863 research outputs found
Dedans et dehors. L’uso della sezione nei libri e nei fumetti di Annette Tison e Talus Taylor
No full textTra le diverse forme della rappresentazione le proiezioni
con il metodo di Monge sono quelle che
maggiormente si distaccano dall’esperienza visiva
e richiedono competenze di lettura grafica e capacità
di astrazione. Tra le applicazioni al disegno
di architettura, poi, la sezione è certamente quella
che, in primis, mette in questione la distanza
tra immagine e ‘forma’ e assume a oggetto della
mimesi rappresentativa l’intima struttura degli
edifici piuttosto che la loro apparenza visibile.
Ciononostante, nell’illustrazione per l’infanzia la
sezione verticale (in minore misura la pianta) ha
una tradizione solida e corposa.
Il presente lavoro prende in esame l’uso della sezione
nell’opera di Annette Tison (architetto) e Talus
Taylor (matematico e naturalista), noti principalmente
per aver dato vita al celebre personaggio Barbapapa
ma autori in realtà di numerosi libri illustrati
e fumetti per l’infanzia, dedicati a temi diversificati
e in gran parte rivolti a un pubblico molto giovane,
compreso quello in età prescolare. A partire dall’analisi
di un campione di oltre novanta volumi (tra libri,
riviste e albi a fumetti) pubblicati in Italia, Francia e
Stati Uniti tra i primi anni Settanta e la metà degli
anni Ottanta, il saggio analizza i diversi usi che gli
autori fanno della sezione. Tali applicazioni spaziano
da quella più tradizionale che consente ai giovani
lettori di ‘entrare’ nelle case per scoprire la vita dei
personaggi tra le mura domestiche, ad altre più insolite
e mirate a trasmettere un contenuto genuinamente
tecnico, raro nelle proposte per questa fascia
d’età. Esplorando queste illustrazioni è infatti possibile
trovare elementi strutturali, macchine, dettagli
architettonici, caratteri costruttivi dell’edilizia storica
analizzati con precisione, fino ad arrivare a testi specificamente
dedicati alla progettazione architettonica
tout court e all’uso del disegno ai fini progettuali. Nonostante la spontaneità, l’immediatezza e l’apparente
elementarità dei disegni, dalle illustrazioni
emerge, a uno sguardo più attento, un contenuto
tecnico-disciplinare composito, attinente all’architettura,
all’ingegneria, alla meccanica con incursioni
nelle scienze naturali e nelle stesse discipline
del disegno tecnico che appare non solo come applicazione
ma anche come tema stesso della narrazione.
Della trasmissione di questi contenuti la sezione
si fa veicolo privilegiato e specifico, con una
naturalezza e una capacità di entrare in sintonia
con i contesti narrativi e gli immaginari dell’infanzia
che pochi altri autori hanno dimostrato con
pari pertinenza e ampiezza di produzione.Among the different representation forms,
projections using Monge’s method are the most
detached from the visual experience and require
graphic reading and abstraction skills. Among
the orthographic projection method applications
to architectural drawing, the section is certainly
the one that, first of all, requests the distance
between image and ‘form’ and assumes as the
object of representative mimesis the intimate
structure of buildings rather than their visible
appearance. Nevertheless, in illustration for
children, the vertical section (to a lesser extent
the plan) has a solid, full-bodied tradition.
This essay examines the use of the section in the
work of Annette Tison (architect) and Talus Taylor
(mathematician and naturalist), mainly known
as creators of the famous character Barbapapa,
but also authors of numerous illustrated books
and comics for children, dedicated to a variety
of themes and largely aimed at a very young
audience, including preschoolers.
