1,721,083 research outputs found

    Solitary cerebral metastasis from ovarian carcinoma: report of 4 cases

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    Four cases of solitary cerebral metastasis from ovarian carcinoma are reported. Although systemic metastases from this type of tumor are frequent, they rarely affect the nervous system. From the 4 cases presented and a review of the literature, it appears that a better outcome may be obtained by a combined treatment of the cerebral metastasis, comprising surgery, radiotherapy and chemotherapy

    Solitary plasmacytoma of the calvarium: a review of clinical and prognostic features.

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    Primary craniocerebral plasmacytomas are uncommon they represent only 0.7% of all plasmacytomas. We report one case of solitary plasmacytoma of the skull and discuss the clinical features and prognosis of this tumor. There seems to be no difference in prognosis between plasmacytomas originating from the bone (osseous form) and those originating from the dura mater (non-osseous form). In these lesions, the risk of secondary multiple myeloma appears to be low

    Long-term survival in a patient with supratentorial glioblastoma: Clinical considerations

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    Glioblastoma, a malignant tumor of neuroepithe- lial origin, is relatively uncommon in childhood, during which it accounts for 7%-9% of brain tumors. A few patients (about 3%) live more than 5 years. We report a 13-year-old girl who was admitted because one month earlier she had be- gun to present headache and diplopia. Brain computed to- mography (CT) showed a right frontal tumor. At operation, complete excision of the visible tumor was performed. Histologic examination showed that the tumor was a glioblastoma multiforme. The patient underwent 52 Gy of ex- ternal beam radiotherapy to the enhancing tumor mass plus 3- cm border, and chemotherapy with nitrosourea (BCNU). Fourteen years, 9 months later, the patient presents neither neurological deficits nor radiological relapse. We confirm that younger age, the one immutable prognostic factor, sup- ports a particularly aggressive approach to the treatment of glioblastomas

    High-dose radiation-induced meningiomas following acute lymphoblastic leukemia in children

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    The authors review three personal cases of patients who developed cerebral meningiomas following high-dose radiotherapy for acute lymphoblastic leukemia. Two patients were female and one male. Their ages when the leukemia appeared were between 11 and 15 years. All patients were treated with a course of prophylactic irradiation to the neuraxis for a total dose of 24 Gy. After an average interval of 10.4 years, all three patients presented a meningioma; histologically, one was meningothelial and two were fibrous. All three meningiomas presented atypical features. At follow-up 1, 4, and 4 years respectively after surgery, none of these patients presents neurological deficits or neuroradiological signs of recurrence. Forty-nine cases of high-dose radiation-induced meningioma are also reviewed
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