317 research outputs found
FIGURE. Pollen morphology of S. glandulata and S. lupulina observed under SEM. A–C. Strobilanthes lupulina. A: Equatorial view, B, C: Exine ornamentation. D–F. Strobilanthes glandulata. D: Equatorial view, E, F: Exine ornamentation. in Strobilanthes glandulata (Acanthaceae), a new species from Sri Lanka based on the morphological and molecular evidences
No full textFIGURE. Pollen morphology of S. glandulata and S. lupulina observed under SEM. A–C. Strobilanthes lupulina. A: Equatorial view, B, C: Exine ornamentation. D–F. Strobilanthes glandulata. D: Equatorial view, E, F: Exine ornamentation.Published as part of Nilanthi, Rajapakse Mudiyanselage Renuka, Samarakoon, Hiruna, Jayawardana, Nuwan, Hathurusinghe, Bhagya, Wijesundara, Siril & Bandaranayake, Pradeepa Chandani Gunathilake, 2022, Strobilanthes glandulata (Acanthaceae), a new species from Sri Lanka based on the morphological and molecular evidences, pp. 1-14 in Phytotaxa 573 (1) on page 4, DOI: 10.11646/phytotaxa.573.1.1, http://zenodo.org/record/732940
Genomic characterization of multi-parental populations of sorghum and rice
No full textThis thesis describes research work performed at the University of Illinois at Urbana- Champaign (UIUC) and the International Rice Research Institute (IRRI) on genetic analysis of two important cereal crops, sorghum and rice. Research presented in chapters 1 and 2 was performed at UIUC under the supervision of Dr. Patrick J. Brown, and research presented in chapter 3 was performed at IRRI under the supervision of Dr. Kenneth L. McNally.
Sorghum is the world’s fifth most important cereal crop and is critical for food security in semi-arid regions. Chapter 1 describes the generation of genetic linkage maps for eight sorghum recombinant inbred line (RIL) populations using genotyping-by-sequencing (GBS) data. In this work, 1626 RILs from eight biparental populations were genotyped using a modified GBS protocol with Y-adapters. For SNP calling used the TASSEL5 GBS pipeline, and genetic linkage maps were produced using ASMap, an R package that implements MSTMap algorithm. Chapter 2 describes the skim (~5X) sequencing of 240 bioenergy sorghum genomes, using a whole-genome sequencing library preparation protocol that was developed in-house and is cost- effective and less labor-intensive than existing methods.
Rice is a staple food for most of the world’s population, and 90% of the rice produced globally is used for human consumption. Rice production requires a significant amount of fresh water. Drought is one of the major abiotic stresses of rice and is responsible for up to 40% yield loss of total world production, annually. Modern rice cultivars have lost most of their genetic diversity, and the use of crop wild relatives (CWRs) in breeding needs to be explored. IRRI has developed four backcross introgression line (BIL) populations using wild progenitors of Asian cultivated rice as donor parents. Chapter 3 describes the genotype data analysis of these four populations and phenotyping of a subset of each of the four populations under well-watered and managed water stress conditions. This field experiment was conducted at IRRI in the Philippines during the 2018 dry season. Analysis of phenotype data collected for the subsets indicates considerable genotypic variation, and researchers have shown interest in using these lines in their breeding programs. A total of sixteen lines, four from each population, were selected based on the 2018 DS and are being tested at IRRI for physiological traits.Submission published under a 24 month embargo labeled 'U of I Access', the embargo will last until 2021-12-01The student, Pradeepa Hirannaiah, accepted the attached license on 2019-11-05 at 15:40.The student, Pradeepa Hirannaiah, submitted this Dissertation for approval on 2019-11-05 at 15:42.This Dissertation was approved for publication on 2019-11-06 at 15:55.DSpace SAF Submission Ingestion Package generated from Vireo submission #14529 on 2020-02-28 at 17:21:49Made available in DSpace on 2020-03-02T22:12:16Z (GMT). No. of bitstreams: 3
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FIGURE. Strobilanthes glandulata. A in Strobilanthes glandulata (Acanthaceae), a new species from Sri Lanka based on the morphological and molecular evidences
