117,547 research outputs found
Solitary cerebral metastasis from ovarian carcinoma: report of 4 cases
No full textFour cases of solitary cerebral metastasis from ovarian carcinoma are reported. Although systemic metastases from this type of tumor are frequent, they rarely affect the nervous system. From the 4 cases presented and a review of the literature, it appears that a better outcome may be obtained by a combined treatment of the cerebral metastasis, comprising surgery, radiotherapy and chemotherapy
Carcinoma of the prostate: brain stem metastasis as the only site of spread.
No full textAIMS AND BACKGROUND:
Metastasis to the brain from prostate carcinoma is a rare event; it is reported in less than 4% of postmortem examinations. The prevalence of cases detected antemortem is even smaller, and the prevalence of brain stem metastasis as the only site of metastasis has been reported in only two other cases.
METHOD:
The authors present a third such case.
RESULTS:
A 55-year-old man, treated for an adenocarcinoma of the prostate (prostatectomy and radiotherapy), started to complain of facial expression disturbances and headaches 2 years later. Physical examination showed a left VII cranial nerve palsy. MRI showed an enhancing mass in the pons. Total body CT was negative. The patient was treated with a course of whole-brain and brain stem radiotherapy following stereotactic biopsy. Four months after radiotherapy, the neurological symptoms had disappeared and the patient died of a myocardial infarct. The systemic disease was still clinically silent.
CONCLUSION:
Our case involved only brain stem metastasis, probably implicating Batson's direct route of the paravertebral venous pathway
Association of breast carcinoma and meningioma: report of nine new cases and review of the literature.
No full textNine patients with diagnosed breast cancer who developed meningiomas are reported. Articles suggesting that an association of these two tumors is possible. Some authors have noted hormonal sensitivity and the presence of hormonal receptors in some meningiomas. Since breast cancer is the most common tumor in women, an association between it and meningiomas might be fortuitous. However, it is important to fully investigate brain lesions in patients with breast cancer so that potentially curable meningiomas are not considered as metastases
Solitary plasmacytoma of the calvarium: a review of clinical and prognostic features.
No full textPrimary craniocerebral plasmacytomas are uncommon they represent only 0.7% of all plasmacytomas. We report one case of solitary plasmacytoma of the skull and discuss the clinical features and prognosis of this tumor. There seems to be no difference in prognosis between plasmacytomas originating from the bone (osseous form) and those originating from the dura mater (non-osseous form). In these lesions, the risk of secondary multiple myeloma appears to be low
Fascite della volta cranica: considerazioni cliniche su una rara lesione osteolitica
No full textThe authors describe 1 case of cranial fasciitis in adult age that presented as solitary osteolytic lesions of the skull. The difficulty in making a differential neuroradiological diagnosis with other osteolytic pathologies of the cranial vault is demonstrated
Post-radiation glioblastoma
No full textThe authors report 1 case of cerebral glioblastoma following radiotherapy. From case presented and the review of the literature, the pathological and clinical aspects of radio-induced glioblastoma are the following: 1) children appear particularly sensitive to the development of the tumor; 2) there is a male patients predominance, otherwise than is observed in spontaneous glioblastomas; 3) these tumors present a peak frequency in third decade of life
Medulloblastoma in late adults. Case report and critical review of the literature.
No full textBACKGROUND: Medulloblastoma in late adults (older than 65 years) is an exceptional occurrence; in fact only 8 cases are reported with complete clinical notes in the literature. METHODS: The authors describe a case of medulloblastoma occurring in a 68-year-old man and analyzed cases reported in the literature. RESULTS: The overall average age of the patients was 72.8 years (range 67-88 years), and the male prevalence of this tumour (70% of cases) seems to be unrelated to age. There is a lateral predominance in late adults (77.7% of cases). Seven patients underwent operation and subsequently these patients underwent a course of radiation therapy. Only two patient was treated with postoperative chemotherapy. Median survival for seven patients treated was 43.2 months (range 23-96 months). CONCLUSIONS: It is interesting to note that: 1) histological analysis revealed a classic type medulloblastoma (88.8% of cases) similar to the children: 2) site of the tumor is lateral similar to the adults (77.7% of cases)
Rathke's cleft cyst: a clinical and radiographic review.
No full textWe report the case of a 62-year-old woman, who had a 4-year history of progressive visual acuity deficit. On neurological examination, visual acuity was 5/20 in the right and 4/20 in the left eye. A hormonal study revealed hypophyseal hypofunction. CT and MRI scans showed an intra-suprasellar cystic lesion, hyperintense in T1 and hyperintense in T2-weighted sequences. At surgery, the cyst wall was opened and the cavity placed in communication with the subarachnoid space. Histological examination showed a Rathke's cleft cyst. After four years of follow-up the patient's visual deficit remained unchanged, whereas the results of the hormonal assays were normal. An MRI scan confirmed the absence of the cyst. We review 216 reported cases of Rathke's cyst and discuss its pathogenesis, clinical features and treatment
Solitary brain metastases from non-oat cell lung cancer: clinical and prognostic features.
No full textThe authors report 91 cases of solitary brain metastasis from non-oat cell lung cancer, 66 patients were males and 25 females; average age was 57 years (range 40-72 years). Surgical removal was total in 80 cases and partial in 11. All patients received postoperative radiotherapy and 40 chemotherapy. Histologically, the tumor was an adenocarcinoma in 51 cases (56%), a squamous cell carcinoma in 22 (24%), an undifferentiated carcinoma in 18 (20%). Median survival was 16 months and the main cause of death was progression of the primary cancer (59% of cases). Survival was influenced by staging of the primary tumor, while no prognostic significance was found regarding the type of clinical tumor onset, type of radiotherapy and the histotype of the lesion. Use of the "no internal touch" technique and brain radiotherapy reduced local brain relapse
Long-term survival in a patient with supratentorial glioblastoma: clinical considerations.
No full textGlioblastoma, a malignant tumor of neuroepithelial origin, is relatively uncommon in childhood, during which it accounts for 7%-9% of brain tumors. A few patients (about 3%) live more than 5 years. We report a 13-year-old girl who was admitted because one month earlier she had begun to present headache and diplopia. Brain computed tomography (CT) showed a right frontal tumor. At operation, complete excision of the visible tumor was performed. Histologic examination showed that the tumor was a glioblastoma multiforme. The patient underwent 52 Gy of external beam radiotherapy to the enhancing tumor mass plus 3-cm border, and chemotherapy with nitrosourea (BCNU). Fourteen years, 9 months later, the patient presents neither neurological deficits nor radiological relapse. We confirm that younger age, the one immutable prognostic factor, supports a particularly aggressive approach to the treatment of glioblastomas
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