Starting from the analysis of a sample of over ninety
volumes (including books, journals and comic
books) published in Italy, France, and the United
States between the early 1970s and mid-1980s, the
paper analyses the different uses the authors make
of the section. These uses range from the more
traditional one that allows young readers to ‘enter’
homes to discover the characters’ lives in their
home to more unusual ones. Some drawings indeed
transmit a genuinely technical content, rare in the
proposals for this age group. In these illustrations,
we find structural elements, machines, architectural
details, and precise portraits of historical buildings’
construction features. Furthermore, some works
specifically concern the theme of architecture
design tout court and drawing for design purposes. Despite the spontaneity, naturalness, and
apparent simplicity of the drawings, the
illustrations reveal, at a closer look, a composite
technical-disciplinary content relating to
architecture, engineering, mechanics, with forays
into the natural sciences and the disciplines
of technical drawing itself, which appears not
only as an application but also as a theme of the
narrative. The sections become privileged and
specific medium for these contents in Tison and
Taylor’s illustrations. In their works, drawings
certainly witness a high and rare degree of
harmony with the childhood narrative and
imagery, as a few times before
De l'Age du Fer au 1er siècle après J.-C. : vestiges d'habitats à Hastingues (Landes) (Fouille de sauvetage sur le tracé de l'autoroute A 64)
No full textOn the outline of the highway A 64, an emergency excavation has been done in the Hastingues site in 1988. The excavation which has concerned an area of 3 ha has shown précarious habitats with secondary structures (fire places, pits, ditch). This remains concerned 3 periods (1er Iron Age, II-I century before J.-C. , begining of the I century after J.-C.). This excavation shows a certain interest as it is original in this region, very poor of this known type of habitats ; it is also noteworthy through the abondance of ceramics which have been discovered in this context.Sur le tracé de l’autoroute A 64, le site d’Hastingues a fait l’objet d’une fouille de sauvetage en 1988. La fouille, portant sur une surface de près de 3 hectares, a mis au jour des habitats précaires dotés de structures annexes (foyers, fosses dépotoirs, fossé). Ces vestiges appartiennent à différentes périodes (Premier Age du Fer, IIe siècle-Ier siècle avant J.-C., début du 1er siècle après J.-C.). Le site fouillé présente un intérêt certain du fait de son originalité dans la région, très pauvre en habitats connus de ce type ; il est aussi remarquable par l’abondance du mobilier céramique découvert dans ce contexte.Riuné-Lacabe Sylvie, Tison Suzanne. De l'Age du Fer au 1er siècle après J.-C. : vestiges d'habitats à Hastingues (Landes) (Fouille de sauvetage sur le tracé de l'autoroute A 64). In: Aquitania : une revue inter-régionale d'archéologie, tome 8, 1990. pp. 187-228
Heparin induces apoptosis in lymphocytes from B-cell chronic lymphocytic leukemia
No full textIt has been shown that glycosaminoglycans play a role in the regulation of immune response. In particular, heparin exerts an antiproliferative and apoptotic action in different cellular systems. In this study we evaluate whether heparin can also induce a naturally occurring programmed cell death in lymphocytes from B-chronic lymphocytic leukemia (B-CLL), a neoplastic lineage where apoptosis is blocked by the expression of the proto-oncogene bcl-2. Peripheral blood lymphocytes (PBL) from 7 cases of B-CLL patients in different stages were cultured with three different heparin sodium concentrations for 4 days. Apoptosis was evaluated by agarose gel electrophoresis and by cytofluorimetric analysis. Bcl-2 expression was tested by flow cytometric analysis and immunohistochemistry on cytospin preparations. Agarose gel electrophoresis showed the characteristic DNA fragmentation pattern of apoptosis in all the cases of B-CLL stage III and IV after heparin incubation. DNA from normal and neoplastic lymphocytes cultured without heparin did not undergo spontaneous apoptosis. Cytofluorimetric analysis confirmed the agarose gel pattern and found a level of apoptosis over 50% after culture of neoplastic PBL with heparin. In these cases bcl-2 expression was found to be significantly reduced after heparin incubation when comparing to bcl-2 level before incubation. Our data adds further evidence regarding the potential role of heparin in oncogene inhibition and in apoptosis induction. In particular, the induction of apoptosis in neoplastic lymphocytes by heparin may have a role in the complicated field of interactions between the immune system and the blood vessels by glycosaminoglycans
Ice shelf / ocean interactions at the front of Hells Gate Ice Shelf (Terra Nova Bay, Antarctica)
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