1,720,975 research outputs found
AIM, un motivo invariante di 8 paia di basi presente nei geni nucleari per l’ATP synthase di Drosophila melanogaster e Anopheles gambiae
No full textMutation generating a fragment of the major heat-shock inducible polipeptide in Drosophila melanogaster
No full textGenetic determinants of Glutamine Synthetase in Drosophila melanogaster: role of the 10B8-11 region
No full textInduction by hydrocortisone 21-sodium succinate of the 70K heat-shock polypeptide in isolated salivary glands of Drosophila melanogaster.
No full textThe vertebrate steroid hormone hydrocortisone-21-sodium succinate induces in isolated salivary glands of
Drosophila melanogaster 3rd instar larvae a protein identified as the 70K heat-shock polypeptide by 1- and 2-dimensional
gel electrophoresis analysis. This response is accompanied by significant induction of the puffs 87A and 87C
Exalign: a new method for comparative analysis of exon-intron gene structures
Full text linkThe evolution of genes is usually studied and reconstructed at the sequence level, that is, by comparing and aligning their genomic, transcript or protein sequences. However, including the exonintron structure of genes in the analysis can provide further and useful information, for example to draw reliable phylogenetic relationships left unsolved by traditional sequence-based evolutionary studies, or to shed further light on patterns of intron gain and loss. In spite of this, no tool especially devised for this task is currently available. In this work we present Exalign, an algorithm designed to retrieve, compare and search for the exon-intron structure of existing gene annotations, that has been implemented in a software tool freely accessible through a web interface as well as available for download. We present different applications of our method, from the reconstruction of the evolutionary history of homologous gene families to the detection of as of today unknown cases of intron loss in human and rodents, and, remarkably, two never reported intron gain events in human and mouse. The web interface for accessing Exalign is available at http:// www.pesolelab.it/exalign/ or http:// www.beacon.unimi.it/exalign/
Genetic determinants of Glutamine Synthetase in Drosophila melanogaster: A gene for Glutamine Synthetase I resides in the 21B5-6 region
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Riarrangiamenti genomici mediati dalla trasposizione di FB: il caso di ospA5 in Drosophila melanogaster
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