124 research outputs found
Chronic Interstitial lung disease in children
No full textChronic interstitial lung disease (ILD) is rare in children, but is clinically relevant because of its high morbidity and mortality rates. Several aetiological agents may have a role in this disease and various aetiopathogenic forms have been described, although they share a characteristic evolution towards pulmonary fibrosis. The aetiology sometimes remains unknown, in which case we speak of idiopathic interstitial pneumonia (IIP). Diagnosis relies on non-invasive methods (clinical history, respiratory function tests, chest X-ray and high-resolution CT scan) and invasive techniques (bronchoalveolar lavage, transbronchial biopsy, video-assisted thoracoscopic biopsy and open lung biopsy); the latter are used when the former fail to identify an aetiological agent. The gold standard for the diagnosis is lung biopsy, however, which also enables the classification of the idiopathic forms, in particular (usual interstitial pneumonia, desquamative interstitial pneumonia, non-specific interstitial pneumonia, and so on). In ILD, the most common therapeutic approaches involve the use of oral steroids and hydroxychloroquine sulphate for its anti-inflammatory and antifibrotic effect. The prognosis is often poor
L'asma nel bambino: dalla diagnosi alla terapia
No full textGli autori descrivono i vari steps diagnostici dell'asma bronchiale infantile e la terapia finora disponibile, basata sull'uso di farmaci differenti a seconda della gravità della malattia e della presenza o meno di accessualità
Lo stridore laringeo:inquadramento nosologico ed iter diagnostico
No full textNel lavoro vengono riportati alcuni casi clinici di stridore laringeo in lattanti e ne vengono descritte le possibili etiologie, le possibilità diagnostiche e terapeutiche
Asma in età pediatrica: le dimensioni socio-economiche del problema
No full textNel lavoro viene fatta una revisione della letteratura sulle dimensioni socioeconomiche dell'asma, considerando i costi diretti e indiretti sulla famiglia e la Società
Case 4: presentation Interstitial lung disease. In a child with systemic lupus erythematotus
No full textThe AA. describe the presence of ILD in a child with LES,as manifestation of autoimmune disease
Supplier Involvement in Integrated Product Development: Evidence from a group of Italian SMEs
No full textIntegrated product development (IPD) is gaining increased attention from practitioners and the academic community as a source of innovation and competitive advantage. However undeniable the importance of the issue is as to how the different actors involved in the process interact among themselves and the supporting factors not being well understood even in the SME context, the availability of empirical research and a comprehensive framework to drive this research remains unavailable. This article contributes to these research gaps by providing theoretical and empirical findings. First, a research framework on IPD is identified. The proposed framework represents a conceptualisation of IPD principles as consisting of three groups of integration enablers, which aim to achieve high internal (among departments) and external (with suppliers and customers) integration: (a) organisational enablers, (b) technological enablers and (c) methodologies. Then, a multiple case study approach is used in order to empirically explore external integration with suppliers in product development in 22 SMEs from the machine tool sector
Construction and test of a GRIN based optical objective.
No full textOptical fibres with their unique ability to transport light even in a coherent way (fibre bundles) and the possibility to build small volume optical pieces (Graded Index Fibres, GRIN) have a dominant role in the assembly of probes and objectives for microscopy applications requiring noninvasive and flexible operation in small and crowded spaces (in vivo microscopy, endoscopy, inspection). Nowadays, even complex observing procedures like confocal, two-photon and optical coherence tomography can be approached with fibres, making possible in vivo applications and also in place decision and processing. We present here a series of analytical simulations and practical tests made on an experimental GRIN fibre objective light fed through an adaptive optics system aimed to verify the practical possibility to correct a focalized beam of light. We intend this as a first step to the implementation of non-invasive probes making use of forthcoming optical devices (scanners, deformable mirrors) based on MEMS technology
An unusual cause of pneumonia in a child. Eur. Respir. J. 2005; 26 (49): 630s.
No full textA case of rare pneumonia in children is described by the author
Chronic cough and neutrophilic BAL in children.
No full textThe authors describe the BAL neutrophilia found in children with chronic cough
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