1,720,964 research outputs found
Free radicals and endothelial dysfunction: potential positive effects of TNF-α inhibitors.
No full textBehavior of non-classical soluble HLA class G antigens in human immunodeficiency virus 1-infected patients before and after HAART: comparison with classical soluble HLA-A, -B, -C antigens and potential role in immune-reconstitution.
No full textSoluble HLA-G serum levels in patients with the Acquired Immunodeficiency Syndrome affected by different AIDS-defining conditions before and after anti-retroviral treatment
No full textSoluble HLA-G and HLA-A,-B,-C serum levels in patients with allergic rhinitis
No full textBackground: Allergic rhinitis (AR) is characterized by Th2-polarized immune response. Soluble HLA (sHLA) molecules play an immunomodulatory activity. So far, however, no study investigated them in AR. Objective: The aim of this study was to evaluate sHLA-G and sHLA-A,-B,-C serum levels in AR patients with pollen allergy and in a group of healthy controls. Methods: Forty-nine AR patients were enrolled. A group of healthy nonallergic subjects was considered as control. sHLA-G and sHLA-A,-B,-C serum levels were determined by immunoenzymatic method. The study was conducted during the winter, such as outside the pollen season. Results: Allergic patients had significantly higher levels of both sHLA-G (P < 0.0001) and sHLA-A,-B,-C (P = 0.011) molecules than normal controls. Moreover, there was a significant relationship between these two soluble molecules (r = 0.69) in allergic patients. Conclusion: The present study provides the first evidence that both sHLA-G and sHLA-A,-B,-C serum levels are significantly increased in AR patients with pollen allergy
Recurrent intestinal perforation associated with thrombosis of inferior vena cava: uncommon presentation of antiphospholipid syndrome.
No full textRecurrent intestinal perforation associated with thrombosis of inferior vena cava: uncommon presentation of antiphospholipid syndrome
Nocturia: an uncommon presentation of lower-limb lymphedema.
No full textAn uncommon presentatio of lower limb lymphedema was represented by nocturia. An accurate diagnostic assessment and the treatment of leg lymphedema helped the Authors to solve the clinical dysfunction
Current views on diagnostic approach and treatment of lymphedema
No full textLymphedema is a chronic, progressive, and often debilitating condition. Primary lymphedema is a lymphatic malformation developing during the later stage of lymphangiogenesis. Secondary lymphedema is the result of obstruction or disruption of the lymphatic system, which can occur as a consequence of tumors, surgery, trauma, infection, inflammation, and radiation therapy. In this review, we report an update upon the diagnostic approach and the medical and surgical therapy for both primary and secondary lymphedema
Remission of Brucella endocarditis in a patient with mitral valve mechanical prosthesis by antibiotic therapy alone: a case report
No full textBrucellosis is still a frequently seen major infectious disease, particularly in theMediterranean, the Middle East and Central and South American Countries. Although typical brucellosis is easily diagnosed in endemic areas, in other regions where the incidence of Brucella is very low, definitive diagnosis of the infection is quite difficult.A patient presenting with a heart murmur who has a history of ingestion of unpasteurized milk and exposure to infected animals or animal products should be considered as having cardiac manifestations of brucellosis until proved otherwise. Endocarditis and miocarditis are rare but the most serious complications of brucellosis. In infective endocarditis of brucellosis, Brucella melitensis and Brucella abortus are the most frequently isolated species. Brucella appears to be a slowly destructive organism, with a marked tendency to tissue ulceration, the development of large vegetations carrying a significant risk of embolization and difficulty in eradicating with medical therapy alone. For these reasons, optimal treatment of prosthetic valve Brucella endocarditis (BE) should achieve the sterilization of infected cardiac tissue and extensive surgical debridement without delay to control acute ilness and prevent complications and/or relapse. In the present paper we report the case of prosthetic valve BE that was successfully treated with a multiple bactericidal antibiotics alone
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