Chapter 12. Known discharge sediment routing / Glenn O. Brown and Ruh-Ming Li -- Chapter 13. Landslide potential delineation / Timothy J. Ward, Ruh-Ming Li, and Daryl B. Simons -- Chapter 14. Application of Kalman filtering in watershed and river analysis / Nguyen Duong -- Chapter 15. Handheld calculator programs for analysis / Kenneth G. Eggert, Ruh-Ming Li, and Daryl B. Simons -- Chapter 16. Overview of case studies and data management / Daryl B. Simons, Ruh-Ming Li, and Nguyen Duong -- Chapter 17. Canal and channel design and river response analysis / Daryl B. Simons, Ruh-Ming Li, and Yung-Hai Chen -- Chapter 18. Degradation and aggradation analysis / Ruh-Ming Li and Daryl B. Simons -- Chapter 19. Watershed best management analysis / Ruh-Ming Li, Timothy J. Ward, and Daryl B. Simons -- Chapter 20. Large river basin analysis: Yazoo River Sedimentation Study / Daryl B. Simons and Ruh-Ming Li
Introduction to property theory - the fundamental theorems
No full textThe market system consists of a price mechanism, built on the foundation of a system of property, and contract. In many developing, and transition economies, the market system functions poorly. In many cases, if not most, the malfunctioning is not simply in the price system (for example, anti-competitive activities), but in the underlying property system (such as contracts being breached, and externalities in the sense of transfers not covered by contracts). Economic theory tends to take the functioning of the system of property, and contract for granted, and focuses on the operation of the price mechanism. Property theory focuses on the underlying system of property, and contract. In this paper, the author inaugurates the mathematical treatment of property theory.In contrast with earlier work in"law and economics", and the"new institutional economics", this approach uses principles drawn from jurisprudence, and does not attempt to reduce"law"to"economics"in the sense of efficiency considerations, such as the minimization of transaction costs. The main results are the two fundamental theorems of property theory that are analogous to the two fundamental theorems of price theory that, in essence, state that: 1) A competitive equilibrium is Pareto optimal. 2) Given a Pareto optimal state, there exists a set of prices such, that a competitive equilibrium at those prices would realize that Pareto optimal state.Environmental Economics&Policies,Labor Policies,Banks&Banking Reform,Municipal Housing and Land,Economic Theory&Research,Environmental Economics&Policies,Banks&Banking Reform,Economic Theory&Research,Municipal Housing and Land,Land and Real Estate Development
Photosynthesis-inspired device architectures for organic photovoltaics
No full textThesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 2010.This electronic version was submitted by the student author. The certified thesis is available in the Institute Archives and Special Collections.Cataloged from student submitted PDF version of thesis.Includes bibliographical references (p. 153-166).Organic semiconductor photovoltaics offer a promising route to low-cost, scalable, emissions-free electricity generation. However, achieving higher power conversion efficiencies is critical before these devices can play a larger role in our future energy generation landscape. Organic photovoltaic devices are currently limited by two primary challenges: (1) a trade-off between light absorption and exciton diffusion and (2) low open-circuit voltage due to charge recombination at the donor-acceptor interface. In this work, we demonstrate two new device architectures inspired by photosynthesis that aim to overcome these two challenges. First, we overcome the trade-off between light absorption and exciton diffusion by introducing an external light absorbing antenna layer. We model energy transfer from the antenna to the charge generating layers via surface plasmon polariton modes in the interfacial thin silver contact and via radiation into waveguide modes. We experimentally demonstrate devices with both single layer antennas and strongly absorbing resonant cavity antennas. We measure energy transfer efficiency from the antenna layer to the PV active layers as high as 51±10%. We discuss structural design criteria and describe ideal antenna material characteristics. Second, we reduce charge transfer state recombination in organic photovoltaics by inserting a thin interfacial layer at the donor-acceptor interface. The thin interfacial layer creates a cascade energy structure that destabilizes the Coulombically bound charge transfer state formed immediately following exciton dissociation. We nd the optimal interfacial layer thickness to be approximately 1.5 nm. In CuPc/C₆₀ devices, under simulated solar illumination the short-circuit current increased 34%, the open-circuit voltage increased 33%, and the power conversion eciency increased 49%. Thin interfacial layers can also be used to study the physics of exciton separation.by Timothy David Heidel.Ph.D
The invisible artist: Arrangers in popular music (1950-2000): Their contribution and techniques
No full textThis thesis was submitted for the degree of Doctor of Philosophy and was awarded by Brunel University.This thesis is based on the research conducted by the author for the series,
Richard Niles' History of Pop Arranging, seven thirty-minute documentary
programmes for BBC Radio 2, researched, written and presented by the author and
broadcast in 2003. It also draws on interviews conducted by the author (and other
research) between 2002 and 2007 both for the radio series and for this thesis and on
the author's experience as a professional arranger in popular music working with
many of the genre's significant recording artists including Paul McCartney, Ray
Charles, Cher, Tina Turner, Westlife, Tears For Fears, Dusty Springfield, James
Brown, Pet Shop Boys, Kylie Minogue and producers including Trevor Hom, Steve
Lipson, Steve Mac and Steve Anderson.
