31,111 research outputs found
Getting Started as a Medical Teacher in Times of Change
No full textMedical school teaching is a skill that is very often learned on the job. The faculty comprised of researchers and clinicians are expert in many biomedical disciplines, but familiarity with learning theories and pedagogy are usually not included in their knowledge and skill sets. The pressure to see patients and acquire extramural funding leaves little time for faculty to learn how to teach. When coupled with the natural attrition of senior faculty it is necessary to start junior faculty on the correct path to being effective medical educators who are capable of lecturing and facilitating. Institutions cannot afford to have medical educators learn through trial and error. The standards set by the Liaison Committee on Medical Education (LCME) are also creating an urgency to produce competent teachers as quickly as possible. Novice teachers need to be able to use these standards to align their teaching with goals, objectives and the appropriate pedagogy. This article is designed to be a self-directed guide describing some essentials that a newly hired faculty member can quickly use to get started. An institutional faculty development program can then serve to build upon and enrich the experience for the new faculty member.This is the authors' accepted manuscript of the article. The final publication is available at Springer via http://dx.doi.org/doi:10.1007/s40670-014-0098-y.Peer reviewe
18F-DOPA PET/CT and MRI findings in a patient with multiple meningiomas
No full textA 56-year-old man was referred to our Department for a 2-year story of upper limb tremor, severe headache, and episodes of confusion. Brain F-DOPA PET/CT showed multiple areas of tracer uptake in the two hemispheres of the brain. Subsequent MRI displayed demyelinating foci with high contrast enhancement. Histological specimen confirmed the diagnosis of multiple meningiomas
[Palestra pharmaceutica, chimico-galenica
No full text[15], 480, [24]p., [4]h. de láms. grab. : il.Contiene: "Explicación de las láminas, en donde se hallan los hornos, vasos, y varios instrumentos chimico-pharmaceuticos, necessarios para las operaciones", "Tabla de los capítulos contenidos en esta obra", "Explicación de los más comunes caracteres chimicos" e "Indice de las cosas más memorables contenidas en esta obra".Título de partida. Título y mención de responsabilidad tomados del cuerpo de la obra.Las [4] h. de láminas grab.: "P, Calabria, F.", representan instrumental químico y la última es un retrato del autor.Incluye: Notas al margen del texto
Sous-facteurs de L(F∞) d'indice 4cos2π/n,n≥3
No full textLet Q be a factor of type II1, λ a number in the Jones discrete series {4cosπ/m:m≥3}, and {ei} the Jones projections associated with λ. Denote by A2n and A1n the finite-dimensional von Neumann algebras generated, respectively, by {1,e2,⋯,en} and {1,e1,⋯,en}, with the corresponding traces. The author shows that, for n sufficiently large, the index of the inclusion An=(Q⊗A2n)∗A2nA1n⊂(Q⊗A2n+1)∗A2n+1A1n+1=An+1 is equal to λ (here ∗ denotes the reduced, amalgamated free product of the algebras in question). Using the random matrix model of Voiculescu, he proves that if Q is the von Neumann algebra L(F∞) of the free group with infinitely many generators, then An is isomorphic to L(F∞).
The two facts together imply the existence, for any λ in the Jones discrete series, of an irreducible subfactor of L(F∞) of index λ. This constitutes the first example of a nonhyperfinite, non-Γ II1 factor such that its Jones invariant is fully computable (the existence of nonirreducible subfactors of L(F∞) for any index ≥4 is a simple consequence of known results)
Decay assessment of stone-built cultural heritage: The case study of the cosenza cathedral façade (south calabria, italy)
No full textThis study aims to assess the different decay phenomena affecting the Cosenza Cathedral façade (Calabria, South Italy) through the evaluation of the relative damage indices. For this goal, a multidisciplinary approach was applied exploiting both nondestructive and microdestructive techniques. Such a combination enabled proposing an intervention priority scale that can be helpful to institutions when planning a prompt restoration intervention. The results suggest the efficiency of this approach to obtain a multidisciplinary diagnostic and conservation system for the management and valorization of the Cultural Heritage also in terms of monitoring, maintenance, and selection of the most suitable restoration procedures over time
Contaminanti Emergenti nelle acque: il caso dei Fluorochinoloni
No full textLa presenza di residui di farmaci per uso umano ed animale nelle acque reflue è un problema di cui solo recentemente si sta prendendo consapevolezza. Queste sostanze, dopo aver esaurito la loro funzione all'interno del corpo umano e/o animale, sono escreti e veicolati dalle acque fognarie. Gli impianti di depurazione tradizionali non sono in grado di abbatterle totalmente perché progettati per altri scopi. In base alle loro caratteristiche chimico-fisiche, molti di questi composti metabolizzati persistono nelle acque effluenti dagli impianti di depurazione e raggiungono le acque superficiali ove si accumulano; altri rimangono inglobati nei fanghi che spesso sono utilizzati come ammendanti in agricoltura. Il trasferimento successivo di lisciviazione nelle falde acquifere è un processo piuttosto ovvio. I "pharmaceuticals", sono considerati micro inquinanti emergenti e purtroppo non hanno uno status normativo..
