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STUDI SPERIMENTALI SULLA DIFFERENTE AZIONE DELLE EMISEZIONI NEUROVEGETATIVE DESTRE E SINISTRE SULL'APPARATO CARDIOVASCOLARE. DIMOSTRAZIONE DI DUE TIPI DI RIFLESSI, COMUNI E SPECIALIZZATI. STIMOLAZIONE DEL PLESSO PERICAROTIDEO DESTRO E SINISTRO IN SOGGETTI CON BLOCCO DI BRANCA DESTRA.
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Effect of active postural inhibition on the circulating levels of atrial natriuretic peptide (ANP) in hypertensive patients and in normal subjects with normotensive or hypertensive parenthood
No full textThe effect of active changes in posture, from recumbency to up-right position (60 min) on the circulating levels of atrial natriuretic peptide (ANP) were studied in 52 hypertensive patients, in 30 healthy human subjects and in 24 normotensive subjects with hypertensive parents. At the end of the orthostatic challenge, plasma ANP levels were reduced by about 40% (p<0.01) in all subjects without significant differences between the three groups. This indicates that the active postural inhibition of ANP release is substantially similar in the different subjects here studied
Atrial natriuretic factor: an epidemiological study. Preliminary results
No full textWe performed an epidemiological study on the atrial natriuretic factor pattern in a young population. Subjects were recruited in the Ospedale Militare Principale of Rome among young men liable to conscription, whose hospitalization was due either to essential hypertension or to other pathologies (not influencing our study, such as headache etc.). The recruitment lead to the formation of three different groups: normotensives, normotensives with family history of hypertension (mother and/or father) and hypertensives. On the morning of the study (after 7 days of pharmacological wash-out, under a diet containing 120 mEq of Na+/die), blood samples were taken. Plasma atrial natriuretic factor, renin activity and aldosterone were assayed by RIA. Digoxin-like immunoreactive substance was assayed by a solid-phase radioimmunoassay, following the extraction of plasma. Serum creatinine, sodium, potassium and urinary sodium and potassium (24 h before the study) were assayed by standard methods. Urinary kallikrein was assayed by chromogenic substrate S-2266. So far, we have studied 60 subjects (26 hypertensives, 21 normotensives and 13 normotensives with family history) and we wish to discuss in this article the preliminary results concerning the atrial natriuretic factor and its relationship with renin activity, aldosterone and blood pressure. Our results show that the mean plasma levels of atrial natriuretic factor in the hypertensive group were higher, although not significantly, than those of the other two groups and that the normotensives with family history had slightly higher levels as compared to normotensives (Delta % = + 7.4).(ABSTRACT TRUNCATED AT 250 WORDS
DIMOSTRAZIONE SPERIMENTALE DELL'ESISTENZA DI UNA REGOLAZIONE NEUROVEGETATIVA VAGALE DELL'INOTROPISMO CARDIACO E DEL SUO ASSETTO EMISETTORIALE
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