162 research outputs found
Bonomo Faita e l'opera come ossimoro
No full textBreve intervento sull'opera dell'artista contemporaneo Bonomo Fait
A Robust Design for Cellular Vehicles of Gold Nanorods for Multimodal Imaging
No full textAuthors Dr. Marisa Benagiano and Prof. Mario Milco D’Elios were not included when this article was originally published. The corrected list of author of this manuscript is: F. Ratto,* S. Centi, C. Avigo, C. Borri, F. Tatini, L. Cavigli, C. Kusmic, B. Lelli, S. Lai, M. Benagiano, M. M. D’Elios, S. Colagrande, F. Faita, L. Menichetti, and R. Pini The affiliation for Dr. Benagiano and Prof. D’Elios is: Department of Experimental and Clinical Medicine University of Florence, Largo Brambilla 3, 50134 Florence, (FI), Italy Ref. [82] was not included in the originally published version of this article. It should be added to the second paragraph on page 7179, which then reads as follows: “More recently, the notion to exploit the natural tropism of cells, such as tumor-associated macrophages,[35–39] T cells,[40,82] mesenchymal stem cells,[41–43] and neural stem cells,[44,45] has begun to emerge as a radical alternative.” Ref. [82] is: G. Baldi, C. Ravagli, M. Comes Franchini, M. M. D’Elios, M. Benagiano, M. Bitossi (Colorobbia Italia S.p.A.) WO 104664, 2015. The Acknowledgements should be corrected to read as follows: “This work was in part supported by the Projects of Tuscan Region “NANOTREAT” and “SYNERGY” and by the ERANET+ Project of Tuscan Region and European Community “LUS BUBBLE”. The authors wish to thank Dr. Daniele Panetta for his expertise in X-ray micro imaging and Dr. Giovanni Baldi of CERICOL Research Center of Colorobbia Group for his expertise and knowledge on cellular nano-engineering.” The authors apologize for any inconvenience or misunderstanding that these errors may have caused. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinhei
The anodic dissolution of nickel and molybdenum in methanol and water-methanol mixtures
No full textSome experimental results concerning the anodic behaviour of Nickel and Molybdenum in methanol and water-methanol mixtures are reported. The protective oxide of Ni is destabilized, even in neutral solutions, by the presence of small quantities of chlorides (ca. 3.5-170 ppm). In the case of Mo, the influence of acidity, water content and chloride concentration is negligible, at least in the intermediate region of anodic potentials which is the most interesting for practical applications. © 1980
Transition Metal Promoted Cascade Heterocycle Synthesis through C−H Functionalization
No full textSequential, domino and tandem reactions could be defined as a sequence of synthetic transformations that occur one after the other, in the same reaction flask. This Review highlights recent advances at the overlap of two worlds: transition-metal mediated C−H activation as a trigger of cascade reaction, for the heterocycles synthesis. To shed some light on this intricate “middle-earth”, focus was put on the reaction mechanism rather than the type of metal or the chronological order of the reaction. The aim is to separate, and then highlight, the true domino reactions initiated by C−H activation, compared to other examples of C−H functionalization for heterocycle syntheses
Enantioselectively-Catalyzed Reactions with (E)‐2-Alkenoyl-pyridines, Their N‐Oxides, and the Corresponding Chalcones
