1,721,073 research outputs found
Contrast-enhaced computed tomography as a prognostic indicator os sepsis in necrotizing pancreatisis
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Atypical primary Burkitt lymphoma of the tyroid gland: a pratical approach for differential diagnosis and management
No full textPrimary thyroid lymphomas are rare diseases that continue to produce diagnostic and therapeutic
dilemmas. Among these, Diffuse Large B-Cell Lymphoma (DLBCL) represents the more common
subtype while Burkitt lymphoma (BL) is unusual. Distinguishing between BL and DLBCL is
critical as the two disease require different therapeutic management. Diagnostic accuracy is therefore
essential to obtain patient safety.
Here, we described the second case of Burkitt Lymphoma of the thyroid gland reported in the
English literature, investigate the differential diagnosis and explore the diagnostic approach that
might be used when neoplasia with morphological features intermediate between BL and DLBCL
happens on pathologist’s practice.
A 56-year-old women presented to our attention for the evaluation of a rapidly growing neck mass
causing compressive symptoms. Ultrasound examination demonstrated two hypoechogenic nodules
within a diffusely enlarged thyroid gland. Histological analysis showed cells resembling DLBCL, as
well as starry sky pattern and immunohistochemical pattern suggestive of BL. The final diagnosis
of BL was confirmed by FISH analysis that demonstrated c-myc-IgH rearrangement with t(8;14)
translocation.
This study demonstrates that no single parameter alone (such as morphology, genetics analysis or
immunophenotyping) can be used as gold standard for the diagnosis of BL, but a combination of
several diagnostic techniques is necessary for an optimal practical approach. Since treatment regimens
for BL and DLBCL differ significantly, we believe that our study should be useful to suggest
the correct diagnostic algorithm to be used when a case of BL, with unusual localization and ambiguous
morphological features, is encountered in routine setting
Resection therapy in the treatment of intrahepatic biliary lithiasis
No full textThe authors report a case of intrahepatic lithiasis in a patient already operated of cholecystectomy and without lithiasis of the common bile duct. The lithiasis was present in the left lateral bile duct, was multiple and trapped behind a very narrow stricture. The stones were associated with a marked dilatation of the involved biliary ducts, cholangitis, fibrosis and atrophy of surrounding hepatic parenchyma. It was performed a resection of the II and III hepatic segments and the patient recovered completely and is well and disease free after one year. The authors believe, also on the base of the data reported by others, that in the intrahepatic lithiasis with strictures of the bile intrahepatic ducts the hepatic resection is the treatment of choice, especially when the lithiasis is present in a sectorial or segmental bile duct, preventing any stone recurrence
Octreotide an anlog of somatostatin and gabexate ,esylate in human pancreatic juice samples measured by HPLC-DAD-FL detection
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Pancreatico-jejunal anastomosis in the treatment of chronic pancreatitis and calculosis of the Wirsung's duct
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