1,721,026 research outputs found

    “Substrato bioartificiale per la realizzazione di tessuti e organi animali, in particolare umani”

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    A bioartificial substrate made up by the silk fibroin (Bombyx mori), an insect protein, is patented in view of its possible use for the regeneration of human tissues and organs

    Laminates of poly(2-hydroxyethyl methacrylate) and polybutadiene as potential burn covering

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    The preparation and the physical characterization of poly (2-hydroxyethyl methacrylate) thermally grafted onto polybutadiene (PHEMA/PB) are reported. The presence of polybutadiene increases the tensile properties of the film an prevents water diffusion through it while it does not affect the oxygen permeability of the PHEMA. The potential use of this material as burn wound cover is suggested

    Silk protein-based scaffolds for bone tissue engineering : an in vivo study

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    Silk fibroin (SF) is the inner component of the silk fiber spun by Bombyx mori silkworm. It is considered a valuable material for biotechnology and biomedical applications due to its unique properties including biocompatibility, oxygen and water vapor permeability, biodegradability, and minimal inflammatory reaction. Sericin, which constitutes the outer layer of the fiber, was recently studied by several authors who underlined its antioxidant, antibacterial and anti-inflammatory properties, its protective action for serum deprived cells, being moreover considered a triggering molecule for apatite deposition. Fibroin and sericin can be processed to obtain powders, films, gels, filaments, etc., so making different materials that can tailored to the requirements of the specific application. These processes induce structural transitions and morphological changes that have a great influence on the physical and biological properties of the resulting materials. In this work two different SF-based hydrogels (100% SF and 90/10SF-Ser) and a pure fibroin sponge were compared in an in vivo critical size defect study in order to evaluate their bone regeneration capability

    Luminescent graphene quantum dots from oxidized multi-walled carbon nanotubes

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    Fluorescent nano-graphene quantum dots (GQD) were isolated from oxidized carbon nanotube suspension with the aid of cysteamine. The oxidized GQD were thiol functionalized with cysteamine in presence of dicyclohexylcarbodiimide as coupling agent. The GQD chemistry and morphology were characterized by means of X-ray photoelectron spectroscopy and atomic force microscopy. The thiolated graphene quantum dots exhibit an intense luminescence (quantum yield around 10%) in the visible range with an excitation wavelength-dependent fluorescence
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