172,370 research outputs found
La ricerca pedagogico-musicale del Dipartimento delle Arti e del "Saggiatore musicale"
La ricerca scientifica in Pedagogia e Didattica della musica del Dipartimento delle Arti e del «Saggiatore musicale» si sviluppa su due fronti: la ricerca pura, teorica e metodologica, sui processi d’insegnamento e apprendimento della musica, e la ricerca applicata, che consiste nella declinazione degli esiti della ricerca pura sul terreno di un fitto, denso e intenso lavoro interistituzionale – chi si occupa di Pedagogia non può non confrontarsi in modo diretto con la società – nonché nell’organizzazione di svariate attività
Inquinamento musicale - una questione di civiltà
L'articolo affronta il problema dell'inquinamento musicale quale caso particolare dell'inquinamento acustico, problema assai avvertito nella società moderna. Esso studia l'inquinamento musicale rispetto alle funzioni assegnate ai vari tipi di musica diffusi nei luoghi pubblici, alla normativa che in Italia disciplina il fenomeno dell'inquinamento acustico, ai problemi di salute che tale specifica forma di inquinamento determina e ai fondamenti dell'ecologia urbana e umana. Di conseguenza, evidenzia i cambiamenti nelle abitudini di ascolto della musica stessa e si concentra sull'importanza del silenzio in una nuova accezione, cioè nel significato di ambiente disponibile, spazio non programmabile, condizione ideale per un "vero" ascolto, consapevole, intelligente e critico. Sottolinea, infine, che il problema dell'inquinamento musicale si pone su un piano ampio, quello dei valori culturali e morali della nostra società, per cui il fenomeno da considerarsi, alla radice, una questione di civiltà
Bienvenue à Anna Cuomo
Bienvenue à Anna Cuomo – Ongi Etorri Anna Cuomo rejoint l'équipe de l'Institut ARI en tant que Post-doctorante en contrat CNRS. En 2018, elle a soutenu à l'Ecole des Hautes Etudes en Sciences Sociales (EHESS, Paris) sous la direction de Michel Agier une thèse de doctorat intitulée : "La fabrique d'un rap africain : création, engagement et cosmopolitisme à Ouagadougou, Burkina Faso". Cette thèse d’exception s’est vue décerner le Prix 2019 Fondation Martine Aublet – Musée du Quai Branly. Anna C..
Error analysis of a Collocation method for numerically inverting a Laplace transform in case of real samples
In [S. Cuomo, L. D’Amore, A. Murli, M.R. Rizzardi, Computation of the inverse Laplace transform based on a collocation method
which uses only real values, J. Comput. Appl. Math., 198 (1) (2007) 98–115] the authors proposed a Collocation method (C-method)
for real inversion of Laplace transforms (Lt), based on the truncated Laguerre expansion of the inverse function. The computational kernel
of a C-method is the solution of aVandermonde linear system, where the right hand side is obtained evaluating the Lt on the real axis.
The Bjorck Pereira algorithm has been used for solving the Vandermonde linear system, providing a computable componentwise
error bound on the solution.
For an inversion problem on discrete data F is known on a pre-assigned set of points (we refer to these points as samples of F) only
and the major challenge is to deal with a significative loss of information.A natural approach to overcome this intrinsic difficulty is
to construct a suitable fitting model that approximates the given data. In this case, we show that such approach leads to a C-method
with perturbed right hand side, and then we use again the Bjorck Pereira algorithm.
Starting from the error introduced by the fitting model, we study its propagation in order to determine the maximum attainable
accuracy on fN. Moreover we derive a computable error bound that allows to get the suitable value of the parameter N that gives
the maximum attainable accuracy
14) GIUSTINO A., CUOMO V., MARSDEN C.A., Maternal cocaine exposure alters mesolimbic dopaminergic function in rat offspring. Eur. J. Pharmacol. 345, 175-180, 1998
Error analysis of a Collocation method for numerically inverting a Laplace transform in case of real samples
In [S. Cuomo, L. D’Amore, A. Murli, M.R. Rizzardi, Computation of the inverse Laplacetransform based on acollocationmethod which uses only real values, J. Comput. Appl. Math., 198 (1) (2007) 98–115] the authors proposed aCollocationmethod (C-method) for real inversion of Laplacetransforms (Lt), based on the truncated Laguerre expansion of the inverse function.
