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Prediction Models for Cardiac Risk Classification with Nuclear Cardiology Techniques
Full text linkRegression modeling strategies are increasingly used for the management of subjects with cardiovascular diseases as well as for decision-making of subjects without known disease but who are at risk of disease in the short- or long-term or during life span. Accurate individual risk assessment, taking in account clinical, laboratory, and imaging data is useful for choosing among prevention strategies and/or treatments. The value of nuclear cardiology techniques for risk stratification has been well documented. Many models have been proposed and are available for diagnostic and prognostic purposes and several statistical techniques are available for risk stratification. However, current approaches for prognostic modeling are not perfect and present limitations. This review analyzes some specific aspects related to prediction model development and validation
FDG imaging should be considered the preferred technique for accurate assessment of myocardial viability
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Dilated cardiomyopathy. Role of radioisotope technics | Cardiomiopatia dilatativa. Ruolo delle tecniche radioisotopiche
No full textResponse by Spinelli et al to Letter Regarding, "Early Cardiac Involvement Affects Left Ventricular Longitudinal Function in Females Carrying α-Galactosidase A Mutation: Role of Hybrid Positron Emission Tomography and Magnetic Resonance Imaging and Speckle-Tracking Echocardiography"
No full textHemodynamic effects of the antihypertensive treatment with atenolol plus chlortalidone in fixed combination: A double-blind crossover comparison with atenolol
No full textTwenty patients with mild or moderate essential hypertension participated in a double-blind crossover randomized trial aimed at assessing, by echocardiography, the hemodynamic effects of the antihypertensive therapy with atenolol administered once daily (100 mg) alone or combined with chlortalidone (25 mg) in fixed combination. Blood pressure and heart rate were measured at rest and during bicycle exercise before and after four-week periods of treatment. Both atenolol and atenolol plus chlortalidone reduced significantly blood pressure and heart rate. The reduction in blood pressure was mediated by a reduction in cardiac output. However, the combined treatment was also able to prevent the increase in stroke volume observed after atenolol alone. Furthermore, the combined treatment was able to significantly lower blood pressure during exercise, while atenolol alone failed. These results suggest that the association of chlortalidone potentiates the antihypertensive effect of atenolol by acting through a different mechanism
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