112 research outputs found

    Oral History Interview: Patricia Garza (Mechi)

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    This interview is one of series conducted concerning the Oral History of Appalachia. Mechi was an author, teacher, social worker, and healer. Her ancestry was Choctaw, Cherokee, and Irish. She discusses: living in Mexico before she moved to Appalachia; comparisons between Native American spirituality and Buddhism; her experiences with different religions; Native American culture; relationships between men and women and her views on the differences between men and women, with some discussion on abusive relationships; her social work; the government welfare program; her negative views about modern America; and her views on multicultural America.https://mds.marshall.edu/oral_history/1434/thumbnail.jp

    Microsatellite instability as biomarker for risk of multiple primary malignancies of the upper aerodigestive tract

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    Head and neck cancer (HNC) patients are at high risk of developing second primary tumors of the upper aerodigestive tract and this is a chief cause of death. Genomic instability reflecting the propensity and the susceptibility of the genome to acquire multiple alterations is considered a driving force behind multiple carcinogenesis and the alterations of the length of single repetitive genomic sequences or microsatellite instability (MI), implicating impaired DNA repair mechanisms, and could be a sensitive marker for assessing genomic instability in multiple HNC. To investigate whether a genetic defect(s) involving the mismatch repair system constitutes a risk factor in patients with multiple head and neck cancer, we examined replication errors (RER) at 10 microsatellite loci in 21 primary and 5 second primary cancers in 21 patients with multiple malignancies of the upper aerodigestive tract, in comparison with match-paired primary HNC from patients without multiple malignancies. A RER+phenotype (alterations at â¥2 loci) was observed at 10 microsatellite alterations on chromosomes 2, 3, 11, 17 in at least one tumor from 15 out of 21 (71.5%) patients with multiple primary cancers but only in 11 tumors from 40 (27.5%) HNC patients with single cancer (P=0.001). A RER+phenotype was also associated with a positive familial cancer history (P=0.046). Our results suggest that a genetic instability may play an important role in the pathogenesis of multiple primary cancers and that testing for MI in a primary HNC may be useful in detecting patients with high risk for developing multiple malignancies of the upper aerodigestive tract

    Immunities and privileges of the staff of representatives of states to the international organizations

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    In connection with the appearance in international law of various forms of external relations between subjects, the need to distinguish immunities of employees of those or other organizations involved in the activities of these entities is rising. This article provides a deep analysis of the legal framework providing to employees immunities from the international representatives (eg, the Vienna Convention of 1975, the Convention on the Privileges and Immunities of the United Nations, the UN Agreement - US headquarters, etc.). The author raise the question of accreditation of employees, by whom is represented organization. Also, the article considers decisions of the courts of different countries (USA, Italy, etc.) on issues of the prosecution for crimes of the persons having special status, and their families. Author demonstrates the examples for depending of the results for the recognition of the immunity from jurisdiction of the representatives or the persons entitled to them on the national legislation

