36,937 research outputs found
Linear representations of circular plasmids observed in USA300-HOU-MR (a, b) and USA300-MS (c)
No full text<p><b>Copyright information:</b></p><p>Taken from "Subtle genetic changes enhance virulence of methicillin resistant and sensitive "</p><p>http://www.biomedcentral.com/1471-2180/7/99</p><p>BMC Microbiology 2007;7():99-99.</p><p>Published online 6 Nov 2007</p><p>PMCID:PMC2222628.</p><p></p> Replication and regulatory genes are colored red, recombination/transposition genes are green, antibiotic/heavy metal/bacteriocin resistance genes are blue, other genes are white and hypothetical, conserved hypothetical (CHP) and staphylococcal conserved hypotheticals (SCHP) are colored grey. Horizontal bars indicate the regions of pUSA300-HOU-MR and pUSA300-HOU-MS having homology with other sequenced staphylococcal plasmids
MPTP/MPP+ suppresses activation of protein C in Parkinson's disease
No full textEndothelial dysfunction and disruption of the blood-brain barrier have been found to be associated with Parkinson's disease (PD). However, the mechanisms underlying these effects have yet to be elucidated. It has also been found that activated protein C (APC) displays neuroprotective properties. Presently, the effects of APC on PD remain unknown. Using a 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP) neurotoxin rodent model of PD, we found that administration of MPTP can reduce expression of endothelial protein C receptor (EPCR), an N-glycosylated type I membrane protein that has the ability to enhance protein C activation. However, the use of MPTP does not alter levels of thrombomodulin. These findings were verified in an in vitro study showing that 1-methyl-4-phenylpyridinium (MPP+) treatment leads to suppression of EPCR along with reduction of protein C activation in human primary endothelial cells. Importantly, our results display that activation of the transcriptional factor SP1 is involved in the inhibitory effects of MPTP/MPP+ on EPCR expression. We found that using 300 nM of the SP1 inhibitor MIT can abolish the effects of MPP+ on EPCR expression. Consistently, SP1 silencing using small RNA interference was able to prevent the inhibitory effects of MPTP/MPP+ on the reduction of EPCR expression and impairment of protein C activation. Importantly, our results indicate that overexpression of SP1 inhibits EPCR promoter activity. Our study suggests that EPCR-APC may be a potential therapeutic target for endothelial dysfunction in P
Cong Han Ming liang chao de Taishan chong bai zhi bi jiao kan sheng shan zai Zhongguo zong jiao zhi yi yi.
No full text侯淑美.論文(哲學碩士) -- 香港中文大學硏究院宗敎及神學學部, 1996.參考文献 : leaves ii-vii (2nd group).Hou Shumei.Chapter 第一章 --- 導言 --- p.1 一6Chapter 第二章 --- 背景資料 --- p.7 ´ؤ19Chapter 第一節 --- 泰山之名Chapter 第二節 --- 五嶽之名之源由演變Chapter 第三節 --- 漢朝以前的人對山嶽的理解Chapter 第三章 --- 漢朝的泰山崇拜 --- p.20 ´ؤ52Chapter 第一節 --- 統治者的泰山崇拜Chapter (A) --- 引言Chapter (B ) --- 封禪Chapter (一） --- 封禪之簡介及解釋Chapter (二） --- 封禪的必備條件Chapter (三） --- 漢武帝封禪Chapter (四） --- 光武帝封禪Chapter (C --- ) 祭泰山Chapter (D --- ) 小結Chapter 第二節 --- 民間信仰者的泰山崇拜Chapter (A ) --- 引言Chapter (B ) --- 魂歸泰山的思想Chapter (一） --- 泰山是人死後的住所Chapter (二） --- 在泰山的死後世界中的官僚組織Chapter (三） --- 在泰山死後世界的生活Chapter (C ) --- 小結Chapter 第四章 --- 明朝的泰山崇拜 --- p.53 ´ؤ82Chapter 第一節 --- 統治者的泰山崇拜Chapter (A ) --- 引言Chapter (B ) --- 祭泰山Chapter (一) --- 祭泰山的內容Chapter (二） --- 在統治者的心目中，泰山之神之職能Chapter (C ) --- 小結Chapter 第二節 --- 民間信仰者的泰山崇拜Chapter (A ) --- 引言Chapter (B ) --- 朝泰山進香的情況Chapter (C ) --- 碧霞元君信仰Chapter (一) --- 碧霞元君的來歷之傳說Chapter (二） --- 碧霞元君的職能Chapter (D ) --- 小結Chapter 第五章 --- 漢朝與明朝的泰山崇拜 之比較 --- p.83 ´ؤ97Chapter 第六章 --- 總結 --- p.98 ´ؤ101縮寫說明 --- p.i書目 --- p.i i 一 vi iChapter (一） --- 工具書Chapter (二） --- 道藏內文獻及中國古籍Chapter (三） --- 其他書籍及期
Enantioselective palladaelectro-catalyzed C–H olefinations and allylations for N–C axial chirality
