958,656 research outputs found

    Edward C. M. Chen, oral history interview and transcript

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    This recording and transcript form part of a collection of oral history interviews conducted by the Chao Center for Asian Studies at Rice University. This collection includes audio recordings and transcripts of interviews with Asian Americans native to Houston.Edward C. M. Chen, interviewed by Juean Chen and Clarissa Cox, June 4, 2010, in Houston, Texas

    Original immunoblots Ouyang and Chen et al Developmental Cell

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    Uncropped immunoblotting images Ouyang and Chen Developmental Cell

    Chen, C. S.

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    Overexpression of Cyclin D1 and C-Myc Gene Products in Human Primary Epithelial Ovarian Cancer

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    Cyclin D1 and c-Myc are key participants in the cell-cycle pathway, in which aberrancies have been associated with malignant transformation. To date, data on the relationship of expression of these proteins and histologic subtype of epithelial ovarian cancer are still scarce and discordant. Immunohistochemical analysis was performed on 12 normal ovaries and 47 cases of serous, mucinous, endometrioid, and clear cell ovarian carcinomas. No abnormal expression of cyclin D1 or c-Myc was demonstrated in any of the 12 normal ovarian specimens. However, compared to normal ovarian tissues, overexpression of cyclin D1 and c-Myc was observed in 42.6% (20/47) and 65.9% (31/47) of tumors examined, respectively. There was no significant difference of overexpression of cyclin D1 or c-Myc gene products between these four histologic subtypes of ovarian adenocarcinomas. This study shows that cyclin D1 and c-Myc are frequently overexpressed in epithelial ovarian carcinomas, but they are not correlated with a particular histologic subtype. Although our preliminary results need to be validated in a larger number of tumors, the abnormal expression of cyclin D 1 and c-Myc in epithelial ovarian cancer reaffirms the notion that they are crucial components in the pathway of tumorigenesis and deserve further study

    Supporting data used in the paper: Xi Chen, 2020, The LMARS based shallow-water dynamical core on generic gnomonic cubed-sphere geometry

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    # Simulation results of the unstaggered shallow water model This repository contains the supporting data used in the paper: Xi Chen, 2020, The LMARS based shallow‐water dynamical core on generic gnomonic cubed‐sphere geometry, DOI: 10.1029/2020MS002280 Organization of the repository: The tar archive with this data submission has a: doc directory contains a README.md with information regarding naming conventions to label the model configurations for a shallow water test simulation. Additional information can also be found in README.md. Table 4 in the paper provides additional details. The data directory contains the supporting data files (NetCDF format).Disclaimer: "This was prepared by Xi Chen under award NA18OAR4320123 from the National Oceanic and Atmospheric Administration, U.S. Department of Commerce. The statements, findings, conclusions, and recommendations are those of the author(s) and do not necessarily reflect the views of the National Oceanic and Atmospheric Administration, or the U.S. Department of Commerce.

    C. C. Chen, 1918

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    C. C. Chen, first Chinese student to attend the University of Maryland, 1918

    Celebration of the Life of Edward K. T. Chen

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    Edward C. M. Chen is the son of Edward K. T. Chen
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