    EFFECT OF PROJECT MANAGEMENT TRIPLE CONSTRAINTS ON MAIZE PRODUCTION: A CASE OF ONE ACRE FUND KAKAMEGA COUNTY

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    Abstract: The Triple Constraint is a model that incorporates cost, time and scope as determinants of the quality of the output realized. All over the world, project managers have appreciated the role of the Iron Triangle as a model for analyzing and their projects. Project management triple constraint has proved to be a handy tool. One Acre Fund is an organization that is based in Kenya, Rwanda, Tanzania, Zambia, Malawi and Uganda with the aim of loaning farmers farm inputs and training them on the right crops to plant at given seasons, proper agronomic practices, altitudes and soil health. Among the crops planted include: maize, beans, sorghum, rice, soy beans onions, kales, other horticultural crops and trees seedlings among others. For One Acre Fund farmers to manage its projects well, they should consider applying Iron/project Triangle in order to ensure high maize adoption over other crops and high maize crop production is not only successful to the organization but the harvests also meet the needs of the farmers as well. The study aimed at examining the effects of the project management triple constraints on maize production among One Acre Fund farmers in Kakamega County. Specifically, the study was to: investigate the effect of project quality; assess the effect of project cost; determine the effect of project time; and evaluate the effect of project scope on maize production among One Acre Fund farmers in Kakamega County. the study was underpinned by the: Models of Project Management Triple Constraints; Theory of PM Triangle quality and the Theory of Equitable Relationship. Descriptive survey design was adopted and the targeted population was One Acre Fund farmers in Kakamega county totaling to 50,670. A sample of 100 farmers was used. The study also found that 32.4% of variation in maize production among OAF farmers in Kakamega County was explained by project quality and also11.7% of variation of maize production among One Acre Fund farmers in Kakamega County was explained by project cost. Keywords: project management triple constraints, maize production, one-acre fund. Title: EFFECT OF PROJECT MANAGEMENT TRIPLE CONSTRAINTS ON MAIZE PRODUCTION: A CASE OF ONE ACRE FUND KAKAMEGA COUNTY Author: Caleb Mechi Wakoli, Dr. Muchelule Yusuf International Journal of Management and Commerce Innovations ISSN 2348-7585 (Online) Vol. 10, Issue 1, April 2022 - September 2022 Page No: 414-423 Research Publish Journals Website: www.researchpublish.com Published Date: 22-August-2022 DOI: https://doi.org/10.5281/zenodo.7015086 Paper Download Link (Source) https://www.researchpublish.com/papers/effect-of-project-management-triple-constraints-on-maize-production-a-case-of-one-acre-fund-kakamega-countyInternational Journal of Management and Commerce Innovations, ISSN 2348-7585 (Online), Research Publish Journals, Website: www.researchpublish.co

    Il Memorandum Malvestiti. Appunti sul riarmo e sulla politica economica italiana all'inizio degli anni Cinquanta

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    Analisi del Memorandum sul riarmo italiano elaborato da Piero Malvestiti e della sua filosofia ispiratrice. Il testo è analizzato attraverso fonti primarie inedite, e inquadrato nell'ambito delle politiche statunitensi, del piano Marshall e delle politiche di produttività

    Bibliography

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    Abdelal, Ravi. “Razlichnoe ponimanie vzaimozavisimosti: natsionalnaia bezopasnost’ i torgovlia energoresursami.” In Mechi i orala (Russian translation of Swords and Sustenance), ed. R. Legvold and C. Wallander, 125–56. Cambridge: MIT Press, 2003. Abdziralovich, Ignat. Advechnym shliakham, Dasledziny Belaruskaga Svetagliadu. Minsk: Navuka i tekhnika, 1993,http://knihi.com/abdziralovic/slach.html. Adkrytaie gramadstva. “Demokratiia i natsionalism kak alfa i omega politiches ko go protsessa.” No..

    Иммунитеты и привилегии персонала представительств государств при международных организациях

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    In connection with the appearance in international law of various forms of external relations between subjects, the need to distinguish immunities of employees of those or other organizations involved in the activities of these entities is rising. This article provides a deep analysis of the legal framework providing to employees immunities from the international representatives (eg, the Vienna Convention of 1975, the Convention on the Privileges and Immunities of the United Nations, the UN Agreement - US headquarters, etc.). The author raise the question of accreditation of employees, by whom is represented organization. Also, the article considers decisions of the courts of different countries (USA, Italy, etc.) on issues of the prosecution for crimes of the persons having special status, and their families. Author demonstrates the examples for depending of the results for the recognition of the immunity from jurisdiction of the representatives or the persons entitled to them on the national legislation.В связи с возникновением в международном праве различных форм внешних сношений между субъектами необходимо проведение разграничений иммунитетов служащих тех или иных организаций, участвующих в деятельности этих субъектов. В статье проводится глубокий анализ нормативно-правовой базы, предоставляющей работникам международных представительств иммунитеты (например, Венская конвенция 1975 г., Конвенция о привилегиях и иммунитетах Объединенных Наций, Соглашения ООН - США о штаб-квартире и др.). Автором поднимается вопрос об аккредитации служащих при представляемой организации. Также в статье рассматриваются решения судов различных государств (США, Италии и др.) по вопросам привлечения к ответственности за правонарушения лиц, обладающих специальным статусом, и членов их семей. Автором демонстрируются примеры зависимости от национального законодательства результатов по делам о признании иммунитета от юрисдикции представителей или лиц, имеющих право на них
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