217 research outputs found
The structure and characteristics of the Nimonic 80° superalloy obtained through the specifical procedures of the powder metallurgy
No full text13 INVENTIONS FOR PIANO BY I. MACOVEI: TRADITIONALISM AND NOVELTY IN ORGANIZING THE POLYPHONY CYCLE
No full textThis article contains an analysis of a cycle of 13 inventions for piano by I. Macovei in view of carrying on I.S. Bach′s traditions and as a composition of the second half of the 20th century created in the tradition of Moldovan folklorism and influenced by B. Bartók′s style. The author examines a wide spectrum of polyphony devices and their role in the composition of the whole cycle
The TFIIS and TFIIS-like genes from Medicago truncatula are involved in oxidative stress response
No full textThe cDNA sequence coding for a novel putative TFIIS (transcription elongation factor II-S), hereby named MtTFIIS-like, was isolated from barrel medic (Medicago truncatula Gaertn.) by reverse transcriptase-polymerase chain reaction. The nucleotide sequence contains an open reading frame of 1074 bp, predicting a 40.0 kDa protein, conserved among plant species. The N-terminal region of the MtTFIIS-like protein includes a LW motif, characterized by highly conserved leucine (L) and tryptophan (W) residues, also found in the canonical TFIIS protein, elongin A (transcription elongation factor S-III) and CRSP70 (cofactor required for Sp1 activation), while a proline-rich region is present in the C-terminal domain. The expression profiles of the MtTFIIS-like gene were evaluated by quantitative real-time PCR (QRT-PCR) in barrel medic plantlets grown in vitro under oxidative stress conditions induced by copper (CuCl2 0.05, 0.1 and 0.2 mM) and polyethylene glycol (PEG6000 50, 100 and 150 g/L), respectively. Both stress agents caused ROS (reactive oxygen species) accumulation. Moreover, EPR spectra of leaves from plantlets exposed to toxic copper doses confirmed that the heavy metal is translocated from roots to the aerial parts, where it is found predominantly in the Cu2+ redox state. The MtTFIIS-like gene expression was significantly enhanced (up to 2.9-fold) in aerial parts of copper-treated plants, and in roots (up to 4.4-fold) in response to PEG treatments. The expression profiles of the MtTFIIS-like gene were compared to those of the MtTFIIS gene, encoding the canonical TFIIS protein, which was similarly up-regulated in response to both stresses. Interestingly, the MtTFIIS-like and MtTFIIS genes were significantly up-regulated (up to 3.2- and 4.3-fold, respectively) during seed imbibition, a physiological process which requires active DNA repair. Based on the reported data, the possible roles played in planta by the novel MtTFIIS-like gene are discussed
Nitric oxide biosynthesis in white poplar (Populus alba L.) suspension cultures challenged with heavy metals
No full textVersatile multiview layered video based on distributed source coding
No full textVideo content constitutes today a large part of the data traffic on the Internet. This is allowed by the capillary spreading of video codec technologies: nowadays, every computer, tablet and smart phone is equipped with video encoding and decoding technologies. As a matter of fact, the video content often exists in different formats, that, even though they can be incompatible to each other, still have a significant mutual redun-dancy. The incompatibility prevents an efficient exploitation of the scalability, which on the other hand is a very important characteristic when it comes to efficient network use. An interesting alternative to classical scalable video is to use distributed video coding (DVC) for the enhancement layers. In the envisaged scenario, clients have different decoders for the base layer, adapted to the characteristics of their de-vice. However they can share the same enhancement layer, since DVC allows encoding frames independently from the reference that will be employed at the decoder. This approach has been considered in the past in order to improve temporal and spatial scalability. In this work we review the existing approaches, improve them using more recent DVC techniques and perform a new analysis for the emerging multi-view applications. © 2013 IEEE
CdSe/ZnS Quantum Dots trigger DNA repair and antioxidant enzyme systems in Medicago sativa cells in suspension culture
No full textSeed-specific expression of AINTEGUMENTA in Medicago truncatula led to the production of larger seeds and improved seed germination.
No full textPeritoneal carcinomatosis from unusual cancer origins: Is there a role for hyperthermic intraperitoneal chemotherapy?
No full textComplete cytoreductive surgery (CCRS) plus hyperthermic intraperitoneal chemotherapy (HIPEC) is the gold standard for curative treatment of peritoneal carcinomatosis (PC) arising from colorectal cancer, peritoneal mesothelioma and peritoneal pseudomyxoma peritonei (PMP). The results of HIPEC remain controversial in PC that originates from ovarian cancer, stomach cancer, neuroendocrine tumors, or sarcoma. HIPEC has also been used, although very rarely, for other malignant carcinomatoses. Its use has been exceptional due either to the rarity of the tumor or because such disease is usually widespread and rarely confined to the peritoneum. The aim of this study was to evaluate the results of CCRS plus HIPEC in patients with PC of unusual origin
A Bioinformatics Approach to Explore MicroRNAs as Tools to Bridge Pathways Between Plants and Animals. Is DNA Damage Response (DDR) a Potential Target Process?
No full textMicroRNAs, highly-conserved small RNAs, act as key regulators of many biological functions in both plants and animals by post-transcriptionally regulating gene expression through interactions with their target mRNAs. The microRNA research is a dynamic field, in which new and unconventional aspects are emerging alongside well-established roles in development and stress adaptation. A recent hypothesis states that miRNAs can be transferred from one species to another and potentially target genes across distant species. Here, we propose to look into the trans-kingdom potential of miRNAs as a tool to bridge conserved pathways between plant and human cells. To this aim, a novel multi-faceted bioinformatic analysis pipeline was developed, enabling the investigation of common biological processes and genes targeted in plant and human transcriptome by a set of publicly available Medicago truncatula miRNAs. Multiple datasets, including miRNA, gene, transcript and protein sequences, expression profiles and genetic interactions, were used. Three different strategies were employed, namely a network-based pipeline, an alignment-based pipeline, and a M. truncatula network reconstruction approach, to study functional modules and to evaluate gene/protein similarities among miRNA targets. The results were compared in order to find common features, e.g., microRNAs targeting similar processes. Biological processes like exocytosis and response to viruses were common denominators in the investigated species. Since the involvement of miRNAs in the regulation of DNA damage response (DDR)-associated pathways is barely explored, especially in the plant kingdom, a special attention is given to this aspect. Hereby, miRNAs predicted to target genes involved in DNA repair, recombination and replication, chromatin remodeling, cell cycle and cell death were identified in both plants and humans, paving the way for future interdisciplinary advancements
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