6,834 research outputs found
On a special class of wiretap channels
No full textBibliography: leaf 12.NSF Grants GK-33250 and Eng-10173, AFOSR Contract F44620-73-C-0065, Grant ONR/N0014-75-C-1183 and NSF/ENC-76-24447.by S. K. Leung-Yan-Cheong
Bastid (M.), Bergère (M.-C), Chesneaux (J.) : Histoire de la Chine, t. II : de la guerre franco-chinoise à la fondation du parti communiste chinois, 1885-1921
No full textCheong Weng Eang. Bastid (M.), Bergère (M.-C), Chesneaux (J.) : Histoire de la Chine, t. II : de la guerre franco-chinoise à la fondation du parti communiste chinois, 1885-1921. In: Revue française d'histoire d'outre-mer, tome 61, n°222, 1er trimestre 1974. pp. 186-187
Evidence-based management of tubal disease and infertility
No full textThere is a multitude of tests available for the investigation of tubal disease. This review gives an overview of the use of hysterosalpingography (HSG), the laparoscopy and dye test, hystero-contrast-sonography (HyCoSy), falloposcopy and fertiloscopy in the evaluation of the fallopian tubes. The current sensible approach would be to offer HSG for women with a low risk of tubal disease as HSG is a valid and accurate test used to diagnose tubal patency in subfertile couples. In women with suspected underlying gynaecological pathology such as endometriosis or pelvic inflammatory disease, and/or in the presence of tubal blockage on HSG, one should proceed with the laparoscopy and dye test to confirm or refute the diagnosis. The National Institute for Clinical Excellence also recommends the use of HyCoSy where the service is available as this is as effective as HSG in diagnosing tubal disease in low-risk women.</p
Analyst forecasts and stock price informativeness: some international evidence on the role of audit quality
No full textAbstract not availableChee Seng Cheong, Ralf Zurbrueg
On some aspects of random walks for modelling mobility in a communication network
No full textBibliography: leaf 16.Grant ONR/N00014-75-C-1183.S. K. Leung-Yan-Cheong, E. R. Barnes
The size effect: Australian evidence
No full textChee Seng Cheong A Fin and Justin Steinerthttp://www.finsia.com/Content/NavigationMenu/Informationservices/JASSA/default.ht
Prognostic value of changes in serum carcinoembryonic antigen levels for preoperative chemoradiotherapy response in locally advanced rectal cancer
No full textBACKGROUND: Preoperative chemoradiotherapy (CRT) is a standard treatment modality for locally advanced rectal cancer. However, CRT alone cannot improve overall survival. Approximately 20% of patients with CRT-resistant tumors show disease progression. Therefore, predictive factors for treatment response are needed to identify patients who will benefit from CRT. We theorized that the prognosis may vary if patients are classified according to pre- to post-CRT changes in carcinoembryonic antigen (CEA) levels.
AIM: To identify patients with locally advanced rectal cancer for preoperative chemoradiotherapy based on carcinoembryonic antigen levels.
METHODS: We retrospectively included locally advanced rectal cancer patients who underwent preoperative CRT and curative resection between 2011 and 2017. Patients were assigned to groups A, B, and C based on pre- and post-CRT serum CEA levels: Both > 5; pre > 5 and post RESULTS: The cohort comprised 145 patients; of them, 27, 43, and 65 belonged to groups A, B, and C, respectively, according to changes in serum CEA levels before and after CRT. Pre- (P < 0.001) and post-CRT (P < 0.001) CEA levels and the ratio of down-staging (P = 0.013) were higher in Groups B and C than in Group A. The ratio of pathologic tumor regression grade 0/1 significantly differed among the groups (P = 0.003). Group C had the highest number of patients showing pCR (P < 0.001). Most patients with pCR showed pre- and post-CRT CEA levels < 5 ng/mL (P < 0.001, P = 0.008). Pre- and post-CRT CEA levels were important risk factors for pCR (OR = 18.71; 95%CI: 4.62-129.51, P < 0.001) and good response (OR = 5.07; 95%CI: 1.92-14.83, P = 0.002), respectively. Pre-CRT neutrophil-lymphocyte ratio and post-CRT T >/= 3 stage were also prognostic factors for pCR or good response.
CONCLUSION: Pre- and post-CRT CEA levels, as well as change in CEA levels, were prognostic markers for treatment response to CRT and may facilitate treatment individualization for rectal cancer
A single-nucleotide natural variation (U4 to C4) in an influenza A virus promoter exhibits a large structural change: implications for differential viral RNA synthesis by RNA-dependent RNA polymerase
No full textThe influenza A virus promoter is recognized by the influenza A virus RNA-dependent RNA polymerase, and directs both transcription and replication of the viral RNA genome. Within the sequence of this promoter, flu strains exhibit a natural, unique variation, either a U or a C, at the fourth position from the 3' end. Promoters that contain a C residue (C4 promoter), which are invariably found in genome segments that encode the three RNA polymerase subunits (PB1, PB2 and PA), down-regulate transcription but activate genome replication. Here, we have determined the structure of the C4 promoter by NMR spectroscopy and compared it with the structure of the U4 promoter, which was determined previously. The structure of the internal loop in the C4 promoter is similar to that of the U4 promoter. However, the terminal stem of the C4 promoter is strikingly different from that of the U4 promoter. These structural data suggest that the internal loop is important for polymerase binding to the promoter, and the terminal stem is crucial for differential regulation of transcription and replication
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