1,721,018 research outputs found
Evidence of colocalization between neuronal NO synthase and arginin-vasotocin in the neurosecretory neurons of a teleost
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Morphology and immunohistochemistry of the caudal neurosecretory system in tetraodontids
No full textColocalization of neuronal nitric oxide synthase with arginine-vasotocin in the preoptic-hypothalamo-hypophyseal system of the teleost Oreochromis niloticus
No full textThis study provides evidence that, in the preoptic–hypothalamo–hypophysial system of the teleost Oreochromis niloticus, several subpopulations of arginine–vasotocin (AVT)-producing neurons and neurosecretory fibers terminals express neuronal nitric oxide synthase (nNOS)-like molecules. The co-localization between nNOS and AVT was demonstrated by means of double immunofluorescence staining with the confocal microscope. This study is the first to provide evidence that nNOS may be co-localized with AVT in neurons of a nonmammalian vertebrate
Colocalization of neuronal NO synthase with urotensins I and II in the caudal neurosecretory neurons and the urophysis of the teleost Oreochromis niloticus. A gold immunoelectron microscopic study
No full textMorphology and immunohistochemistry of the caudal neurosecretory system of a marine euryhaline fish, Dicentrarchus labrax, acclimated to low salinity
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Colocalization of neuronal NO synthase with neuropeptides in preoptic and caudal neurosecretory neurons of a teleosts
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Fish Synucleins: An Update
Full text linkSynucleins (syns) are a family of proteins involved in several human neurodegenerative diseases and tumors. Since the first syn discovery in the brain of the electric ray Torpedo californica, members of the same family have been identified in all vertebrates and comparative studies have indicated that syn proteins are evolutionary conserved. No counterparts of syns were found in invertebrates suggesting that they are vertebrate-specific proteins. Molecular studies showed that the number of syn members varies among vertebrates. Three genes encode for α-, β- and γ-syn in mammals and birds. However, a variable number of syn genes and encoded proteins is expressed or predicted in fish depending on the species. Among biologically verified sequences, four syn genes were identified in fugu, encoding for α, β and two γ (γ1 and γ2) isoforms, whereas only three genes are expressed in zebrafish, which lacks α-syn gene. The list of "non verified" sequences is much longer and is often found in sequence databases. In this review we provide an overview of published papers and known syn sequences in agnathans and fish that are likely to impact future studies in this field. Indeed, fish models may play a key role in elucidating some of the molecular mechanisms involved in physiological and pathological functions of syn proteins
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