49,577 research outputs found
Quadrature Rules in the Isogeometric Galerkin Method: State of the Art and an Introduction to Weighted Quadrature
No full textIn this paper we introduce the quadrature needed in the IsoGeometric
Galekin method. Quadrature rules affect the cost of the assembly of the discrete
counterpart of the IgA method, so that the search for efficient quadrature is an active
research topic. The focus of the first part is on a brief survey on the contributions
available for the reduction of computational costs for such issue. We review the
Generalized gaussian strategies and the reduced quadrature introduced. Then we
present the novelty of weighted quadrature, recently proposed by Calabro, Sangalli `
and Tani for the efficient assembly. We detail the construction of such rules and
give some examples. Finally we end with some remark on current work and further
developments
First nitrogen-seeding experiments in JET with the ITER-like Wall
No full textIn this contribution we present results from the first N2 seeding experiments in JET performed after installation of the ITER-like Wall. Gas balance measurements for seeded L-mode discharges indicate very strong N2 retention as well as a potential increase in D2 retention. The possible influence of ammonia production on this apparent retention is discussed. Plasma parameters and impurity content were monitored throughout the seeded discharges as well as during subsequent clean-up discharges. These experiments give first insight into phenomena related to the use of nitrogen as seeding gas in JET with the ITER-like Wall, such as ammonia production and nitrogen legacy. © 2013 Elsevier B.V. All rights reserved
Feasibility and usefulness of right ventricular ultrasonic tissue characterization with integrated backscatter in patients with unsuccessfully operatively "repaired" tetralogy of Fallot
No full text“Messina 1908-2008”: Progetto di ricerca integrato per l’area Calabro - Peloritana. L’esperimento di sismica passiva
No full textIl 28 dicembre 1908 un forte terremoto colpì duramente le città di Messina e di Regg io Calabria e molteplici
centri abitati limitrofi. L’evento sismico di Mw=7.1 generò un maremoto e causò circa 100.000 morti. Durante
il 2008 numerose sono state le iniziative per rievocare tale importante terremoto che è ricordato nella storia
come il più forte avvenuto in Italia. Tra le iniziative promosse dall’Istituto Nazionale di Geofisica e Vulcanologia vi
è il progetto di ricerca “Messina 1908-2008” le cui finalità sono far convergere i dati sismici e geodetici g ià a
disposizione dei singoli gruppi di ricerca in un’unica banca dati e nel contempo promuoverne l’acquisizione di nuovi.
In questo rapporto è descritto l’esperimento di sismica passiva integrato mare-terra iniziato ad ottobre 2007 e
ter minato nel gennaio 2010 avente l’obiettivo di acquisire nuovi dati di alta qualità e dettaglio per ottenere una
migliore definizione della microsismicità locale. Ciò consentirà di raggiungere una migliore comprensione di come
inter ag iscano il processo di subduzione e le dinamiche superficiali nell’area dell’arco Calabro Peloritano ed in
particolare nello stretto di Messina.Istituto Nazionale di Geofisica e VulcanologiaPublished1.1. TTC - Monitoraggio sismico del territorio nazionaleope
New horizons from immunotherapy in malignant pleural mesothelioma
No full textMalignant pleural mesothelioma (MPM) is an aggressive disease with a severe prognosis. Medical treatment for MPM unresectable patients is still unsatisfactory; therefore novel therapeutic approaches are urgently needed. Immunotherapy represents a promising treatment for MPM patients. Here, we'll discuss the most promising immunotherapeutic treatments currently under active investigation for this still dreadful disease
Prognostic value of intra-left ventricular electromechanical asynchrony in patients with hypertrophic cardiomyopathy
No full textStapled transanal rectal resection in solitary rectal ulcer associated with prolapse of the rectum: a prospective study
No full textPURPOSE : At present, none of the conventional surgical treatments of solitary rectal ulcer associated with internal rectal prolapse seems to be satisfactory because of the high incidence of recurrence. The stapled transanal rectal resection has been demostrated to successfully cure patients with internal rectal prolapse associated with rectocele, or prolapsed hemorrhoids. This prospective study was designed to evluate the short-term and long-term results of stapled transanal rectal resection in patients affected by solitary rectal ulcer associated with internal rectal prolapse and nonresponders to biofeedback therapy.
METHODS: Fourteen patients were selected on the basis of validated constipation and continence scorings, clinical examination, anorectal manometry, defecography, and colonoscopy and were submitted to biofeedback therapy. Ten nonresponders were operated on and followed up with incidence of failure, defined as no improvement of synptoms and/or recurrence of rectal ulceration, as the primary outcome measure. Operative time, hospital stay, postoperative pain, time to return to normal activity, overall patient satisfaction index, and presence of residual rectal prolapse also were evaluated.
RESULTS: At a mean follow-up of 27.2 (range, 24-34)months symptoms significantly improved, with 80 percent of excellent/good results and none of the ten operated patients showed a recurrence of rectal ulcer. Operative time, hospital stay, and time to return to normal activity were similar to those reported after stapled transanal rectal resection for obstructed defecation, whereas postoperative pain was slightly higher. One patient complained of perineal abscess,requiring surgery.
DISCUSSION: The stapled transanal rectal resection is safe and effective in the cure of solitary rectal ulcer associated with internal rectal prolapse, with minimal complications and no recurrences after two years. Randomized trials with sufficient number of patients are necessary to compare the efficacy of stapled transanal rectal resection with the traditional surgical treatments of this rare condition
Inflammation: The Link Between Obesity and Cardiovascular Risk
No full textIt is now clear that adipose tissue is more than just an area for fat storage, as suggested by a large body of recent literature. Fat, in particular abdominal depots, is an active source of biological mediators, which affect metabolic pathways and vascular function. These effects seem to be in part related to inflammation, especially in the pathogenesis and progression of atherosclerosis. As cardiovascular pathology, in particular coronary artery disease, still represents one of the main causes of morbidity and mortality in Western countries, the need for markers to make a correct risk stratification of patients is rising with the increasing complexity of treatment strategies now available. Thus, molecules produced by adipose tissue, known as adipocytokines, have been studied largely for their potential use as biomarkers both in primary and secondary prevention. The aim of this article is to examine recent evidence about the main adipocytokines, including leptin, adiponectin, resistin, and C-reactive protein, of which adipose tissue an important source. © 2010 Springer Science+Business Media, LLC
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