1,720,964 research outputs found
CONNETTIVITE INDIFFERENZIATA (UCTD) DI RECENTE DIAGNOSI: PROFILO CLINICO ED IMMUNOLOGICO
CLINICAL AND IMMUNOLOGICAL ASSOCIATION WITH AUTOANTIBODIES TO CELLULAR ANTIGEN IN A COHORT OF 532 SLE PATIENTS FROM A SINGLE CENTER
Antiphospholipid antibody: laboratory, pathogenesis and clinical manifestations
Antiphospholipid antibodies (aPL) represent a heterogeneous group of antibodies that recognize various antigenic targets including beta2 glycoprotein I (β2GPI), prothrombin (PT), activated protein C, tissue plasminogen activator, plasmin and annexin A2. The most commonly used tests to detect aPL are: lupus anticoagulant (LAC), a functional coagulation assay, anticardiolipin antibody (aCL) and anti-β2GPI antibody (anti-β2GPI), which are enzyme-linked immunoassay (ELISA). Clinically aPL are associated with thrombosis and/or with pregnancy morbidity. Apparently aPL alone are unable to induce thrombotic manifestations, but they increase the risk of vascular events that can occur in the presence of another thrombophilic condition; on the other hand obstetrical manifestations were shown to be associated not only to thrombosis but mainly to a direct antibody effect on the trophoblast
LUPUS ERITEMATOSO SISTEMICO AD ESORDIO TARDIVO: CARATTERISTICHE CLINICHE ED IMMUNOLOGICHE
Belimumab for the treatment of refractory systemic lupus erythematosus: real-life experience in the first year of use in 18 Italian patients
AUMENTO DELLA PROTEINA C-REATTIVA, ANTICORPI ANTI-CCP E FATTORE REUMATOIDE NELL'ARTRITE LUPICA
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