It will be argued that the role of the arranger in popular music has often been
undervalued and that during a critical period of popular music history (1950-2000)
arrangers played a significant part in the evolution of musical content. This thesis is,
to the best of the author's knowledge, the first time (apart from the above mentioned
documentary) the subject has ever been examined. The arranger is "invisible" because musical arrangers are often un-credited on
record liner notes or in books or articles concerning popular music. A considerable
amount of research has been necessary to determine who wrote many of the
arrangements considered herein. Motown's Berry Gordy purposely kept the names of
musicians and arrangers off the records because he feared others might 'poach' the
trademark 'Motown Sound'. Other record labels considered the job of the arranger to
be reminiscent of an earlier era, diluting the Rock 'n' Roll image of emotion and
spontanaeity they wished to promote. Some producers and recording artists disliked
sharing credit for their work. Motown arranger David Van dePitte told the author that
arranging was "thankless and anonymous - a very service-oriented profession where
others often take credit for what you've done." Arranging has therefore remained an
intrinsically unseen art created by 'invisible' artists. By analyzing many recordings,
revealing the techniques and concepts they have used in their work to create popular
records, arrangers and their art will be made more 'visible'
The implementation dynamics of continuous improvement throughout the corporate hierarchy based on lean six sigma at DTE energy by Timothy David Quinn.
No full textThesis (Ph. D.)--Massachusetts Institute of Technology, Sloan School of Management, 2011.This electronic version was submitted by the student author. The certified thesis is available in the Institute Archives and Special Collections.Cataloged from student submitted PDF version of thesis.Includes bibliographical references (p. 409-412).This dissertation comprises a case study and formal simulation model of DTE Energy's Lean Six Sigma continuous-improvement (CI) program from its inception in 1998 through the end of 2009. The case history is based on qualitative fieldwork involving interviews, direct observation, and collection of company documents and records. DTE Energy is one of the top 20 largest electricity and natural gas utilities in the U.S. It adopted CI from its automotive industrial customers in southeast Michigan. During the 12-year period I studied, DTE Energy's CI initiative was stressed by three organizational crises. Typical of other companies' CI initiatives, DTE Energy's success with CI was variable, prompting experiments and revisions to its CI training and methods, to its tactics for garnering managers' attention and support, and to its methods for orchestrating improvement work. Several leaders of the CI initiative were graduates of MIT's Leaders for Manufacturing program and were heavily influenced by research on the Toyota Production System (TPS) by Steven Spear (e.g., Spear and Bowen 1999) and Jeffrey Liker (e.g., Liker 2004). About halfway through this history, DTE Energy added Six Sigma tools and practices to its CI initiative, creating a Lean Six Sigma program. I formulated a System Dynamics (SD) simulation model based on this case study. In this dissertation, I elaborate and extend previous work in the SD literature on the implementation dynamics of CI initiatives, especially Sterman and colleagues' (1997) model of the Total Quality Management (TQM) program at Analog Devices. My model represents explicitly the corporate hierarchy, which I divided into three levels: senior executives, middle managers, and front-line employees. I also examined the interactions between front-line employees engaging in their own Lean-style CI activities and Six Sigma Black Belts doing CI projects. Based on my simulation analysis, I find that managers' and Black Belts' support and coaching required by front-line employees is usually chronically inadequate. I also find that Black Belts or industrial engineers, as full-time experts for process redesign and improvement, are crucial to the growth and long-term sustainability of a company's CI initiative.Ph.D
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