43 research outputs found
MENTAL HEALTH SUPPORT PROGRAM FOR HEALTHCARE PROFESSIONALS IN A PANDEMIC HOSPITAL IN TURKEY AND ITS RESULTS ON ANXIETY, DEPRESSION, INSOMNIA AND SEXUAL DISORDERS
No full textBackground: The COVID-19 pandemic has put enormous stress on the health care workers, threatening not only their physical
health but also their mental well-being. No mental health support program (MHSP) addressing depression and anxiety in healthcare
workers (HCWs), has been shown to be effective in Turkey previously. We aimed to measure the effect of our MHSP among
healthcare workers who applied for psychological help associated with the COVID-19 pandemic.
Subjects and methods: An MHSP has been created for healthcare professionals working in a pandemic hospital during the
COVID-19 period. Health workers were recruited between July and September 2020. Anxiety, depression, and insomnia levels were
evaluated with HAM-A (Hamilton Anxiety Scale), HDRS (Hamilton Depression Scale), and Insomnia Severity Index (ISI) before and
after the intervention. Sexual complaints were questioned by a consultant psychiatrist. MHSP (n=31), and treatment as usual (TAU,
n=27) groups were compared using repeated-measures ANOVA.
Results: Sociodemographic data, medical history of COVID-19, and psychiatric diagnoses were similar between the groups.
There was no difference in baseline HAM-A, HDRS, and ISI scores (p>0.05). At the end of the study, there was a significant difference
between study groups regarding anxiety scores (For post-treatment, MHSP=8.0±2.6 vs. TAU=17.9±3.1,
A case of immune-mediated type 1 diabetes mellitus due to congenital rubella infection
No full textCongenital rubella infection is a transplacental infection that can cause intrauterine growth retardation, cataracts, patent ductus arteriosus, hearing loss, microcephaly, thrombocytopenia, and severe fetal injury. It has been shown that type 1 diabetes mellitus develops in 12%-20% of patients with congenital rubella infection, and disorders in the oral glucose tolerance test is observed in 40% of patients. No biochemical or serological markers exist which could indicate that type 1 diabetes was caused by a congenital rubella infection. We report a 13-year-old male patient who was admitted to our hospital with complaints of new-onset polyuria, polydipsia, urination, and weight loss. In addition, he was found to have neurosensory hearing loss, patent ductus arteriosus, and microcephaly. Immune-mediated type 1 diabetes mellitus was considered due to the fact that the autoantibodies of diabetes mellitus were positive
Is There a Relationship Between Immune-Mediated Type 1 Diabetes Mellitus and Congenital Rubella Infection?
No full textParametric Analysis of Viscoelastic Hyperboloidal Helical Rod
No full textErmis, Merve/0000-0003-0201-6586; Kutlu, Akif/0000-0001-6865-3022; Eratlı, Nihal/0000-0003-3788-9870; OMURTAG, Mehmet Hakki/0000-0003-2669-6459The objective of this study is to perform a pioneering research about a viscoelastic hyperboloidal helical rod having a standard type of distortional behavior and a Kelvin type of bulk compressibility. Field equations are based on the Timoshenko beam theory, and the exact curvatures of the hyperboloidal geometry are considered through the formulation. The numerical analysis is carried out by the mixed finite element method, considering the rotary inertia, in the Laplace space, and the results are transformed back to time space numerically using the modified Durbin's algorithm. A cantilevered hyperboloidal helical rod having solid circular, hollow circular, and thin-walled hollow circular cross sections is handled, and the rod is loaded by rectangular and triangular impulsive types of point load at the tip. Through the analysis, different values of retardation time, three different relaxation functions associated with shear modulus, and three different creep functions associated with bulk modulus are handled. Finally, a benchmark example is presented, and the influence of the loading and the material parameters on the helix geometry is discussed.Scientific and Technological Research Council of Turkey [111M308]; Research Foundation of ITU [38078]The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: This research is supported by the Scientific and Technological Research Council of Turkey under project no. 111M308 and Research Foundation of ITU under project no. 38078
Multi-agent Planning and Coordination for Automated Aircraft Ground Handling
