1,720,992 research outputs found
Treatment of N-alkyl-N'-tosylhydrazines with oxidizing agents: a new route to alkanesulphinic esters
No full text
Generalization possibilities of autocatalytic absolute enantioselective synthesis
No full textA simple empirical formula enables the quantitative description of chiral autocatalysis. This formula was used for the prediction of the number of consecutive autocatalytic reaction cycles needed to obtain a high enantiomeric excess without chiral auxiliary or an asymmetric physical field (absolute enantioselective synthesis). The results show, that even less selective Soai-type systems can be used for absolute enantioselective synthesis, which, therefore, appears to be a fairly general phenomenon. (c) 2006 Published by Elsevier Ltd
THE PALLADIUM-CATALYZED AMINATION OF ALLYLIC CARBONATES WITH DI-TERT-BUTYL IMINODICARBONATE UNDER NEUTRAL CONDITIONS
No full textN,N-Di-tert-butoxycarbonylallylamines are prepared through a palladium-catalyzed reaction of allylic carbonates with di-tert-butyliminodicarbonate under neutral conditions. Allylic carbonates producing monosobstituted pi-allylpalladium complexes tend to give preferentially diprotected allylic amines with the nitrogen bonded to the less substituted carbon atom in good yields. The reaction rate is relatively fast. With allylic carbonates producing disubstituted pi-allylpalladium complexes, the reaction rate is lower as are the yields. The method is particularly suited for chemoselective amination and sequential amination-alkylation reactions
- …
