1,721,182 research outputs found
Non-IgE/Mixed Food Allergies and Functional Gastrointestinal Disorder: A Common Thread between Childhood and Adulthood
No full textAdverse food reactions (AFRs) are abnormal clinical responses related to food or the ingestion of a food component, including drinks, food additives, and dietary supplements [...
Periscopio sulla celiachia. Quali esami principali per diagnosticare la malattia: l’importanza dei test genetici e basati sugli anticorpi
No full textN/
Coeliac disease: changing diagnostic criteria?
No full textCoeliac disease (CD) is a chronic,
multisystemic, autoimmune disorder, induced by
gluten exposure, in genetically sensitive
individuals (1-3). Its clinical presentation is
extremely various, and changes considerably from
full-blown malabsorption syndrome, seen in the
classic childhood-onset disease, to subtle and
atypical symptomatology, especially in the lateonset
forms. The prevalence of CD varies widely
in different parts of the world; however recent
studies, employing new highly sensitive and
specific serologic assays, have shown it to be a
fairly common disease worldwide, about 1% in
general population. This variability is most
probably due to the differences in the diagnostic
protocols used, the level of public health
awareness, the nutrition habits (large use of gluten
free cereals – i.e. rice, corn) and also, partially, to
the true differences in the incidence of the disease
(4)
Clinical and immunological features of celiac disease in patients with Type 1 diabetes mellitus
No full textCeliac disease (CD) is one of the most frequent autoimmune disorders occurring in Type 1 diabetes mellitus (T1DM). The prevalence of CD in T1DM varies from 3 to 16%, with a mean prevalence of 8%. The clinical presentation of CD in T1DM is classified as symptomless in approximately half of cases, but a more accurate analysis often discloses a wide array of symptoms suggestive of CD. Both T1DM and CD show the same genetic background and an abnormal small intestinal immune response with inflammation and a variable grade of enteropathy. Serological screening for CD should be performed in all T1DM patients by means of antibodies to tissue transglutaminase at T1DM onset. T1DM patients found to be celiacs must be treated by a gluten-free diet. Potential CD cases (especially when asymptomatic) should be kept on a gluten-containing diet with a careful clinical and antibody follow-up, since many of them will not develop villous atrophy
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Is Autoimmunity More Predominant in Nonceliac Wheat Sensitivity Than Celiac Disease?
No full textThe recent paper published by Carroccio et al reported on the prevalence of autoimmunity (as identified by positivity of antinuclear antibodies [ANA] and associated autoimmune disorders) in nonceliac wheat sensitivity (NCWS) versus celiac disease (CD) and irritable bowel syndrome (IBS). More in detail, the results of the study, based on a retrospective and prospective arm, showed that the prevalence of ANA in NCWS was significantly higher than in CD and IBS (46% in NCWS vs 24% in CD and 2% in IBS, retrospectively; and 28% in NCWS vs 7.5% in CD and 6% in IBS, prospectively). Moreover, in both retrospective and prospective analysis, autoimmune disorders (mainly autoimmune thyroiditis) were found in a slightly higher proportion in NCWS (29% vs 24%) than CD (21% vs 20%). Both NCWS and CD showed a significantly higher prevalence of autoimmune disorders than IBS. ANA were significantly related to HLA-DQ2 and -DQ8 in NCWS (both retrospectively and prospectively), whereas these autoantibodies were associated significantly with autoimmune disorders only in the prospective arm
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
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