No full textFIGURE. Strobilanthes glandulata. A. Habit; B. Flowering branch; C. Inflorescence; D & F. Leaves adaxial and abaxial view; E. front view of corolla; G. Internode; H. Bracts.Published as part of Nilanthi, Rajapakse Mudiyanselage Renuka, Samarakoon, Hiruna, Jayawardana, Nuwan, Hathurusinghe, Bhagya, Wijesundara, Siril & Bandaranayake, Pradeepa Chandani Gunathilake, 2022, Strobilanthes glandulata (Acanthaceae), a new species from Sri Lanka based on the morphological and molecular evidences, pp. 1-14 in Phytotaxa 573 (1) on page 7, DOI: 10.11646/phytotaxa.573.1.1, http://zenodo.org/record/732940
FIGURE. Strobilanthes glandulata. A in Strobilanthes glandulata (Acanthaceae), a new species from Sri Lanka based on the morphological and molecular evidences
No full textFIGURE. Strobilanthes glandulata. A. Corolla split open showing the stamens; B. Inflorescence; C. Leaf; D. Flowering branch; E. Close up of the leaf surfaces.Published as part of Nilanthi, Rajapakse Mudiyanselage Renuka, Samarakoon, Hiruna, Jayawardana, Nuwan, Hathurusinghe, Bhagya, Wijesundara, Siril & Bandaranayake, Pradeepa Chandani Gunathilake, 2022, Strobilanthes glandulata (Acanthaceae), a new species from Sri Lanka based on the morphological and molecular evidences, pp. 1-14 in Phytotaxa 573 (1) on page 9, DOI: 10.11646/phytotaxa.573.1.1, http://zenodo.org/record/732940
FIGURE. Strobilanthes lupulina. A in Strobilanthes glandulata (Acanthaceae), a new species from Sri Lanka based on the morphological and molecular evidences
No full textFIGURE. Strobilanthes lupulina. A. Flowering branch; B–C Inflorescence; D. Leaves adaxial and abaxial view; E. Bracts; F. Corolla split open showing the stamens; G. front view of corolla; H. Close up of the leaf surface; I. Stamens; J. Internode; K. Capsule.Published as part of Nilanthi, Rajapakse Mudiyanselage Renuka, Samarakoon, Hiruna, Jayawardana, Nuwan, Hathurusinghe, Bhagya, Wijesundara, Siril & Bandaranayake, Pradeepa Chandani Gunathilake, 2022, Strobilanthes glandulata (Acanthaceae), a new species from Sri Lanka based on the morphological and molecular evidences, pp. 1-14 in Phytotaxa 573 (1) on page 8, DOI: 10.11646/phytotaxa.573.1.1, http://zenodo.org/record/732940
FIGURE. Strobilanthes lupulina. A in Strobilanthes glandulata (Acanthaceae), a new species from Sri Lanka based on the morphological and molecular evidences
No full textFIGURE. Strobilanthes lupulina. A. Capsule; B. Calyx; C. Bracts; D. Corolla split open showing the stamens; E. Inflorescences; F. Flowering branch; G. Close up of the leaf surfaces; H. Leaf.Published as part of Nilanthi, Rajapakse Mudiyanselage Renuka, Samarakoon, Hiruna, Jayawardana, Nuwan, Hathurusinghe, Bhagya, Wijesundara, Siril & Bandaranayake, Pradeepa Chandani Gunathilake, 2022, Strobilanthes glandulata (Acanthaceae), a new species from Sri Lanka based on the morphological and molecular evidences, pp. 1-14 in Phytotaxa 573 (1) on page 10, DOI: 10.11646/phytotaxa.573.1.1, http://zenodo.org/record/732940
The Survival Of The National Institute Of Library And Information Sciences In A Turbulent Public University
No full textThe public university system of Sri Lanka faces a number of difficulties. The National Institute of Library and Information Sciences (NILIS) was established affiliated to a university with World Bank aid. However NILIS had to face several problems at the inception and it was almost closed down. The author describes the threats encountered by LIS schools in other countries and the strategies at the macro and micro level, adopted especially by the developed countries, to survive and develop. She further explains different strategies adopted for the survival of NILIS. Expansion in participation with other departments and expansion alone using a variety of innovations take prominence here
The role of MAPKs in CNS demyelination
No full textMAPKs are protein kinases that play crucial roles in regulating cell proliferation, survival and differentiation. In the central nervous system (CNS), p38 MAPK and Erk1/2 play an essential role during development of the oligodendrocyte lineage and are necessary for myelination. However, the effects on mature myelin, particularly under pathological conditions remain unclear. In various neurodegenerative diseases, mature myelin deteriorates, leading to myelin loss and neuronal dysfunction. Several growth factors and cytokines are found to be increased in the demyelinated lesions suggesting that the extracellular stimuli may contribute to the myelin pathology and the subsequent changes in oligodendrocyte phenotypes. In this study, we investigated the effects of growth factor signaling on mature