1,721,185 research outputs found
Powerful Ultrasound in Metal-Asisted Synthesis: From Classical Barbier-Like Reactions to Click Chemistry
No full textDehydrative alkylation of alcohols with triethyl methanetricarboxylate under Mitsunobu conditions
No full textPalladium-catalysed coupling between allyl carbonates and triethyl methanetricarboxylate (TEMT)
No full textTriethyl methanetricarboxylate (TEMT) is allylated by allylic carbonates in the presence of catalytic amounts of Pd(0) complexes; the reaction, conducted in very mild conditions, is fast and gives high yields of the title products
OXYGENATED SESQUITERPENOIDS FROM A NONPOISONOUS SARDINIAN CHEMOTYPE OF GIANT FENNEL (FERULA COMMUNIS)
No full textTHE REACTIVITY OF 4-HYDROXYCOUMARIN UNDER HETEROGENEOUS HIGH-INTENSITY SONOCHEMICAL CONDITIONS
No full textOxygenated sesquiterpenoids from a nonpoisonous Sardinian chemotypes of giant fennel (Ferula communis)
No full textHighly Active Cranberry's Polyphenolic Fraction: New Advances in Processing and Clinical Applications
Full text linkCranberry is a fruit originally from New England and currently growing throughout the east and northeast parts of the USA and Canada. The supplementation of cranberry extracts as nutraceuticals showed to contribute to the prevention of urinary tract infections, and most likely it may help to prevent cardiovascular and gastroenteric diseases, as highlighted by several clinical trials. However, aiming to validate the efficacy and safety of clinical applications as long-term randomized clinical trials (RCTs), further investigations of the mechanisms of action are required. In addition, a real challenge for next years is the standardization of cranberry's polyphenolic fractions. In this context, the optimization of the extraction process and downstream processing represent a key point for a reliable active principle for the formulation of a food supplement. For this reason, new non-conventional extraction methods have been developed to improve the quality of the extracts and reduce the overall costs. The aim of this survey is to describe both technologies and processes for highly active cranberry extracts as well as the effects observed in clinical studies and the respective tolerability notes
Advances in Technologies for Highly Active Omega-3 Fatty Acids from Krill Oil: Clinical Applications.
Full text linkEuphausia superba, commonly known as krill, is a small marine crustacean from the Antarctic Ocean that plays an important role in the marine ecosystem, serving as feed for most fish. It is a known source of highly bioavailable omega-3 polyunsaturated fatty acids (eicosapentaenoic acid and docosahexaenoic acid). In preclinical studies, krill oil showed metabolic, anti-inflammatory, neuroprotective and chemo preventive effects, while in clinical trials it showed significant metabolic, vascular and ergogenic actions. Solvent extraction is the most conventional method to obtain krill oil. However, different solvents must be used to extract all lipids from krill because of the diversity of the polarities of the lipid compounds in the biomass. This review aims to provide an overview of the chemical composition, bioavailability and bioaccessibility of krill oil, as well as the mechanisms of action, classic and non-conventional extraction techniques, health benefits and current applications of this marine crustacean
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