207,471 research outputs found
Response to Nagai et al.
No full textRefers to: Nagai M, Dote K, Kato M, Sasaki S, Oda N. The insular cortex and QTc interval: Was there the effect of hemispheric lateralization? Eur J Neurol 2017; 24: e45. - Referred to: Turri G, Calabrese M, Pancheri E, Monaco S, Gajofatto A, Marafioti V. QTc interval in patients with multiple sclerosis: an infer- ence from the insula of Reil? Eur J Neurol 2017; 24: 491 – 496
Five-loop epsilon expansion for U(n) x U(m) models: finite-temperature phase transition in light QCD
No full textWe consider the U(n) x U(m) symmetric Phi(4) lagrangian to describe the finite-temperature phase transition in QCD in the limit of vanishing quark masses with n=M=N(f) flavors and unbroken anomaly at T(c). We compute the Renormalization Group functions to five-loop order in Minimal Subtraction scheme. Such higher order functions allow to describe accurately the three-dimensional fixed-point structure in the plane (n, m), and to reconstruct the line n(+) (m, d) which limits the region of second-order phase transitions by an expansion in epsilon=4-d. We always find n(+) (m, 3)>m, thus no three-dimensional stable fixed point exists for n=m and the finite temperature transition in light QCD should be first-order. This result is confirmed by the pseudo-epsilon analysis of massive six-loop three dimensional series
Self-descriptive IF THEN rules from signal measurements : a holonic-based computational technique
No full textA holon is a bio-inspired conceptual entity that, like cells in a living organism, behaves as a part and a whole at the
same time. Holonic systems have been the subject of intense research in the latest years due to their properties such as selforganization, self-similarity and capability of handling hierarchically-nested granularity levels. Lesser attention indeed
has been paid by engineers to the aspect of self-description, i. e. the ability to describe itself in terms of self-contained descriptors.
Self-description can be useful in measurement settings where the only available knowledge is embedded in data in terms of hidden rules behind observed signals. In this work, a heuristic technique
is employed to extract self-descriptive IF THEN rules from measurement signals. These rules are considered holonic in that
they represent a whole described in terms of relationships among their parts. An example taken from a real measurement scenario
is reported and commented in detail
Five-loop epsilon expansion for O (n) X O (m) spin models
No full textWe compute the renormalization group functions of a Landau-Ginzburg-Wilson Hamiltonian with O(n) x O(m) symmetry up to five-loop in minimal subtraction scheme. The line n(+)(m, d), which limits the region of second-order phase transition, is reconstructed in the framework of the epsilon = 4 - d expansion for generic values of m up to O(epsilon(5)). For the physically interesting case of noncollinear but planar orderings (m = 2) we obtain n(+)(2, 3) = 6.1(6) by exploiting different resummation procedures. We substantiate this results reanalyzing six-loop fixed dimension series with pseudo-epsilon expansion, obtaining n(+)(2, 3) = 6.22(12). We also provide predictions for the critical exponents characterizing the second-order phase transition occurring for n > n(+). (C) 2003 Elsevier B.V. All rights reserved
Terminologia specialistica per l’artigianato orafo e tessile calabrese
No full textIl presente lavoro illustra obiettivi, metodologia e risultati preliminari di attività di ricerca condotte in due comparti dell’artigianato d’arte tradizionale calabrese e orientate all’estrazione, all’analisi e alla modellizzazione di competenze e conoscenze tacite proprie del saper fare degli esperti di dominio. Oltre che sulla costruzione di una base di conoscenza e di un thesaurus a faccette come strumento di accesso all’informazione in essa contenuta e organizzata, particolare attenzione sarà rivolta anche ad aspetti di carattere terminologico relativi tanto all’analisi delle peculiarità e delle incongruenze rilevate nell’uso dei termini da parte degli esperti, quanto alle funzioni di controllo esercitate dagli strumenti costruiti
Basal and stress-induced modulation of activity-regulated cytoskeletal associated protein (Arc) in the rat brain following duloxetine treatment
No full textTherapeutic efficacy of antidepressant drugs appears to be related to their ability in producing neuroadaptive changes that restore normal brain function. Activity-regulated cytoskeletal associated protein (Arc) is an effector immediate early gene that plays a fundamental role in activity-dependent neural plasticity in corticolimbic brain regions and has been implicated in the modulation of several functions known to be profoundly perturbed in depressive states.
In the present study, we investigated transcriptional and translational changes of Arc in response to acute or chronic treatment with the novel antidepressant duloxetine.
Although a limited increase of Arc messenger RNA (mRNA) levels was found in some structures after acute antidepressant administration, a marked up-regulation of its gene expression was found after chronic treatment, primarily at the level of frontal cortex. The changes observed after prolonged duloxetine administration strongly correlates with those previously reported on brain-derived neurotrophic factor mRNA levels Calabrese et al. (Neuropsychopharmacol 32:2351-2359, 2007). In addition, we found an anatomical-specific influence of chronic duloxetine on stress-dependent Arc modulation, which was limited to the frontal cortex.
We suggest that these neuroadaptive changes, among others, might contribute to the normalization of neuroplastic defects associated with mood disorder
Co-creating value in urban public policy contexts: a different approach
No full textUrban areas face daunting economic challenges that have increased in scope in recent years. At the same time, cities provide for opportunities for growth and value creation. The interplay of these challenges and opportunities represents an area of intervention for policymakers and researchers. However, traditional approaches to urban policy deriving from managerial and economic policy theories present difficulties mainly related to capacities to counterbalance the interests and expectations of a multitude of stakeholders participating in the value co-creation process and to allow different components to synergically contribute to the sustainability of a system. The author proposes an innovative approach to urban public policy that involves adopting the theoretical corpus of the viable systems approach (“VSA”). Urban planning is particularly analyzed as systemic components of urban areas with the aim of investigating decision-making processes that support an integrated, efficient, effective and sustainable management of territories as multidimensional, multisectoral and multi-stakeholder entities. By recovering different settings, the VSA is designed for the co-creation of value as the capacity for viable systems to increase their chances of survival in their own contexts. Value derives first from strategic decisions made to find both dyadic and context consonance. Through its strategic decisions, the governing body of the territory develops a specific system as an overall synthesis of all possible systems organized within a specific area, identifying patterns of development agreed upon by the several stakeholders of the given territory. In the dynamics of value co-creation in systemic multi-subjective organizations where levels of complexity are particularly high, research on consonance among different stakeholders is particularly important to achieve the most value for a territory. In this respect, the VSA may constitute a valid tool for finding necessary capacities to imagine evolutionary paths toward new competencies
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