The computational kernel of a C-method is the solution of a Vandermonde linear system, where the right hand side is obtained evaluating the Lt on the real axis. The Bjorck Pereira algorithm has been used for solving the Vandermonde linear system, providing a computable componentwise error bound on the solution.
For an inversion problem on discrete data F is known on a pre-assigned set of points (we refer to these points as samples of F) only and the major challenge is to deal with a significative loss of information. A natural approach to overcome this intrinsic difficulty is to construct a suitable fitting model that approximates the given data. In this case, we show that such approach leads to a C-method with perturbed right hand side, and then we use again the Bjorck Pereira algorithm.
Starting from the error introduced by the fitting model, we study its propagation in order to determine the maximum attainable accuracy on fN. Moreover we derive a computable error bound that allows to get the suitable value of the parameter N that gives the maximum attainable accurac
MAC principles for an Ultra Wide Band wireless access
The Ultra Wide Band (UWB) radio is becoming a promising field for the design of digital communications systems of new conception. This technique, mainly based on the Impulse Radio paradigm, offers great flexibility and enormous potentiality in view of a broadband wireless access. This paper presents the main principles for the development of a multi-access scheme based on the UWB. The principles for the definition of a distributed medium access control for mobile computing applications are described as well as the detailed functional model involved in the capacity-sharing procedures
Analysis and synthesis of self-synchronizing chaotic systems
Includes bibliographical references (p. 225-228).Supported by the U.S. Air Force Office of Scientific Research. AFOSR-91-0034-C Supported by the U.S. Navy Office of Naval Research. N00014-91-C-0125 N00014-93-1-0686 Supported by Lockheed Sanders, Inc.Kevin M. Cuomo
The Ubiquitination of UFL1 by the APC/C complex may affect the DNA repair pathway choice
DNA double-strand breaks (DSBs) are the most toxic DNA lesions contributing to genome instability. DSBs can be mainly repaired by homologous recombination (HR) and non- homologous end-joining (NHEJ). By exploring the role of an isoform of the multifunctional cyclin-dependent kinase 9, CDK9-55, we identified the cell division cycle 23 protein as a new substrate, with Ser588 being its putative phosphorylation site, upon DNA damage. CDC23 is subunit of the Anaphase-promoting complex/cyclosome (APC/C), a multimeric E3 ubiquitin ligase complex involved in DNA repair. We observed by mutating the CDC23 in the Serine target of CDK9-55 phosphorylation, a defect in the repair pathway choice observing an impairment in HR. Through LC/MS analysis we identified the UFM1 specific ligase 1 (UFL1) as a new target of the APC/C-CDC23(S588A) during DNA damage. Recently, UFL1, the only known E3-like ligase that mediates the UFMylation process, was demonstrated to be involved in HR pathway as part of ATM activation. We demonstrated how the poly-ubiquitination of UFL1, mediated by the APC/C-CDC23 complex upon DSBs, does not lead to its proteasomal degradation but probably involved in its cellular localization change. The recognition of target substrates by the APC/C complex depends on the specificity of two co-activators, Cell Division Cycle 20 (CDC20) and Fizzy and Cell Division Cycle 20 Related 1 (FZR1 or CDH1), which bind degron motifs in the substrate’s sequences, named ABBA-BOX and D-BOX, respectively. We investigated the presence of these recognition motifs and identified both putative ABBA-BOX and D-BOX domains in UFL1 protein sequence. Our preliminary data describe a possible new regulation of the repair pathway choice between HR and NHEJ upon DSB formation, suggesting the potential role of the APC/C in selecting the appropriate repair pathway possibly by regulating UFL1 protein polyubiquitination. Moreover, these results represent further evidence of the key role of the UFMylation process in the activation of Homologous recombination. These findings pave the way for new biomarkers as well as new potential therapeutic approaches in cancer treatment
- …
