487 research outputs found
An Investigation of A Possible Dependence of Brewer Number 67s Total-ozone Measurements On Some Atmospheric Parameters, Together With A Presentation of A Peculiar Synoptic Ozone Case At Rome
No full textBrewer total ozone data (January-December 1992) measured at the Physics Department, Pome University > (41.9 degrees North, 12.5 degrees East) are analysed for dependence on Brewer internal temperature and some meteorological parameters. Non-parametric correlation analysis reveals the independence of total ozone from the internal Brewer temperature. Attention is focused on a peculiar case to show, by means of vertical wind velocity profile, the possible effects of lower stratospheric vertical advection on ozone fluctuations
Heat Wave Changes in the Eastern Mediterranean since 1960
Get PDFA new data set of high-quality homogenized daily maximum and minimum summer air temperature series from 246 stations in the eastern Mediterranean region (including Albania, Bosnia-Herzegovina, Bulgaria, Croatia, Cyprus, Greece, Israel, Romania, Serbia, Slovenia, Turkey) is developed and used to quantify changes in heat wave number, length and intensity between 1960 and 2006. Daily temperature homogeneity analyses suggest that many instrumental measurements in the 1960s are warm-biased, correcting for these biases regionally averaged heat wave trends are up to 8% higher. We find significant changes across the western Balkans, southwestern and western Turkey, and along the southern Black Sea coastline. Since the 1960s, the mean heat wave intensity, heat wave length and heat wave number across the eastern Mediterranean region have increased by a factor of 7.6 +/- 1.3, 7.5 +/- 1.3 and 6.2 +/- 1.1, respectively. These findings suggest that the heat wave increase in this region is higher than previously reported. Citation: Kuglitsch, F. G., A. Toreti, E. Xoplaki, P. M. Della-Marta, C. S. Zerefos, M. Turkes, and J. Luterbacher (2010), Heat wave changes in the eastern Mediterranean since 1960, Geophys. Res. Lett., 37, L04802, doi: 10.1029/2009GL041841.6th EU Framework Programm CIRCE [036961]; 7th EU Framework program ACQWA [212250]; MedClivarWe are grateful to G. van der Schrier and partners from the ECA&D at the KNMI, the Hellenic National Meteorological Service, O. M. Gokturk, and the Turkish State Meteorological Service for providing data. This research was funded by the 6th EU Framework Programm CIRCE (#036961). JL acknowledges support from the 7th EU Framework program ACQWA (#212250) and MedClivar (http://www.medclivar.eu/). The reviewers made useful comments and suggestions and helped to improve the quality of this study
Impact of Thunderstorms on the NOx Budget in the Upper Troposphere over Europe: Observations from Airborne Measurements during LINOX, EULINOX, EXPORT, and CONTRACE
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Analysis of short-lived episodes of low and high ozone amounts recorded during the last decade at Rome Brewer station
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Inter-annual variability of high-latitude stratospheric ozone from satellite observations and model calculations
Get PDFIt has been shown that the inter-annual variability of total ozone in the polar regions of both hemispheres is highly correlated with the flux of planetary waves into the stratosphere. In order to estimate the relative importance of transport and chemistry on the inter-annual variability of high latitude ozone, we use a chemical transport model (CTM) together with observations from the Global Ozone Monitoring Experiment (GOME) and the Total Ozone Mapping Spectrometer (TOMS). We find that the expected inter-annual variability of total ozone in the northern hemisphere in the absence of polar ozone depletion is not significantly different from the observed variability, in contrast to the southern hemisphere, where chemical ozone depletion is the dominant effect. However, the large uncertainty of the planetary wave flux in current meteorological analyses is a limiting factor for modeling the inter-annual variability of total ozone
Gender and neurogenin3 influence the pathogenesis of ketosis-prone diabetes.
No full textKetosis-prone diabetes (KPD) is a phenotypically defined form of diabetes characterized by male predominance and severe insulin deficiency. Neurogenin3 (NGN3) is a proendocrine gene, which is essential for the fate of pancreatic beta cells. Mice lacking ngn3 develop early insulin-deficient diabetes. Thus, we hypothesized that gender and variants in NGN3 could predispose to KPD. We have studied clinical and metabolic parameters according to gender in patients with KPD (n = 152) and common type 2 diabetes (T2DM) (n = 167). We have sequenced NGN3 in KPD patients and screened gene variants in T2DM and controls (n = 232). In KPD, male gender was associated with a more pronounced decrease in beta-cell insulin secretory reserve, assessed by fasting C-peptide [mean (ng/ml) +/- s.d., M: 1.1 +/- 0.6, F: 1.5 +/- 0.9; p = 0.02] and glucagon-stimulated C-peptide [mean (ng/ml) +/- s.d., M: 2.2 +/- 1.1, F: 3.1 +/- 1.7; p = 0.03]. The rare affected females were in an anovulatory state. We found two new variants in the promoter [-3812T/C (af: 2%) and -3642T/C (af: 1%)], two new coding variants [S171T (af: 1%) and A185S (af: 1%)] and the variant already described [S199F (af: 69%)]. These variants were not associated with diabetes. Clinical investigation revealed an association between 199F and hyperglycaemia assessed by glycated haemoglobin [HbA1c (%, +/-s.d.) S199: 12.6 +/- 1.6, S199F: 12.4 +/- 1.4 and 199F: 14.1 +/- 2.2; p = 0.01]. In vitro, the P171T, A185S and S199F variants did not reveal major functional alteration in the activation of NGN3 target genes. In conclusion, male gender, anovulatory state in females and NGN3 variations may influence the pathogenesis of KPD in West Africans. This has therapeutic implications for potential tailored pharmacological intervention in this population
Operational Monitoring of the Antarctic Ozone Hole: Transition from GOME and SCIAMACHY to GOME-2
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