A supporto della rimozione microbiologica, dimostratasi non efficace, tecniche di ossidazione avanzate (AOPs) consentono spesso la completa mineralizzazione delle molecole madri e dei metaboliti eventualmente formatisi durante il loro percorso di vita.
Questo studio ha focalizzato l'attenzione sui fluorochinoloni, farmaci ad ampio spettro antibatterico somministrati per combattere infezioni delle basse vie urinarie e intestinali.
Prove di fotolisi e di fotocatalisi in acqua ultrapura e di falda, adoperando biossido di Titanio, H2O2 e perossidasi di rafano, sono state condotte utilizzando molecole pure e formulati commerciali di Levofloxacin, Moxifloxacin e Norfloxacin.
Le prove d’irradiazione diretta hanno evidenziato che le molecole madri dei prodotti commerciali sono fotodegradate in poche ore mentre i metaboliti sono più persistenti e richiedono tempi di trattamento notevolmente più lunghi. Al buio le molecole sono stabili, a conferma di quanto riportato da alcuni ricercatori (1, 2).
Anche se la European Medicines Agency (EMEA) riconosce che non è possibile applicare un limite ambientale per i residui di farmaci “molto specifici e molto attivi”, i risultati ottenuti in questo lavoro supportano la motivazione di includere i composti farmaceutici nel monitoraggio della qualità delle acque reflue e degli effluenti degli impianti di trattamento nonché la necessità di affiancare sistemi più energici di degradazione alle tecniche di depurazione tradizionali
Multidisciplinary approach to characterize archaeological materials and status of conservation of the Roman thermae of reggio Calabria Site (Calabria, South Italy)
No full textThis multidisciplinary research focuses on diagnostic investigations to characterize the archaeological materials, as well as the alteration and degradation forms detected at the Roman Thermae of Reggio Calabria (Calabria, South Italy) site. The thermal complex, (dating I-II century B.C.), was built around three main rooms such as the caldarium (hot bath), the tepidarium (warm bath) and the frigidarium (cold bath), all connected to a central room through several entrances. The central hall still preserves a suggestive mosaic floor dating between the II and III century A.D., characterized by geometric motifs and black and white tesserae. Fragments of various archaeological stone materials, such as bricks, mortars, sedimentary, volcanic and metamorphic rocks have been studied with different and complementary techniques. Particularly, polarized optical microscopy (POM) and X-ray diffractometry (XRD) were performed to characterize the materials employed to construct the site and evaluate their state of preservation. Finally, laboratory microbiological culture analysis was conducted to identify the main microorganisms composing the biological patinas detected on the sampled materials. Results allowed us to evaluate the most suitable restoration procedures to conduct at the archaeological site, considering the different stone materials present in the studied area and their state of conservation
Molecular characterization of wine grape cultivars from Calabria
No full textThe wine sector is one of the most active and profitable in Italy; Italy is the largest wine producer in the world, followed by Spain and France. For this reason, it is subject to extensive legislative discipline. Calabria ranks sixteenth among Italian regions for wine production; however, in recent years, much effort has been made to promote the wine sector in this region. Nine Calabrian wines are designated as PDO (protected designation of origin) and ten wines as PGI (protected geographical indication). Among the PDO wines, Terre di Cosenza and Cirò are the most famous. Fraud prevention is necessary for consumer protection and for product valorization and promotion. Microsatellite marker analysis represents a reliable and effective tool for varietal characterization, allowing the detection of adulteration in the winemaking process. We sampled 20 grapevine cultivars from different areas of Calabria commonly used for production of the PDO wine Terre di Cosenza and 20 cultivars from other Italian regions in order to carry out a molecular characterization. The analysis was performed through six simple sequence repeat (SSR) markers proposed by the International Organization of Vine and Wine (OIV), VVSS2, VVMD5, VVMD7, VVMD27, VrZAG62, and VrZAG79. Some of the cultivars showed the same molecular profile, revealing the presence of synonymies and incorrect name assignment
The Miocene deposits of the Cirò Basin in the evolution of the peri-Ionian region, eastern Calabria
No full textThe Cirò Basin is located in the north-eastern partion of Calabria, between the Ionian Sea and the Sila slopes. In this area, basin successions of the Neogene and Quaternary age overlap the Paleozoic metamorphic basement of the Sila Unit. In particular, there are units consisting of continental clastic facies and coastal facies that are the basis of the Tortonian-Messinian transgression. An accurate geological-structural survey, combined with sedimentological and stratigraphic analysis, has allowed to define the limits of the Cirò Basin and the stratigraphic relationships between the various outcropping Miocene deposits. Five distinct litofacies have been recognized, each of which contains both lateral and vertical variations.The main tectonic structures control the architecture and evolution of main Neogene basins of the Calabrian terranes. From the Neogene to the Quaternary, the history of orogenic building was mainly controlled by the activity of NW-SE oriented faults and shear zones characterised by left-trascurrent kinematics. Deformation is well evidenced in the tectono-sedimentary evolution of the wedge-top basins as well as in the retro-arc domain
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