7,032 research outputs found
Mitochondrial genetics of yeast / by David F. Callen
No full textv, 100 leaves : ill., graphs, tables ; 30 cm.Thesis (Ph.D.) -- University of Adelaide, Dept. of Genetics, 197
Azobenzene-containing photoswitchable proteasome inhibitors with selective activity and cellular toxicity
No full textAccepted 8 June 2017Abstract not availableBeatriz Blanco, Kathryn A. Palasis, Alaknanda Adwal, David F. Callen, Andrew D. Abel
Absence of the Epstein-Barr virus genome in breast cancer-derived cell lines
No full text© 2003 Oxford University PressPeter Speck, David F. Callen, Richard Longnecke
Assignment of the Human CC Chemokine Gene TARC (SCYA17) to chromosome 16q13
No full textNomiyama, Hisayuki ; Imai, Toshio ; Kusuda, Jun ; Miura, Retsu ; Callen, David F. ; Yoshie, Osam
sj-docx-1-jad-10.1177_10870547231155875 – Supplemental material for Progress and Pitfalls in the Provision of Quality Care for Adults With Attention Deficit Hyperactivity Disorder in Primary Care
No full textSupplemental material, sj-docx-1-jad-10.1177_10870547231155875 for Progress and Pitfalls in the Provision of Quality Care for Adults With Attention Deficit Hyperactivity Disorder in Primary Care by Elisabeth F. Callen, Tarin L. Clay, Jillian Alai, David W. Goodman, Lenard A. Adler, Joel Shields and Stephen V. Faraone in Journal of Attention Disorders</p
sj-docx-1-jad-10.1177_10870547231218449 – Supplemental material for Measuring Quality Care for Adult ADHD Patients: How Much Does Gender and Gender Identity Matter?
No full textSupplemental material, sj-docx-1-jad-10.1177_10870547231218449 for Measuring Quality Care for Adult ADHD Patients: How Much Does Gender and Gender Identity Matter? by Tarin Clay, Elisabeth F. Callen, Jill Alai, David W. Goodman, Lenard A. Adler and Stephen V. Faraone in Journal of Attention Disorders</p
Ankrd11 is a chromatin regulator involved in autism that is essential for neural development
No full textAbstract not availableDenis Gallagher, Anastassia Voronova, Mark A. Zander, Gonzalo I. Cancino, Alexa Bramall, Matthew P. Krause, Clemer Abad, Mustafa Tekin, Paul M. Neilsen, David F. Callen, Stephen W. Scherer, Gordon M. Keller, David R. Kaplan, Katherina Walz, and Freda D. Mille
Landsat MSS classification of fire fuel types in Wood Buffalo National Park, northern Canada
No full textJ1: Global Ecology & Biogeography Letters; M3: Article; Milne, David Franklin, Steven E. Wilson, Bradley A. Ghitter, Geoff Heathcott, Mark McCaffrey, Thomas M. Ow, Charlotte F. Y.; Source Information: Mar1994, Vol. 4 Issue 2, p33; Subject Term: FOREST fires; Author-Supplied Keyword: Canada (Wood Buffalo National Park); Author-Supplied Keyword: Forest fire; Author-Supplied Keyword: Fuel type classification; Author-Supplied Keyword: Landsat data; Number of Pages: 0p; Document Type: Articl
A template-based approach to inhibitors of calpain 2, 20S proteasome, and HIV-1 protease
No full textArticle first published online: 15 OCT 2013Specificity counts: A template-based approach to protease inhibitors is presented using a core macrocycle that presents a generic β-strand template for binding to protease active sites. This is then specifically functionalized at P2 , and the C and N termini to give inhibitors of calpain 2, 20S proteasome, and HIV-1 protease.Seth A. Jones, Paul M. Neilsen, Limei Siew, David F. Callen, Nathan E. Goldfarb, Ben M. Dunn, and Andrew D. Abel
Targeting the p53 pathway in Ewing Sarcoma
No full textExtent: 17p.The p53 tumour suppressor plays a pivotal role in the prevention of oncogenic transformation. Cancers frequently evade the potent antitumour surveillance mechanisms of p53 through mutation of the TP53 gene, with approximately 50% of all human malignancies expressing dysfunctional, mutated p53 proteins. Interestingly, genetic lesions in the TP53 gene are only observed in 10% of Ewing Sarcomas, with the majority of these sarcomas expressing a functional wild-type p53. In addition, the p53 downstream signaling pathways and DNA-damage cell cycle checkpoints remain functionally intact in these sarcomas. This paper summarizes recent insights into the functional capabilities and regulation of p53 in Ewing Sarcoma, with a particular focus on the cross-talk between p53 and the EWS-FLI1 gene rearrangement frequently associated with this disease. The development of several activators of p53 is discussed, with recent evidence demonstrating the potential of small molecule p53 activators as a promising systemic therapeutic approach for the treatment of Ewing Sarcomas with wild-type p53.Paul M. Neilsen, Kathleen I. Pishas, David F. Callen and David M. Thoma
- …