No full text1. Introduction
2. Michael Reaction
2.1. Phospha- and Aza-Michael Reactions
2.2. Henry Reaction
2.3. Friedel−Crafts Reaction
3. Epoxidation Reaction
4. Radical Reaction
5. [3 + 2] Dipolar Cycloaddition Reaction
6. D.A. Reaction
6.1. Families of Unusual Catalysts for the D.A.
Reaction
6.1.a. Natural and Artificial Metalloenzymes
6.1.b. DNA-Based Asymmetric D.A. Reaction
7. Hetero D.A. Reaction
8. Influence of Substituents on Reactivity and
Selectivity
9. Relationship between Different Organocatalysts
or Chiral Complexes and the Stereochemical
Outcome
10. Comparison between the Enantioselectively-
Catalyzed Reactions with (E)-2-Alkenoyl-pyridines,
Their N-Oxides, and the Corresponding
Chalcones
11. Conclusions
Associated Content
Supporting Information
Author Information
Corresponding Author
Notes
Biographies
Acknowledgments
Dedication
Reference
Effect of water content on the corrosion behaviour of Ni in methanol (MeOH) solutions
No full textThe effect of water content on the corrosion behaviour of nickel in methanolic solutions have been investigated tracing the potentiostatic curves at room temperature in a standard electrochemical cell. Preliminary results reported in this communication, shown that the electrochemical behaviour of Ni in MeOH is strongly influenced by the water content of the solution and that traces of water (of the order of 0.5%) are able to guarantee the passivity of nickel. © 1981
C2-Symmetric Chiral Bis(Oxazoline) Ligands in Asymmetric Catalysis
No full textA complete and up-to-date review of the bis(oxazolines) as C-2 symmetric chiral ligands in asymmetric synthesis is reported. The review describes the syntheses of more than 150 ligands, their metal-complexes with several cations acting as Lewis acids, and the synthetic applications in more than ten different kind of reactions. The review summarised the results reported in 381 papers
The passivity of ferritic (Fe-18% Cr) stainless steel in methanolic solutions
No full textAn experimental study to define the active-passive behaviour of a ferritic (Fe-18%Cr) stainless steel in methanol, as a function of the concentration of Cl- ions and acidity level, is reported. The addition of water was considered to be an inhibitor capable of reinforcing the passive film of stainless steel. The effects of acidity and of the addition of water on the anodic and cathodic behaviour of Ni, Mo, Fe and The Fe-18%Cr alloy are reported. © 1981 Chapman and Hall Ltd
Non-Invasive Diagnostic Tools for Investigating Endothelial Dysfunction
No full textThe endothelium is not merely a barrier but it plays a key role in the maintenance of vascular homeostasis. A dysfunctional endothelium is an early marker of the development of atherosclerotic changes and can also contribute to cardiovascular events. Vascular reactivity tests represent the most widely used methods in the clinical assessment of endothelial function and in the last two decades, several methodologies were developed to study it non invasively in the peripheral macrocirculation (conduit arteries) and microcirculation (resistance arteries and arterioles). This review will centre on the most relevant available non-invasive techniques in the research on endothelial function, their advantages and limitations. Flow mediated dilation (FMD) of the brachial artery by ultrasounds is the most widely used vascular test to assess endothelium-dependent vasodilation. Other approaches include measurement of microcirculatory reactive hyperaemia by forearm venous pletysmography or digital pulse amplitude tonometry, response to β2 agonist by applanation tonometry or digital photoplethysmography and several test by skin laser doppler. It appears that FMD is the most reproducible test when an appropriate and accurate methodology is applied. Recently, post-ischemic vasodilation in the cavernous arteries was also suggested to study endothelial function in patients with erectile dysfunction. Systemic markers proposed as measures of NO biology, inflammatory cytokines, adhesion molecules, or markers of endothelial damage and repair have only a very limited role as a result of biological and assay availability and variability, these factors currently have a limited role in the assessment of individual patients. The optimal methodology for investigating the multifaceted aspects of endothelial dysfunction is still under debate. Therefore, no available test to assess endothelial function has sufficient sensitivity and specificity to be used yet in clinical practice. Only the growing concordant results from different reproducible and reliable non-invasive methods exploring endothelial function with different stimuli will support and strengthen experimental findings, thus providing conclusive answers in this area of research
The crystal structure of 2-(5,7-dichloro-1-methyloxoindol)-3-spiro-1′(2′-benzoylhexahydropyrrolizin)-3′-spiro-2′′-indian-1′′,3′′-dione
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