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Development of biocompatible materials for the immobilization of macromolecules of pharmaceutical interest
Full text linkUn raro modello di cromosomi sessuali atipici in Acomys selousi (Rodentia, Muridae) dalla Tanzania
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A note on three new karyotypes of Lophuromys flavopunctatus sensu lato (Rodentia, Muridae) from Tanzania
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Molecular and karyological homogeneity in Trachylepis striata (Peters 1844) and Trachylepis wahlbergii (Peters 1869) (Scincidae Reptilia).
No full textA new chromosomal race of the house mouse - Mus musculus domesticus - in the Vulcano Island - Aeolian Archipelagos, Italy.
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The origin of an unusual sex chromosome constitution in Acomys sp (Rodentia, Muridae) from Tanzania
No full textThis paper describes a case which presents an evident variation from the "standard" XX/XY sex chromosomal constitution in a rodent, Acomys sp. This species known to be found in three localities of East Africa has only recently been separated from A. spinosissimus, its closest relative. In our study, five specimens of Acomys sp. and eight specimens of A. spinosissimus were live-trapped in five localities. Comparisons between the two taxa assed by G- banding show a complete homology in the chromosomal shape and banding pattern for 29 pairs of chromosomes corresponding to the complete autosomal set of A. spinosissimus. However, while all the A. spinosissimus analysed have 2n = 60 and a XY-XX system, in Acomys sp. males and females constitute mosaics for sex chromosomes in the bone marrow cells. Females (2n = 59, 60) have an excess (97%) of aneuploid cells with one single giant X chromosome, and males (2n = 60, 61) show X0/XY cells occurring in somatic tissues and XY cells in the germinal lineage. In addition, an odd heterochromatic submetacentric chromosome was identified in all the cells examined in two males and a female of Acomys sp. Since this chromosome was not related to sex determination and it is not present in all the analysed specimens, it can be considered as a B chromosome. Finally, the in situ fluorescence hybridisation (FISH) with telomeric probes showed a very intense interstitial telomeric signal (ITS) at the medial part on the long heterochromatic arm of the X chromosome. This could be due to recent chromosomal rearrangement
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