1,721,098 research outputs found
The cardiolipin analogues of Archaea
No full textAbstractThe present article reviews studies of the structure and functional roles of the cardiolipin analogues of extremely halophilic prokaryotes belonging to the Archaea domain. Analogies and differences between the archaeal bisphosphatidylglycerol and the mitochondrial cardiolipin are presented. Furthermore the structure of archaeal glycophospholipid dimers is illustrated together with the available information on their function. The studies on the function of cardiolipin analogues in archaebacteria point out the tight interaction established by these phospholipids with membrane proteins and their role as bioactive lipids in the adaptation of microorganisms to osmotic stress
Cardiolipin as key lipid of mitochondria in health and disease. 2nd Edition, Florence, Italy, September 30-October 1, 2015
No full textThe second edition of the workshop dedicated to cardiolipin, the signature lipid of mitochondria, was held as a satellite meeting of the 13th Euro Fed Lipid international congress in Florence, Italy, at the end of September 2015. During the workshop various aspects of basic cardiolipin functions in biomembranes of prokaryotes and animal cells were discussed, highlighting connections between cardiolipin research and human physiology in particular. Alteration of the cardiolipin species pattern and a parallel increase of monolysocardiolipin is the hallmark of Barth syndrome, an X linked genetic disease. Furthermore literature reports suggest the involvement of cardiolipin in other pathologies associated with an imbalance in bioenergetic functions, such as diabetes. The Cardiolipin Workshop was a low budget meeting sponsored by the University of Bari Aldo Moro and the Barth Syndrome Foundation. The organizers are grateful to the invited speakers, poster presenters and chairpersons as they supported the meeting by sustaining their travel and lodging expenses. Before the starting of the scientific sessions, the families of Italian boys affected by Barth syndrome (recently affiliated with the Barth Syndrome Foundation, USA) could meet scientists, biologists and pediatricians involved in research, diagnosis and cure of the disease. The family meeting was chaired by Daniela Toniolo, who discovered the tafazzin gene in 1997
The role of potassium and chloride ions on the Na+/acidic amino acid cotransport system in rat intestinal brush-border membrane vesicles
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Reconstitution of olfactory receptors in lipid bilayers as a tool for the construction of artificial nose to detect mines
No full textMeeting report. Cardiolipin as key lipid of mitochondria in health and disease. Bari September 17, 2013
No full textThe idea of a Cardiolipin workshop in Italy came to the meeting organizers in June 2011, during the minisabbatical of Angela Corcelli in New Yok City in the laboratory of Michael Schlame. They thought to take advantage of the presence of the 54th International Conference on the Bioscience of Lipids (ICBL) in Bari in 2013 to organize the Cardiolipin workshop as a satellite event. The web page of the Cardiolipin Meeting was kindly supported by the Eurofedlipid organization. About 60 scientists attended the meeting focused on the multiple roles of cardiolipin in mitochondria in physiological and pathological states in variuos organisms as well as in bacterial membranes. In addition to ICBL participants, many students and colleagues of the Universities of Bari and Lecce attended the meeting, increasing the number of total participants to about 100. As defects in cardiolipin metabolism may cause Barth Syndrome, the meeting also presented an occasion to establish contacts between the nascent Italian Barth Syndrome Foundation and scientists actively involved in cardiolipin research
Role of phospholipids in the binding of bumetanide to the rabbit parotid Na/K/Cl cotransporter
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