396 research outputs found

    predittori di degenza postoperatoria in terapia intensiva post cardiaca

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    predittori di degenza postoperatoria in terapia intensiva post cardiac

    Exercise training counteracts the abnormal release of plasma endothelin-1 in normal subjects at risk of hypertension

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    BACKGROUND: The hypothesis that in normotensive offspring of hypertensive parents exercise training could influence the systemic release of endothelin (ET)-1 during a provocative testing protocol was tested. METHODS: The provocative handgrip test was performed in four groups of healthy young age-matched males: offspring of hypertensive parents following a regular swimming exercise regimen (group A, n = 14); offspring of hypertensive parents and leading a sedentary lifestyle (group B, n = 11); normal volunteers with no family history of hypertension: sedentary (group C, n = 10), and following a regular swimming regimen (group D, n = 10). The plasma ET-1 was measured at baseline, after 4 min of handgrip exercise at 50% maximal capacity and following 2 (R2) and 10 (R10) min of recovery from handgrip. RESULTS: ET-1 plasma levels, within the normal range in all groups at baseline (group A 0.94 +/- 0.32 pg/ml, group B 0.84 +/- 0.26 pg/ml, group C 0.78 +/- 0.35 pg/ml, group D 0.85 +/- 0.26, p = NS) showed a progressive and significant increase in group B during and after handgrip exercise (peak handgrip 1.08 +/- 0.5 pg/ml, p = NS; R2 1.35 +/- 0.36 pg/ml, p < 0.05; R10 2.76 +/- 0.75 pg/ml, p < 0.01). Significant differences were found at R2 and R10 when the ET-1 levels measured in group B were compared to those observed in group A, group C and group D. Multivariate analysis demonstrated that the serum levels of ET-1 significantly contributed to predict handgrip-induced changes when the diastolic blood pressure was the dependent variable. CONCLUSIONS: Routine aerobic exercise appeared to counteract the handgrip-induced abnormal release of plasma ET-1 and may favorably affect the preclinical endothelial alterations seen in healthy offspring of hypertensive parents

    A fuzzy logic technique for virtual sensor networks

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    A virtual sensor network is designed to infer an approximation of real data when the physical sensor network cannot provide it, due to technical or economic reasons. In this paper, we propose an approach to model virtual sensor networks based on fuzzy logic. It relies on the hypothesis that the readings of the physical sensors are correlated. In particular, the virtual sensor network is able to learn the relationships between the physical quantities detected by the sensors and model them through fuzzy rules, which provide an approximation of the real values. In the proposed model, a set of fuzzy rules is derived for each physical sensor. It will provide an accurate approximation of the sensor readings when needed (e.g. sensor malfunction). The proposed approach has been designed as an extension of the well known Tree Routing protocol, used in sensor networks for transmitting sensed data to the base station. It has been implemented in Snlog, a language derived from Datalog that supports the development of distributed algorithms for Wireless Sensor Networks in a declarative way. The experimental evaluation reported in the paper shows the effectiveness and efficacy of our solutions

    On the Role of Morphology of CoFeO4 Spinel in Methanol Anaerobic Oxidation

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    A CoFe2O4 inverse spinel calcined at two different temperatures (450 and 750 °C), in order to modulate the growth of the crystallites, has been employed in methanol anaerobic oxidation. A correlation between physicochemical properties and catalytic performances of the material has been pursued. The study of both surface and bulk properties has been carried out by means of different experimental techniques, among which are X-ray diffraction (XRD), transmission electron microscopy (TEM), and in situ FTIR spectroscopy. The FTIR study of both bulk and surface spectral features reveals that the calcination step is responsible for the different type of exposed surface sites and as a consequence for the different catalytic behavior. As the use of the spinel as the catalyst for methanol transformation into H2 necessarily implies a regeneration step with steam, in order to recover the oxidative capacity of the solid, both surface and bulk features of the reoxidized solids have been also studied. All results reveal that the two samples, originally morphologically quite different from one another, become very similar after just one redox cycle. Still, it has been also demonstrated that both used materials irreversibly modify their surface properties after the reduction/oxidation process

    Coronary rotational atherectomy via transradial approach: A study using radial artery intravascular ultrasound

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    The use of coronary rotational atherectomy via radial artery (RA) has been limited because of the large diameter of guiding catheters. We studied the feasibility of this approach by sizing the RA by intravascular ultrasound (IVUS) and using 7 Fr (2.31 mm) guiding catheters. Seventeen transradial percutaneous transluminal coronary rotational atherectomy (PTCRA) procedures were performed in 16 patients, mean age 62 +/- 12 years, for a total of 19 vessels treated. The mean RA diameter was 2.9 +/- 0.36 mm and the mean reference diameter of the treated coronary vessels was 2.7 +/- 0.45 mm. The mean coronary percent stenosis was 74% +/- 10%, the mean minimum lumen diameter was 0.76 +/- 0.35 mm, and the mean lesion length was 16 +/- 19 mm. Ten vessels were treated with rotational atherectomy alone, or with adjunctive high pressure balloon angioplasty, achieving an acute lumen gain of 0.8 +/- 0.4 mm (P = 0.001). Nine arteries had stent implantation in addition to rotational atherectomy, resulting in an acute lumen gain of 2.4 +/- 0.5 mm (P = 0.001). The success rate was 94%. There were no vascular complications. Two patients had a non-Q myocardial infarction. In conclusion, transradial PTCRA when used in conjunction with IVUS of the RA is a safe and feasible procedure in selected cases. This may be an alternative approach of revascularization technique especially for patients with limited vascular access and for those who require early ambulation or early discharge from the hospital. Cathet. Cardiovasc. Intervent. 51: 234-238, 2000. (C) 2000 Wiley-Liss, Inc
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