No full textInspired by the vision of fully autonomous airside operations at Schiphol airport, this study aims to contribute to the short-term goal of automated aircraft ground handling. In this research, we design and evaluate a multi-agent system for planning of automated ground handling. There are two main components in the system, task allocation optimization, and multi-agent path planning. To allocate tasks to ground support equipment (GSE) vehicles, an auction mechanism inspired by temporal sequential single item (TeSSI) auction is proposed. Ground handling tasks scheduling for GSE vehicles is modeled as several single-vehicle pickup and delivery optimization problems (SPDP), and the values of the objective functions are applied to generate bids for GSE vehicle agents in the auction. Moreover, Prioritized Safe Interval Path Planning for large agents (LA-SIPP) is used to plan collision-free paths for GSE vehicle agents in the model to execute tasks. Experimental studies have shown that the system is able to perform task allocation and path planning of ground handling tasks for flights in 3 aircraft stands within a 4-hour time in a reasonable computational time. Moreover, the model is capable to replan the tasks for agents when disruption happens. Applying the lowest possible numbers of vehicles used in the current operation, the model can always reach success allocation and path planning rates higher than 81% and 98%, respectively.Aerospace Engineerin
Multi-agent planning and coordination for automated aircraft ground handling
No full textInspired by the vision of fully autonomous airside operations at Schiphol airport, this study aims to contribute to the short-term goal of automated aircraft ground handling. In this research, we design and evaluate a multi-agent system for planning of automated ground handling. There are two main components in the system: task allocation optimization and multi-agent path planning. To allocate tasks to ground support equipment (GSE) vehicles, an auction mechanism inspired by temporal sequential single item (TeSSI) auction is proposed. Ground handling tasks scheduling for GSE vehicles is modeled as several single-vehicle pickup and delivery optimization problems (SPDP), and the values of the objective functions are used to generate bids for GSE vehicle agents in the auction. Prioritized safe interval path planning for large agents (LA-SIPP) is used to plan collision-free paths for GSE vehicle agents in the model to execute tasks. The aim is to increase the success rates of allocating tasks and finding collision free paths without causing flight delays, given the limited resources such as a small number of available GSE vehicles, time windows constraints and conflicting interests of different agents. Due to the results, even for the instances with frequent flights and the most limited resources, the success rates of allocation and path planning were higher than 81% and 98%, respectively. Furthermore, periodic task allocation and path planning of the ground handling tasks for flights in three aircraft stands during a planning time window of the day, as well as replanning in case of disruptions were performed in a short CPU time. There is a lack of research dealing with the complete process of ground handling, since existing studies concerning the automation of ground handling operations involve fleet assignment or task scheduling models without an integration of detailed path planning. Our main contribution is to present a framework that combines task allocation and path planning for automation of ground handling operations and provides solutions using a multi-agent perspective.Air Transport & Operation
COGNITIVE FUNCTIONING AND DIAGNOSTIC ACCURACY OF THE TURKISH VERSION OF THE COLUMBIA-SUICIDE SEVERITY RATING SCALE IN ADOLESCENT SUICIDE ATTEMPTERS
No full textInvestigating Predictors of Clozapine Response in Adolescents with Schizophrenia and Schizoaffective Disorder
