196,143 research outputs found

    Transient deep and giant negative T waves in dogs with myocardial injury

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    Introduction: Although transient deep and giant negative T waves (NTWs) may develop during myocardial injury (MI) in humans, no data exist on this repolarization abnormality in canine MI. Therefore, this study aimed to describe the occurrence of transient deep/giant NTWs in dogs with MI. Animals, Materials and Methods: Medical records were retrospectively searched to identify dogs with MI and transient deep/giant NTWs. Signalment, history, and selected diagnostic test results were reviewed. Data analysis was descriptive. Results: Six cases were diagnosed with MI associated with deep (n = 1) and giant (n = 5) transient NTWs. Myocardial injury was classified as acute in all cases and was due to snake envenomation (n = 3), sepsis (n = 2), and systemic inflammatory response syndrome (n = 1). At the time of deep/giant NTWs identification, all dogs had elevated cardiac troponin I and ≥1 echocardiographic abnormality of the left ventricular structure and/or function. Moreover, all dogs with giant NTWs had prolonged QT intervals. After the MI resolution, T-wave polarity and QT-interval duration became normalized in all dogs. Moreover, left ventricular morphological and functional parameters were completely normalized in four dogs. In contrast, ventricular echogenicity remained heterogeneous in two dogs, despite otherwise normalized ventricular parameters. Five dogs were still alive at the conclusion of the study. Conclusions: Transient deep/giant NTWs may develop in dogs with acute MI and T-wave polarity changes seem to occur synchronously with the evolution of myocardial damage. Moreover, transient deep/giant NTWs seem associated with a favorable prognosis in canine MI

    Atrial septal defect in five dogs

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    The clinical, electrocardiographic, radiographic, and two-dimensional, M-mode and Doppler echocardiographic findings of five cases of canine ostium secundum type atrial septal defect (ASD) are described. The atrial septal anomaly was associated with other congenital cardiac abnormalities in two dogs: ventricular septal defect in one case and tricuspid dysplasia in the other. ASD was found in addition to dilated cardiomyopathy and suspected atrial thrombosis in one geriatric dog, but was the only cardiac abnormality detected in the remaining two dogs. Colour Doppler imaging facilitated the diagnosis of ASD in all subjects. The long-term prognosis for dogs with isolated and small-sized ASD is usually good, but can be compromised by the presence of concurrent congenital or acquired cardiac diseases

    Aorticopulmonary Septal Defect in a German Shepherd Dog

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    A 2-year-old, female German shepherd dog was referred with a 2-month history of dyspnea, ascites, and anorexia. On physical examination, an arrhythmia, tachypnea, and a continuous grade V/VI heart murmur were evidenced. Atrial fibrillation anti tall R waves were noted on electrocardiography. Survey thoracic radiography revealed generalized cardiomegaly and enlarged pulmonary vessels. Echocardiography demonstrated severe dilatation of the left atrium and ventricle with reduced fractional shortening. Doppler echocardiography showed continuous and turbulent flow in the ascending aorta between the aorta and the pulmonary artery. Necropsy demonstrated an aorticopulmonary septal defect
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