oligodendrocytes and the myelin. Specifically, we investigated the role of Erk1/2 and p38 MAPK activation in triggering oligodendrocyte demyelination. Using an in vitro model for CNS demyelination, we show that growth factors that are found upregulated in CNS lesions, such as FGF-2 promotes myelin breakdown through activation of the Erk1/2 and p38 MAPK pathways. We also show that ectopic activation of either Erk1/2 or p38 MAPK is sufficient to induce demyelination. Our study also indicates that growth factor or MAPK-induced demyelination was not associated with cell death, indicating the possibility of oligodendrocyte de-differentiation. To further investigate this, in chapter three we characterized the phenotype of mature oligodendrocytes following MAPK activation. Ectopic activation of Erk1/2 in mature oligodendrocytes resulted in the down-regulation of myelin proteins and a drastic change in cell morphology. A similar phenotypic change was also observed upon ectopic activation of p38 MAPK. Interestingly, after inducing the phenotypic changes, Erk1/2 activation but not p38 MAPK was sufficient to direct non-proliferating mature oligodendrocytes to re-enter the cell cycle. This result suggests that mature oligodendrocytes may have the ability to regenerate and remyelinate following the myelin loss. These studies also demonstrate that MAPKs are crucial in regulating this process. In chapter four, we investigated whether Erk1/2 mediates oligodendrocyte demyelination induced under pathological conditions. To this end, we used an in vitro model for white matter injury in which diffused axon injury is mimicked by mechanical stretching of the myelinated axons in culture. Our data shows that axonal stretch injury induces oligodendrocyte demyelination independent of axon degeneration and inhibition of Erk1/2 activation has a protective effect on the myelin. Altogether, these results suggest that MAPKs play an essential role in triggering oligodendrocyte demyelination and promoting phenotypic changes that may contribute to the subsequent regenerative process of remyelination.Ph. D.Includes bibliographical referencesIncludes vitaby Pradeepa Gokin
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Library and information science education in South Asia: Challenges and opportunities
No full textAll is not good with Library and Information Science (LIS) Education in South Asia. Out of the seven countries in South Asia; India, Pakistan, Sri Lanka, and Bangladesh have provision for Library and Information Science Education, whereas Nepal, Bhutan, and the Maldives depend upon outside support for educating and training people for looking after their professional turf. Existing body of literature shows that in India there is a mushroom growth of Library and Information Science Departments. There is no professional accreditation, though institutional accreditation is in place in India. Many departments have failed to respond adequately to the ICT-based developments. Nomenclature of the courses offered has changed but the course contents are not consistent with the nomenclature in many cases. Moreover, these departments are seriously suffering from insufficient infrastructure, inadequate faculty, lack of quality research and document support. The course contents are not informed by the emerging employment opportunities in the corporate sector. Even today, the focus is on technical services. Academic Librarianship and Literature survey in social sciences are the only options offered by majority of LIS Programmes in India. Whereas, the core is still stuck to classification, cataloguing, indexing, and vocabulary control, the emerging themes, such as information literacy, knowledge management, elearning, ICT application, use of networks in teaching, and teaching about networks have not been adequately integrated in the curricula. On the top of it, there is limited Internet connectivity available in these departments. Attitude of authorities is also not that encouraging as these departments, being small, are considered liabilities. Above all, these departments have not, till today, internalized the concept and practice of cooperation and collaboration. Globalization and privatization of LIS education under GATS is another threat to the developing countries as it will lead to competition among the unequal. In fact, LIS education in majority of the departments in South Asia is in shambles
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