No full textObjectives: We aimed to determine the clinical predictors of clozapine response in patients with early-onset schizophrenia (EOS)/schizoaffective disorder and the effect of substance use disorder (SUD) on treatment outcomes. Methods: Medical records of patients with treatment-resistant EOS receiving clozapine were identified for data analysis dated between January 2015 and April 2020. Patients on clozapine were followed in an inpatient unit of a tertiary care mental health hospital. Using the Positive and Negative Symptom Scale (PANSS), >= 30% reduction was defined as the response criteria after clozapine treatment. Results: Of 50 subjects (age: 16.3 +/- 1.3 years, 36.0% female), 22 subjects (44.0%) met the defined response criteria. Clozapine responder (CLZ-R) and clozapine nonresponder (CLZ-NR) groups were similar regarding age at illness onset, sex, and duration of untreated psychosis. The CLZ-R group had higher baseline positive PANSS scores (24.8 +/- 8.1 vs. 17.1 +/- 6.6, p = 0.001, d = 1.0) and total PANSS scores (94.8 +/- 17.2 vs. 80.1 +/- 19.8, p = 0.008, d = 0.8) compared with the CLZ-NR counterparts. The duration of hospital stay was longer in the CLZ-NR group (122.3 +/- 48.2 vs. 87.3 +/- 36.2 days, p = 0.007). Among 32 male patients, the presence of SUD (n = 9, 28.1%) was associated with a less reduction in total PANSS scores (F = 7.5, p = 0.010) and higher levels of positive symptoms at the end of the treatment (12.8 +/- 4.1 vs. 18.8 +/- 7.4, p = 0.006, d = 1.0). Synthetic cannabinoids were the most common substance type used among males with treatment-refractory EOS (25.0%). Conclusions: Our results did not support the role of sociodemographic variables in clozapine response. Positive symptoms and SUD yielded a prognostic value in patients receiving clozapine
The Calculation of Mass Attenuation Coefficients of Well-Known Thermoluminescent Dosimetric Compounds at Wide Energy Range
No full text32nd International Physics Congress of Turkish-Physical-Society (TPS) -- SEP 06-09, 2016 -- Bodrum, TURKEYThe photon mass attenuation coefficients of LC BaSO3, CaCO3 and CaSOzi thermoluminescent dosimetric compounds at 100; 300; 500; 600; 800; 1,000; 1,500; 2,000; 3,000 and 5,000 keV gamma-ray energies were calculated. For this purpose, FLUKA Monte Carlo (MC) program which is one of the well-known MC codes was used in this study. Furthermore, obtained results were analyzed by means of ROOT program. National Institute of Standards and Technology (NIST) values were also used to compare the obtained theoretical values because the mass attenuation values of the used compounds could not found in the literature. Calculated mass attenuation coefficients were highly in accordance with the NIST values. As a consequence, FLUKA was successful in calculating the mass attenuation coefficients of the most used thennoluminescent compound.Turkish Phys SocEge UniversityEge University [2014 FEN 026]The Author thanks to Dr. E. Pilicer for his help in the calculation procedure and to Dr. C. Celiktas for his precious contribution to the study. This work was supported by Scientific Research Project of Ege University under Project No. 2014 FEN 026
Longitudinal Course of Depressive, Anxiety, and Posttraumatic Stress Disorder Symptoms After Heart Surgery: A Meta-Analysis of 94 Studies
No full textOBJECTIVE: This study aimed to analyze the longitudinal course of depression, anxiety, and posttraumatic stress disorder (PTSD) symptoms in patients with cardiac disease after heart surgery (HS).METHODS: We conducted a systematic review and random-effects meta-analysis of cohort studies in patients undergoing HS, measuring anxiety, depressive, and PTSD symptoms before and at least 30 days thereafter. Subgroup and meta-regression analyses, investigation of publication bias, and quality assessment were undertaken.RESULTS: We included 94 studies relating to 15,561 patients. HS included coronary artery bypass graft surgery, valve replacement, implantable cardioverter-defibrillator placement, left ventricular assist device placement, heart transplantation, and other types of HS. Across studies, symptoms of depression (g = 0.32; 95% confidence interval [CI] = 0.25 to 0.39; p < .001) and anxiety improved after HS (g = 0.52; 95% CI = 0.43 to 0.62; p < .001), whereas PTSD symptoms worsened (g = -0.42; 95% CI = -0.80 to -0.04; p = .032). The reduction of depression and anxiety levels was more pronounced for patients with underlying coronary artery disease and heart failure and persisted for 1 year after HS, whereas the increase in PTSD symptoms returned to baseline after 6 months. Depression improvement was inversely associated with older age, diabetes, hypertension, and dyslipidemia and positively with baseline heart failure. No additional clinical or demographic variables were associated with the course of anxiety symptoms. Quality of included studies was low overall. Publication bias was nonsignificant.CONCLUSIONS: Depressive and anxiety symptoms improve for 1 year after HS, whereas PTSD symptoms might worsen. Older patients and those with metabolic comorbidities, valve disease, or ventricular arrhythmias are at higher risk for continued depressive and anxiety symptoms and should be monitored closely
