1,721,129 research outputs found
Catalysis: The pharmaceutical perspective
No full textThe striking impact of enzymatic and organometallic catalysis on the design of environmentally friendly processes for the discovery and production of pharmaceutical products is discussed. Four case studies namely ST1535, Idarubicin, Rubitecan and 7ACA are analysed in the context of a modern synthetic design based on the application of the 12 green chemistry principles. (C) 2008 Elsevier B.V. All rights reserved
Catalysis: A key technology for a green approach to pharmaceutical production
No full textLa catalisi: tecnologia fondamentale per it design di processi industriali a basso impatto ambientale nell'industria farmaceutica. La catalisi è la tecnologia fondamentale per lo sviluppo di processi industriali «green», efficienti e a basso costo per la produzione di idarubicina, erlotinib e ivermectina, dimostra il ruolo centrale dei processi catalitici.Catalysis is the key technology for the development of green processes for the industrial production of active pharmaceutical ingredients. The design of green, efficient and cost competitive industrial process of idarubicin, erlotinib and ivermectin shows the central role of catalysis
Present and Future of Industrial Pharmaceutical Industries in Italy
No full textThe Future of Pharma INdustr
fight against Onchocerchiasis/Lymphatic Filiaris and Malaria. Avermectin ans Artemisinin, Lead Compound from Nature
No full textCatalysis as a Key Technology for the Development and Implementation of Cost-Competitive and Sustainable Production of Active Pharmaceutical Ingredients (APIs)
No full textCatalysis plays a central role in the synthesis of active pharmaceutical ingredients
(APIs), offering enhanced efficiency, selectivity, and sustainability in modern
pharmaceutical manufacturing. The demand for greener and more cost-effective
synthesis routes has positioned catalytic methods—particularly asymmetric, enzymatic, and transition-metal catalysis—at the
forefront of pharmaceutical innovation. This article explores the various types of catalysis used in API production, discusses
process design considerations, and highlights future perspectives for catalysis in the pharmaceutical sector
A Process For The Preparation Of Xylene Linked Cyclam Compounds
No full textThe present invention relates to an improved process for the preparation of xylene linked cyclam compounds. More particularly the invention provides a process for preparation of high purity plerixafor which does not involve the use of expensive chemicals, hazardous reagents or tedious purification techniques. Invention also provides novel intermediate useful for preparation of desired compound in high purity
Polymorphic Forms Of Afatinib Free Base and Afatinib Dimaleate
No full textThe present invention relates to crystalline forms of Afatinib and its dimaleate salt. The present invention also relates to processes for the preparation of crystalline forms of Afatinib and its dimaleate salt. The present invention further relates to pharmaceutical compositions of such crystalline forms of Afatinib dimaleate and use thereof in the treatment of a patient in need thereo
Industrial Synthesis Design With Low Environmental Impact In The Pharma Industry
No full textThe key concepts of industrial process design are discussed. Two industrial synthesis of 7ACA and Erlotinib hydrochloride centred on the use of enzymatic and organometallic catalysis are described
Polymorphism, Patent and Legal Battles: Science or Fiction?
No full textpolimorhisms represent one of the most critical and controversial area of drug patent
- …