No full textEnantioselective palladaelectro-catalyzed C–H alkenylations and allylations were achieved by the means of an easily-accessible amino acid for the synthesis of N–C axially chiral indole biaryls.Enantioselective palladaelectro-catalyzed C–H alkenylations and allylations were achieved with easily-accessible amino acids as transient directing groups. This strategy provided access to highly enantiomerically-enriched N–C axially chiral scaffolds under exceedingly mild conditions. The synthetic utility of our strategy was demonstrated by a variety of alkenes, while the versatility of our approach was reflected by atroposelective C–H allylations. Computational studies provided insights into a facile C–H activation by a seven-membered palladacycle.Enantioselective palladaelectro-catalyzed C–H alkenylations and allylations were achieved by the means of an easily-accessible amino acid for the synthesis of N–C axially chiral indole biaryls.Enantioselective palladaelectro-catalyzed C–H alkenylations and allylations were achieved with easily-accessible amino acids as transient directing groups. This strategy provided access to highly enantiomerically-enriched N–C axially chiral scaffolds under exceedingly mild conditions. The synthetic utility of our strategy was demonstrated by a variety of alkenes, while the versatility of our approach was reflected by atroposelective C–H allylations. Computational studies provided insights into a facile C–H activation by a seven-membered palladacycle
Figure 6 from: Hou Z, Zhao S (2017) A new terrestrial talitrid genus, Myanmarorchestia, with two new species from Myanmar (Crustacea, Amphipoda, Talitridae). ZooKeys 705: 15-39. https://doi.org/10.3897/zookeys.705.15045
No full textFigure 6 -
Myanmarorchestia peterjaegeri Hou, sp. n., male paratype. A gnathopod I B dactylus of gnathopod I C gnathopod II D propodus of gnathopod II E pereopod III F pereopod IV G pereopod V H pereopod VI I pereopod VII
Figure 8 from: Hou Z, Zhao S (2017) A new terrestrial talitrid genus, Myanmarorchestia, with two new species from Myanmar (Crustacea, Amphipoda, Talitridae). ZooKeys 705: 15-39. https://doi.org/10.3897/zookeys.705.15045
No full textFigure 8 -
Myanmarorchestia seabri Hou, sp. n., male holotype. A gnathopod I B dactylus of gnathopod I C gnathopod II D propodus of gnathopod II E propodus of gnathopod II (dorsal view) F coxal gill of gnathopod II
Neoascochyta mortariensis L. W. Hou
No full text<p> <i>Neoascochyta mortariensis</i> L. W. Hou et al., Studies in Mycology. 96: 391. 2020</p> <p>Description.</p> <p>see Hou et al. (2020 b).</p> <p>Materials examined.</p> <p> China, Zhejiang Province, Hangzhou City, from healthy leaves of <i>C. sinensis</i> cv. <i>Longjing 43</i>, 16 Nov. 2017 Y. C. Wang, culture ex-type CGMCC 3.24251 = YCW 1346.</p> <p>Notes.</p> <p> <i>Neoascochyta mortariensis</i> was introduced as <i>Didymella graminicola</i> previously. It was described as a new species in <i>Neoascochyta</i>, distant from the authentic culture of <i>D. graminicola</i> (currently: <i>Neoascochyta graminicola</i>) (Hou et al. 2020 b). <i>Neoascochyta mortariensis</i> was first isolated from <i>Oryza sativa</i> in Italy and formed colonies on PDA covered by dense felty aerial mycelium (Hou et al. 2020 b). It formed a distinct lineage closely related to <i>N. tardicrescens</i> (Fig. 4). In the present study, one strain was isolated from diseased tea plant leaves. This is the first report of <i>N. mortariensis</i> isolated from <i>C. sinensis</i>.</p>Published as part of <i>Wang, Yuchun, Tu, Yiyi, Chen, Xueling, Jiang, Hong, Ren, Hengze, Lu, Qinhua, Wei, Chaoling & Lv, Wuyun, 2024, Didymellaceae species associated with tea plant (Camellia sinensis) in China, pp. 217-251 in MycoKeys 105</i> on pages 217-251, DOI: 10.3897/mycokeys.105.11953
Figure 7 from: Hou Z, Zhao S (2017) A new terrestrial talitrid genus, Myanmarorchestia, with two new species from Myanmar (Crustacea, Amphipoda, Talitridae). ZooKeys 705: 15-39. https://doi.org/10.3897/zookeys.705.15045
No full textFigure 7 -
Myanmarorchestia seabri Hou, sp. n., male holotype. A head B antenna I C antenna II D upper lip E lower lip F left mandible G incisor of right mandible H left maxilla I I maxilla II J maxilliped K outer plate and palp of left maxilliped
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